1DSZB

Structure of the rxr/rar dna-binding domain heterodimer in complex with the retinoic acid response element dr1
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
84
structure length
84
Chain Sequence
GSFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3')
total genus 17
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2000-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 1dszB00
5EMPA 3G9PA 3VEKC 4OORA 5E6DA 4AA6A 4HCAA 5CC0A 3G9JA 2ENVA 2NLLA 2GDAA 1GATA 5E6CA 2VUSI 1DSZB 3G8XA 4OLNA 4HC9A 3DZYD 1LV3A 5E69A 1KB6A 1LO1A 2VUUI 2NLLB 3G97A 3G6TA 5CBXA 1BY4A 1GA5A 5EMCA 4CN3A 5KRBB 1CITA 4GATA 1DSZA 5EMQA 3G8UA 1GLUA 3G9MA 3VD6C 5CBYA 2KAEA 1GNFA 2HANB 1R4OA 5CC1A 4TNTA 2M9WA 3FYLA 3G9IA 4CN7A 3DFVC 1HRAA 3G6RA 1R0NB 1GAUA 2GATA 2HANA 6GATA 1RGDA 3G6UA 3E00A 1RXRA 5GATA 3GATA 5E6BA 3DFXA 1GDCA 1HCQA 1KB4A 4CN5A 4TMAI 4HC7A 4HN6A 1R0NA 3G99A 2C7AA 1R4IA 4OV7A 3DZUA 1KB2A 2FF0A 4ONDA 4NQAB 4CN3D 7GATA 5E6AA 4IQRA 4HN5A 3DZYA 3M9EA 1R0OB 1YNWB 5CBZA 1LATA 3DZUD 2EBLA 1HCPA 3G6PA 1R4RA 4CN2C 2A66A 1HLZA 2VUTI 1R0OA 3G9OA 3CBBA 5L0MA 3G6QA 3E00D 1A6YA 1YNWA
chains in the Genus database with same CATH superfamily
5EMPA 3G9PA 3VEKC 4OORA 5E6DA 4AA6A 4HCAA 5CC0A 3G9JA 3G27A 2ENVA 2NLLA 2GDAA 1GATA 5E6CA 2VUSI 1DSZB 3G8XA 4OLNA 4HC9A 3DZYD 1LV3A 5E69A 1KB6A 1LO1A 2VUUI 2NLLB 3G97A 3G6TA 5CBXA 1BY4A 1GA5A 5EMCA 4CN3A 5KRBB 1CITA 4GATA 1DSZA 5EMQA 3G8UA 1GLUA 3G9MA 3VD6C 5CBYA 2DS5A 2KAEA 1GNFA 2HANB 1R4OA 5CC1A 4TNTA 2M9WA 3FYLA 3G9IA 4CN7A 3DFVC 1HRAA 3G6RA 1R0NB 1GAUA 2GATA 2HANA 6GATA 1RGDA 3G6UA 3E00A 1RXRA 5GATA 3GATA 2DS6A 5E6BA 3DFXA 1GDCA 1HCQA 1KB4A 4CN5A 4TMAI 4HC7A 4HN6A 1R0NA 3G99A 2C7AA 1R4IA 4OV7A 3DZUA 1KB2A 2FF0A 4ONDA 4NQAB 4CN3D 7GATA 5E6AA 4IQRA 4HN5A 3DZYA 3M9EA 1R0OB 1YNWB 5CBZA 1LATA 3DZUD 2EBLA 1HCPA 3G6PA 1R4RA 4CN2C 2A66A 1HLZA 2VUTI 1R0OA 3G9OA 3CBBA 5L0MA 2DS8A 3G6QA 3E00D 1A6YA 1YNWA
chains in the Genus database with same CATH topology
