1HCPA

Dna recognition by the oestrogen receptor: from solution to the crystal
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
75
structure length
75
Chain Sequence
MKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription regulation
source organism Homo sapiens
publication title DNA recognition by the oestrogen receptor: from solution to the crystal.
pubmed doi rcsb
molecule keywords HUMAN/CHICKEN ESTROGEN RECEPTOR
total genus 8
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 1993-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 1hcpA00
5L0MA 3VEKC 2A66A 5CBXA 2ENVA 2GDAA 4NQAB 4TNTA 6GATA 4HCAA 3G6TA 1R0OA 3DFXA 1GATA 1HRAA 4GATA 3E00D 4HC7A 3G9PA 2NLLA 3G9MA 7GATA 5CBZA 4OORA 3DZUD 5E69A 3DZYA 1DSZB 1GNFA 4AA6A 4CN3A 3CBBA 1GAUA 1HLZA 1KB2A 4HN6A 1KB4A 3G99A 2FF0A 1GDCA 1YNWA 1LO1A 1DSZA 2GATA 5E6BA 1HCPA 3FYLA 1RXRA 1CITA 2VUTI 1R4OA 5EMQA 4HN5A 2HANB 1HCQA 4CN7A 1R0NB 3DZYD 5EMCA 5E6AA 4CN2C 4CN3D 5EMPA 2VUSI 3DFVC 1RGDA 4IQRA 5CC1A 4CN5A 3G6QA 4TMAI 1A6YA 4OV7A 2KAEA 2EBLA 5GATA 3M9EA 2C7AA 3G6UA 2VUUI 3GATA 1R0OB 1BY4A 3G6PA 3G9IA 1GA5A 1GLUA 1LATA 5CBYA 3G8XA 2NLLB 3G97A 1KB6A 1LV3A 3G9JA 2HANA 2M9WA 3G6RA 1R0NA 3VD6C 3G8UA 4HC9A 3E00A 4OLNA 4ONDA 3DZUA 1YNWB 5E6DA 5E6CA 5CC0A 1R4IA 5KRBB 3G9OA 1R4RA
chains in the Genus database with same CATH superfamily
5L0MA 3VEKC 2A66A 5CBXA 2ENVA 2GDAA 2DS6A 4NQAB 2DS5A 4TNTA 6GATA 4HCAA 3G6TA 1R0OA 3DFXA 1GATA 1HRAA 4GATA 3E00D 4HC7A 3G9PA 2NLLA 3G9MA 7GATA 5CBZA 4OORA 3DZUD 5E69A 3DZYA 1DSZB 1GNFA 4AA6A 4CN3A 3CBBA 1GAUA 1HLZA 1KB2A 4HN6A 1KB4A 3G99A 2FF0A 1GDCA 1YNWA 1LO1A 1DSZA 2GATA 5E6BA 1HCPA 3FYLA 1RXRA 1CITA 2VUTI 1R4OA 5EMQA 4HN5A 2HANB 1HCQA 4CN7A 1R0NB 3DZYD 5EMCA 2DS8A 5E6AA 4CN2C 4CN3D 5EMPA 2VUSI 3DFVC 1RGDA 4IQRA 5CC1A 4CN5A 3G6QA 4TMAI 1A6YA 4OV7A 2KAEA 2EBLA 5GATA 3M9EA 2C7AA 3G6UA 2VUUI 3GATA 1R0OB 1BY4A 3G6PA 3G9IA 1GA5A 1GLUA 1LATA 5CBYA 3G8XA 3G27A 2NLLB 3G97A 1KB6A 1LV3A 3G9JA 2HANA 2M9WA 3G6RA 1R0NA 3VD6C 3G8UA 4HC9A 3E00A 4OLNA 4ONDA 3DZUA 1YNWB 5E6DA 5E6CA 5CC0A 1R4IA 5KRBB 3G9OA 1R4RA
chains in the Genus database with same CATH topology
