1HLZA

Crystal structure of the orphan nuclear receptor rev-erb(alpha) dna-binding domain bound to its cognate response element
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
81
structure length
81
Chain Sequence
VLLCKVCGDVASGFHYGVLACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title DNA Deformability as a Recognition Feature in the RevErb Response Element
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*
total genus 13
structure length 81
sequence length 81
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 1hlzA00
3DFXA 5CBYA 1CITA 1R4OA 5CC1A 3G6QA 3CBBA 2A66A 1YNWA 3G9PA 5EMPA 3G9IA 3G9MA 1R4IA 1GLUA 5EMCA 2VUTI 1GA5A 1BY4A 2NLLA 5L0MA 3G6TA 1HCQA 1KB4A 5GATA 5KRBB 1HLZA 5E6AA 1GNFA 5E6CA 4OV7A 3VEKC 2FF0A 4ONDA 4OLNA 3G8UA 2ENVA 1GDCA 2HANA 2VUUI 1RGDA 3FYLA 5E69A 2NLLB 1DSZA 1A6YA 4TNTA 3G97A 1GAUA 1GATA 4CN3D 4IQRA 5CC0A 2EBLA 1R0NA 4CN3A 4OORA 1R0OB 4CN5A 4AA6A 3G99A 5CBZA 3E00D 3E00A 2HANB 1YNWB 1KB2A 1DSZB 4HN6A 1LV3A 4TMAI 5E6BA 1R4RA 1R0NB 2C7AA 1LATA 5CBXA 1HRAA 2M9WA 3DFVC 1HCPA 1LO1A 2GATA 3G6UA 4HC7A 7GATA 1KB6A 1RXRA 6GATA 3G8XA 4HCAA 2GDAA 3GATA 4CN7A 4NQAB 3DZYD 4CN2C 3G9JA 3DZUD 3VD6C 3M9EA 2KAEA 3DZYA 3DZUA 3G6PA 3G9OA 4HC9A 4HN5A 4GATA 5E6DA 2VUSI 1R0OA 5EMQA 3G6RA
chains in the Genus database with same CATH superfamily
3DFXA 5CBYA 1CITA 1R4OA 5CC1A 3G6QA 3CBBA 2A66A 1YNWA 3G9PA 5EMPA 2DS5A 3G9IA 3G9MA 1R4IA 1GLUA 5EMCA 2VUTI 1GA5A 1BY4A 2NLLA 5L0MA 3G6TA 1HCQA 1KB4A 5GATA 5KRBB 1HLZA 5E6AA 1GNFA 5E6CA 4OV7A 3VEKC 2FF0A 4ONDA 4OLNA 3G8UA 2ENVA 1GDCA 2HANA 2VUUI 1RGDA 3FYLA 5E69A 2NLLB 2DS8A 1DSZA 1A6YA 4TNTA 3G97A 1GAUA 1GATA 4CN3D 4IQRA 5CC0A 2EBLA 1R0NA 4CN3A 4OORA 1R0OB 4CN5A 4AA6A 3G99A 5CBZA 3E00D 3E00A 2HANB 1YNWB 1KB2A 1DSZB 4HN6A 1LV3A 4TMAI 5E6BA 1R4RA 1R0NB 2C7AA 2DS6A 1LATA 5CBXA 1HRAA 2M9WA 3DFVC 1HCPA 1LO1A 2GATA 3G6UA 4HC7A 7GATA 1KB6A 3G27A 1RXRA 6GATA 3G8XA 4HCAA 2GDAA 3GATA 4CN7A 4NQAB 3DZYD 4CN2C 3G9JA 3DZUD 3VD6C 3M9EA 2KAEA 3DZYA 3DZUA 3G6PA 3G9OA 4HC9A 4HN5A 4GATA 5E6DA 2VUSI 1R0OA 5EMQA 3G6RA
chains in the Genus database with same CATH topology
3DFXA 5CBYA 1CITA 1R4OA 5CC1A 3G6QA 3CBBA 2A66A 1YNWA 3G9PA 5EMPA 3G9IA 3G9MA 1R4IA 1GLUA 5EMCA 2VUTI 1GA5A 1BY4A 2NLLA 5L0MA 3G6TA 1HCQA 1KB4A 5GATA 5KRBB 1HLZA 5E6AA 1GNFA 5E6CA 4OV7A 3VEKC 2FF0A 4ONDA 4OLNA 3G8UA 2ENVA 1GDCA 2HANA 2VUUI 1RGDA 3FYLA 5E69A 2NLLB 1DSZA 1A6YA 4TNTA 3G97A 1GAUA 1GATA 4CN3D 4IQRA 5CC0A 2EBLA 1R0NA 4CN3A 4OORA 1R0OB 4CN5A 4AA6A 3G99A 5CBZA 3E00D 3E00A 2HANB 1YNWB 1KB2A 1DSZB 4HN6A 1LV3A 4TMAI 5E6BA 1R4RA 1R0NB 2C7AA 1LATA 5CBXA 1HRAA 2M9WA 3DFVC 1HCPA 1LO1A 2GATA 3G6UA 4HC7A 7GATA 1KB6A 1RXRA 6GATA 3G8XA 4HCAA 2GDAA 3GATA 4CN7A 4NQAB 3DZYD 4CN2C 3G9JA 3DZUD 3VD6C 3M9EA 2KAEA 3DZYA 3DZUA 3G6PA 3G9OA 4HC9A 