5ADSB

Crystal structure of human tankyrase 2 in complex with od39
Total Genus 1
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords TANKYRASE-2
publication title Development and Structural Analysis of Adenosine Site Binding Tankyrase Inhibitors.
pubmed doi rcsb
source organism Homo sapiens
total genus 1
structure length 46
sequence length 46
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5adsB00
4L0BC 4KZUC 4L2KC 5ADSB 4UVPB 4HKNC 4HKIC 4UI8C 5FPFC 4L2GC 4HLGC 4HLFC 4L0IC 4KZLC 5ADRB 4HMHC 5C5RC 4UI7C 5ADTB 4HL5C 4HLKC 4L34C 4HLMC 4L10C 4L32C 4HKKB 4L0VC 4UI6C 4L0TC 5C5PC 4L2FC 5ADQB 4KZQC 4L09C 4UI3C 4L33C 4L0SC 4UI4C 5C5QC 4HLHC 4L31C 4UI5C
chains in the Genus database with same CATH superfamily
4L0BC 4KZUC 3D55A 4L2KC 5ADSB 4UVPB 4HKNC 4HKIC 4UI8C 5FPFC 4L2GC 2A6QA 4HLGC 4HLFC 4L0IC 4KZLC 5ADRB 3OEIA 3OEIE 4HMHC 4ZLXA 3G5OA 5C5RC 4UI7C 3HS2A 3HJ6A 5ADTB 4HL5C 4HLKC 4L34C 4HLMC 4L10C 4L32C 3CTOA 2ZIXB 4HKKB 4L0VC 2ODKA 3K6QA 3KH2E 4UI6C 4L0TC 5C5PC 4L2FC 4ZM2A 5ADQB 4KZQC 4L09C 4UI3C 4ZM0A 4L33C 3K33B 4L0SC 4UI4C 5C5QC 3HRYA 4HLHC 4L31C 4UI5C
chains in the Genus database with same CATH topology
4L0BC 4KZUC 4L2KC 5ADSB 4UVPB 4HKNC 4HKIC 4UI8C 5FPFC 4L2GC 4HLGC 4HLFC 4L0IC 4KZLC 5ADRB 4HMHC 5C5RC 4UI7C 3HJ6A 5ADTB 4HL5C 4HLKC 4L34C 4HLMC 4L10C 4L32C 2ZIXB 4HKKB 4L0VC 4UI6C 4L0TC 5C5PC 4L2FC 5ADQB 4KZQC 4L09C 4UI3C 4L33C 4L0SC 4UI4C 5C5QC 4HLHC 4L31C 4UI5C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L0B C;  4KZU C;  4L2K C;  5ADS B;  4UVP B;  4HKN C;  4HKI C;  4UI8 C;  5FPF C;  4L2G C;  4HLG C;  4HLF C;  4L0I C;  4KZL C;  5ADR B;  4HMH C;  5C5R C;  4UI7 C;  5ADT B;  4HL5 C;  4HLK C;  4L34 C;  4HLM C;  4L10 C;  4L32 C;  4HKK B;  4L0V C;  4UI6 C;  4L0T C;  5C5P C;  4L2F C;  5ADQ B;  4KZQ C;  4L09 C;  4UI3 C;  4L33 C;  4L0S C;  4UI4 C;  5C5Q C;  4HLH C;  4L31 C;  4UI5 C; 
#chains in the Genus database with same CATH topology
 4L0B C;  4KZU C;  3D55 A;  4L2K C;  5ADS B;  4UVP B;  4HKN C;  4HKI C;  4UI8 C;  5FPF C;  4L2G C;  2A6Q A;  4HLG C;  4HLF C;  4L0I C;  4KZL C;  5ADR B;  3OEI A;  3OEI E;  4HMH C;  4ZLX A;  3G5O A;  5C5R C;  4UI7 C;  3HS2 A;  3HJ6 A;  5ADT B;  4HL5 C;  4HLK C;  4L34 C;  4HLM C;  4L10 C;  4L32 C;  3CTO A;  2ZIX B;  4HKK B;  4L0V C;  2ODK A;  3K6Q A;  3KH2 E;  4UI6 C;  4L0T C;  5C5P C;  4L2F C;  4ZM2 A;  5ADQ B;  4KZQ C;  4L09 C;  4UI3 C;  4ZM0 A;  4L33 C;  3K33 B;  4L0S C;  4UI4 C;  5C5Q C;  3HRY A;  4HLH C;  4L31 C;  4UI5 C; 
#chains in the Genus database with same CATH homology
 4L0B C;  4KZU C;  4L2K C;  5ADS B;  4UVP B;  4HKN C;  4HKI C;  4UI8 C;  5FPF C;  4L2G C;  4HLG C;  4HLF C;  4L0I C;  4KZL C;  5ADR B;  4HMH C;  5C5R C;  4UI7 C;  3HJ6 A;  5ADT B;  4HL5 C;  4HLK C;  4L34 C;  4HLM C;  4L10 C;  4L32 C;  2ZIX B;  4HKK B;  4L0V C;  4UI6 C;  4L0T C;  5C5P C;  4L2F C;  5ADQ B;  4KZQ C;  4L09 C;  4UI3 C;  4L33 C;  4L0S C;  4UI4 C;  5C5Q C;  4HLH C;  4L31 C;  4UI5 C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...