5L0MA 3VEKC 2A66A 5CBXA 2ENVA 2GDAA 4NQAB 4TNTA 6GATA 4HCAA 3G6TA 1R0OA 3DFXA 1GATA 1HRAA 4GATA 3E00D 4HC7A 3G9PA 2NLLA 3G9MA 7GATA 5CBZA 4OORA 3DZUD 5E69A 3DZYA 1DSZB 1GNFA 4AA6A 4CN3A 3CBBA 1GAUA 1HLZA 1KB2A 4HN6A 1KB4A 3G99A 2FF0A 1GDCA 1YNWA 1LO1A 1DSZA 2GATA 5E6BA 1HCPA 3FYLA 1RXRA 1CITA 2VUTI 1R4OA 5EMQA 4HN5A 2HANB 1HCQA 4CN7A 1R0NB 3DZYD 5EMCA 5E6AA 4CN2C 4CN3D 5EMPA 2VUSI 3DFVC 1RGDA 4IQRA 5CC1A 4CN5A 3G6QA 4TMAI 1A6YA 4OV7A 2KAEA 2EBLA 5GATA 3M9EA 2C7AA 3G6UA 2VUUI 3GATA 1R0OB 1BY4A 3G6PA 3G9IA 1GA5A 1GLUA 1LATA 5CBYA 3G8XA 2NLLB 3G97A 1KB6A 1LV3A 3G9JA 2HANA 2M9WA 3G6RA 1R0NA 3VD6C 3G8UA 4HC9A 3E00A 4OLNA 4ONDA 3DZUA 1YNWB 5E6DA 5E6CA 5CC0A 1R4IA 5KRBB 3G9OA 1R4RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L0M A;  3VEK C;  2A66 A;  5CBX A;  2ENV A;  2GDA A;  4NQA B;  4TNT A;  6GAT A;  4HCA A;  3G6T A;  1R0O A;  3DFX A;  1GAT A;  1HRA A;  4GAT A;  3E00 D;  4HC7 A;  3G9P A;  2NLL A;  3G9M A;  7GAT A;  5CBZ A;  4OOR A;  3DZU D;  5E69 A;  3DZY A;  1DSZ B;  1GNF A;  4AA6 A;  4CN3 A;  3CBB A;  1GAU A;  1HLZ A;  1KB2 A;  4HN6 A;  1KB4 A;  3G99 A;  2FF0 A;  1GDC A;  1YNW A;  1LO1 A;  1DSZ A;  2GAT A;  5E6B A;  1HCP A;  3FYL A;  1RXR A;  1CIT A;  2VUT I;  1R4O A;  5EMQ A;  4HN5 A;  2HAN B;  1HCQ A;  4CN7 A;  1R0N B;  3DZY D;  5EMC A;  5E6A A;  4CN2 C;  4CN3 D;  5EMP A;  2VUS I;  3DFV C;  1RGD A;  4IQR A;  5CC1 A;  4CN5 A;  3G6Q A;  4TMA I;  1A6Y A;  4OV7 A;  2KAE A;  2EBL A;  5GAT A;  3M9E A;  2C7A A;  3G6U A;  2VUU I;  3GAT A;  1R0O B;  1BY4 A;  3G6P A;  3G9I A;  1GA5 A;  1GLU A;  1LAT A;  5CBY A;  3G8X A;  2NLL B;  3G97 A;  1KB6 A;  1LV3 A;  3G9J A;  2HAN A;  2M9W A;  3G6R A;  1R0N A;  3VD6 C;  3G8U A;  4HC9 A;  3E00 A;  4OLN A;  4OND A;  3DZU A;  1YNW B;  5E6D A;  5E6C A;  5CC0 A;  1R4I A;  5KRB B;  3G9O A;  1R4R A; 
#chains in the Genus database with same CATH topology