5EMPA 3G9PA 3VEKC 4OORA 5E6DA 4AA6A 4HCAA 5CC0A 3G9JA 2ENVA 2NLLA 2GDAA 1GATA 5E6CA 2VUSI 1DSZB 3G8XA 4OLNA 4HC9A 3DZYD 1LV3A 5E69A 1KB6A 1LO1A 2VUUI 2NLLB 3G97A 3G6TA 5CBXA 1BY4A 1GA5A 5EMCA 4CN3A 5KRBB 1CITA 4GATA 1DSZA 5EMQA 3G8UA 1GLUA 3G9MA 3VD6C 5CBYA 2KAEA 1GNFA 2HANB 1R4OA 5CC1A 4TNTA 2M9WA 3FYLA 3G9IA 4CN7A 3DFVC 1HRAA 3G6RA 1R0NB 1GAUA 2GATA 2HANA 6GATA 1RGDA 3G6UA 3E00A 1RXRA 5GATA 3GATA 5E6BA 3DFXA 1GDCA 1HCQA 1KB4A 4CN5A 4TMAI 4HC7A 4HN6A 1R0NA 3G99A 2C7AA 1R4IA 4OV7A 3DZUA 1KB2A 2FF0A 4ONDA 4NQAB 4CN3D 7GATA 5E6AA 4IQRA 4HN5A 3DZYA 3M9EA 1R0OB 1YNWB 5CBZA 1LATA 3DZUD 2EBLA 1HCPA 3G6PA 1R4RA 4CN2C 2A66A 1HLZA 2VUTI 1R0OA 3G9OA 3CBBA 5L0MA 3G6QA 3E00D 1A6YA 1YNWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EMP A;  3G9P A;  3VEK C;  4OOR A;  5E6D A;  4AA6 A;  4HCA A;  5CC0 A;  3G9J A;  2ENV A;  2NLL A;  2GDA A;  1GAT A;  5E6C A;  2VUS I;  1DSZ B;  3G8X A;  4OLN A;  4HC9 A;  3DZY D;  1LV3 A;  5E69 A;  1KB6 A;  1LO1 A;  2VUU I;  2NLL B;  3G97 A;  3G6T A;  5CBX A;  1BY4 A;  1GA5 A;  5EMC A;  4CN3 A;  5KRB B;  1CIT A;  4GAT A;  1DSZ A;  5EMQ A;  3G8U A;  1GLU A;  3G9M A;  3VD6 C;  5CBY A;  2KAE A;  1GNF A;  2HAN B;  1R4O A;  5CC1 A;  4TNT A;  2M9W A;  3FYL A;  3G9I A;  4CN7 A;  3DFV C;  1HRA A;  3G6R A;  1R0N B;  1GAU A;  2GAT A;  2HAN A;  6GAT A;  1RGD A;  3G6U A;  3E00 A;  1RXR A;  5GAT A;  3GAT A;  5E6B A;  3DFX A;  1GDC A;  1HCQ A;  1KB4 A;  4CN5 A;  4TMA I;  4HC7 A;  4HN6 A;  1R0N A;  3G99 A;  2C7A A;  1R4I A;  4OV7 A;  3DZU A;  1KB2 A;  2FF0 A;  4OND A;  4NQA B;  4CN3 D;  7GAT A;  5E6A A;  4IQR A;  4HN5 A;  3DZY A;  3M9E A;  1R0O B;  1YNW B;  5CBZ A;  1LAT A;  3DZU D;  2EBL A;  1HCP A;  3G6P A;  1R4R A;  4CN2 C;  2A66 A;  1HLZ A;  2VUT I;  1R0O A;  3G9O A;  3CBB A;  5L0M A;  3G6Q A;  3E00 D;  1A6Y A;  1YNW A; 
#chains in the Genus database with same CATH topology