 5L0M A;  3VEK C;  2A66 A;  5CBX A;  2ENV A;  2GDA A;  2DS6 A;  4NQA B;  2DS5 A;  4TNT A;  6GAT A;  4HCA A;  3G6T A;  1R0O A;  3DFX A;  1GAT A;  1HRA A;  4GAT A;  3E00 D;  4HC7 A;  3G9P A;  2NLL A;  3G9M A;  7GAT A;  5CBZ A;  4OOR A;  3DZU D;  5E69 A;  3DZY A;  1DSZ B;  1GNF A;  4AA6 A;  4CN3 A;  3CBB A;  1GAU A;  1HLZ A;  1KB2 A;  4HN6 A;  1KB4 A;  3G99 A;  2FF0 A;  1GDC A;  1YNW A;  1LO1 A;  1DSZ A;  2GAT A;  5E6B A;  1HCP A;  3FYL A;  1RXR A;  1CIT A;  2VUT I;  1R4O A;  5EMQ A;  4HN5 A;  2HAN B;  1HCQ A;  4CN7 A;  1R0N B;  3DZY D;  5EMC A;  2DS8 A;  5E6A A;  4CN2 C;  4CN3 D;  5EMP A;  2VUS I;  3DFV C;  1RGD A;  4IQR A;  5CC1 A;  4CN5 A;  3G6Q A;  4TMA I;  1A6Y A;  4OV7 A;  2KAE A;  2EBL A;  5GAT A;  3M9E A;  2C7A A;  3G6U A;  2VUU I;  3GAT A;  1R0O B;  1BY4 A;  3G6P A;  3G9I A;  1GA5 A;  1GLU A;  1LAT A;  5CBY A;  3G8X A;  3G27 A;  2NLL B;  3G97 A;  1KB6 A;  1LV3 A;  3G9J A;  2HAN A;  2M9W A;  3G6R A;  1R0N A;  3VD6 C;  3G8U A;  4HC9 A;  3E00 A;  4OLN A;  4OND A;  3DZU A;  1YNW B;  5E6D A;  5E6C A;  5CC0 A;  1R4I A;  5KRB B;  3G9O A;  1R4R A; 
#chains in the Genus database with same CATH homology
 5L0M A;  3VEK C;  2A66 A;  5CBX A;  2ENV A;  2GDA A;  4NQA B;  4TNT A;  6GAT A;  4HCA A;  3G6T A;  1R0O A;  3DFX A;  1GAT A;  1HRA A;  4GAT A;  3E00 D;  4HC7 A;  3G9P A;  2NLL A;  3G9M A;  7GAT A;  5CBZ A;  4OOR A;  3DZU D;  5E69 A;  3DZY A;  1DSZ B;  1GNF A;  4AA6 A;  4CN3 A;  3CBB A;  1GAU A;  1HLZ A;  1KB2 A;  4HN6 A;  1KB4 A;  3G99 A;  2FF0 A;  1GDC A;  1YNW A;  1LO1 A;  1DSZ A;  2GAT A;  5E6B A;  1HCP A;  3FYL A;  1RXR A;  1CIT A;  2VUT I;  1R4O A;  5EMQ A;  4HN5 A;  2HAN B;  1HCQ A;  4CN7 A;  1R0N B;  3DZY D;  5EMC A;  5E6A A;  4CN2 C;  4CN3 D;  5EMP A;  2VUS I;  3DFV C;  1RGD A;  4IQR A;  5CC1 A;  4CN5 A;  3G6Q A;  4TMA I;  1A6Y A;  4OV7 A;  2KAE A;  2EBL A;  5GAT A;  3M9E A;  2C7A A;  3G6U A;  2VUU I;  3GAT A;  1R0O B;  1BY4 A;  3G6P A;  3G9I A;  1GA5 A;  1GLU A;  1LAT A;  5CBY A;  3G8X A;  2NLL B;  3G97 A;  1KB6 A;  1LV3 A;  3G9J A;  2HAN A;  2M9W A;  3G6R A;  1R0N A;  3VD6 C;  3G8U A;  4HC9 A;  3E00 A;  4OLN A;  4OND A;  3DZU A;  1YNW B;  5E6D A;  5E6C A;  5CC0 A;  1R4I A;  5KRB B;  3G9O A;  1R4R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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