 5EMP A;  3G9P A;  3VEK C;  4OOR A;  5E6D A;  4AA6 A;  4HCA A;  5CC0 A;  3G9J A;  3G27 A;  2ENV A;  2NLL A;  2GDA A;  1GAT A;  5E6C A;  2VUS I;  1DSZ B;  3G8X A;  4OLN A;  4HC9 A;  3DZY D;  1LV3 A;  5E69 A;  1KB6 A;  1LO1 A;  2VUU I;  2NLL B;  3G97 A;  3G6T A;  5CBX A;  1BY4 A;  1GA5 A;  5EMC A;  4CN3 A;  5KRB B;  1CIT A;  4GAT A;  1DSZ A;  5EMQ A;  3G8U A;  1GLU A;  3G9M A;  3VD6 C;  5CBY A;  2DS5 A;  2KAE A;  1GNF A;  2HAN B;  1R4O A;  5CC1 A;  4TNT A;  2M9W A;  3FYL A;  3G9I A;  4CN7 A;  3DFV C;  1HRA A;  3G6R A;  1R0N B;  1GAU A;  2GAT A;  2HAN A;  6GAT A;  1RGD A;  3G6U A;  3E00 A;  1RXR A;  5GAT A;  3GAT A;  2DS6 A;  5E6B A;  3DFX A;  1GDC A;  1HCQ A;  1KB4 A;  4CN5 A;  4TMA I;  4HC7 A;  4HN6 A;  1R0N A;  3G99 A;  2C7A A;  1R4I A;  4OV7 A;  3DZU A;  1KB2 A;  2FF0 A;  4OND A;  4NQA B;  4CN3 D;  7GAT A;  5E6A A;  4IQR A;  4HN5 A;  3DZY A;  3M9E A;  1R0O B;  1YNW B;  5CBZ A;  1LAT A;  3DZU D;  2EBL A;  1HCP A;  3G6P A;  1R4R A;  4CN2 C;  2A66 A;  1HLZ A;  2VUT I;  1R0O A;  3G9O A;  3CBB A;  5L0M A;  2DS8 A;  3G6Q A;  3E00 D;  1A6Y A;  1YNW A; 
#chains in the Genus database with same CATH homology
 5EMP A;  3G9P A;  3VEK C;  4OOR A;  5E6D A;  4AA6 A;  4HCA A;  5CC0 A;  3G9J A;  2ENV A;  2NLL A;  2GDA A;  1GAT A;  5E6C A;  2VUS I;  1DSZ B;  3G8X A;  4OLN A;  4HC9 A;  3DZY D;  1LV3 A;  5E69 A;  1KB6 A;  1LO1 A;  2VUU I;  2NLL B;  3G97 A;  3G6T A;  5CBX A;  1BY4 A;  1GA5 A;  5EMC A;  4CN3 A;  5KRB B;  1CIT A;  4GAT A;  1DSZ A;  5EMQ A;  3G8U A;  1GLU A;  3G9M A;  3VD6 C;  5CBY A;  2KAE A;  1GNF A;  2HAN B;  1R4O A;  5CC1 A;  4TNT A;  2M9W A;  3FYL A;  3G9I A;  4CN7 A;  3DFV C;  1HRA A;  3G6R A;  1R0N B;  1GAU A;  2GAT A;  2HAN A;  6GAT A;  1RGD A;  3G6U A;  3E00 A;  1RXR A;  5GAT A;  3GAT A;  5E6B A;  3DFX A;  1GDC A;  1HCQ A;  1KB4 A;  4CN5 A;  4TMA I;  4HC7 A;  4HN6 A;  1R0N A;  3G99 A;  2C7A A;  1R4I A;  4OV7 A;  3DZU A;  1KB2 A;  2FF0 A;  4OND A;  4NQA B;  4CN3 D;  7GAT A;  5E6A A;  4IQR A;  4HN5 A;  3DZY A;  3M9E A;  1R0O B;  1YNW B;  5CBZ A;  1LAT A;  3DZU D;  2EBL A;  1HCP A;  3G6P A;  1R4R A;  4CN2 C;  2A66 A;  1HLZ A;  2VUT I;  1R0O A;  3G9O A;  3CBB A;  5L0M A;  3G6Q A;  3E00 D;  1A6Y A;  1YNW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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