4HN5A 4GATA 5E6DA 2VUSI 1R0OA 5EMQA 3G6RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DFX A;  5CBY A;  1CIT A;  1R4O A;  5CC1 A;  3G6Q A;  3CBB A;  2A66 A;  1YNW A;  3G9P A;  5EMP A;  3G9I A;  3G9M A;  1R4I A;  1GLU A;  5EMC A;  2VUT I;  1GA5 A;  1BY4 A;  2NLL A;  5L0M A;  3G6T A;  1HCQ A;  1KB4 A;  5GAT A;  5KRB B;  1HLZ A;  5E6A A;  1GNF A;  5E6C A;  4OV7 A;  3VEK C;  2FF0 A;  4OND A;  4OLN A;  3G8U A;  2ENV A;  1GDC A;  2HAN A;  2VUU I;  1RGD A;  3FYL A;  5E69 A;  2NLL B;  1DSZ A;  1A6Y A;  4TNT A;  3G97 A;  1GAU A;  1GAT A;  4CN3 D;  4IQR A;  5CC0 A;  2EBL A;  1R0N A;  4CN3 A;  4OOR A;  1R0O B;  4CN5 A;  4AA6 A;  3G99 A;  5CBZ A;  3E00 D;  3E00 A;  2HAN B;  1YNW B;  1KB2 A;  1DSZ B;  4HN6 A;  1LV3 A;  4TMA I;  5E6B A;  1R4R A;  1R0N B;  2C7A A;  1LAT A;  5CBX A;  1HRA A;  2M9W A;  3DFV C;  1HCP A;  1LO1 A;  2GAT A;  3G6U A;  4HC7 A;  7GAT A;  1KB6 A;  1RXR A;  6GAT A;  3G8X A;  4HCA A;  2GDA A;  3GAT A;  4CN7 A;  4NQA B;  3DZY D;  4CN2 C;  3G9J A;  3DZU D;  3VD6 C;  3M9E A;  2KAE A;  3DZY A;  3DZU A;  3G6P A;  3G9O A;  4HC9 A;  4HN5 A;  4GAT A;  5E6D A;  2VUS I;  1R0O A;  5EMQ A;  3G6R A; 
#chains in the Genus database with same CATH topology
 3DFX A;  5CBY A;  1CIT A;  1R4O A;  5CC1 A;  3G6Q A;  3CBB A;  2A66 A;  1YNW A;  3G9P A;  5EMP A;  2DS5 A;  3G9I A;  3G9M A;  1R4I A;  1GLU A;  5EMC A;  2VUT I;  1GA5 A;  1BY4 A;  2NLL A;  5L0M A;  3G6T A;  1HCQ A;  1KB4 A;  5GAT A;  5KRB B;  1HLZ A;  5E6A A;  1GNF A;  5E6C A;  4OV7 A;  3VEK C;  2FF0 A;  4OND A;  4OLN A;  3G8U A;  2ENV A;  1GDC A;  2HAN A;  2VUU I;  1RGD A;  3FYL A;  5E69 A;  2NLL B;  2DS8 A;  1DSZ A;  1A6Y A;  4TNT A;  3G97 A;  1GAU A;  1GAT A;  4CN3 D;  4IQR A;  5CC0 A;  2EBL A;  1R0N A;  4CN3 A;  4OOR A;  1R0O B;  4CN5 A;  4AA6 A;  3G99 A;  5CBZ A;  3E00 D;  3E00 A;  2HAN B;  1YNW B;  1KB2 A;  1DSZ B;  4HN6 A;  1LV3 A;  4TMA I;  5E6B A;  1R4R A;  1R0N B;  2C7A A;  2DS6 A;  1LAT A;  5CBX A;  1HRA A;  2M9W A;  3DFV C;  1HCP A;  1LO1 A;  2GAT A;  3G6U A;  4HC7 A;  7GAT A;  1KB6 A;  3G27 A;  1RXR A;  6GAT A;  3G8X A;  4HCA A;  2GDA A;  3GAT A;  4CN7 A;  4NQA B;  3DZY D;  4CN2 C;  3G9J A;  3DZU D;  3VD6 C;  3M9E A;  2KAE A;  3DZY A;  3DZU A;  3G6P A;  3G9O A;  4HC9 A;  4HN5 A;  4GAT A;  5E6D A;  2VUS I;  1R0O A;  5EMQ A;  3G6R A; 
#chains in the Genus database with same CATH homology
 3DFX A;  5CBY A;  1CIT A;  1R4O A;  5CC1 A;  3G6Q A;  3CBB A;  2A66 A;  1YNW A;  3G9P A;  5EMP A;  3G9I A;  3G9M A;  1R4I A;  1GLU A;  5EMC A;  2VUT I;  1GA5 A;  1BY4 A;  2NLL A;  5L0M A;  3G6T A;  1HCQ A;  1KB4 A;  5GAT A;  5KRB B;  1HLZ A;  5E6A A;  1GNF A;  5E6C A;  4OV7 A;  3VEK C;  2FF0 A;  4OND A;  4OLN A;  3G8U A;  2ENV A;  1GDC A;  2HAN A;  2VUU I;  1RGD A;  3FYL A;  5E69 A;  2NLL B;  1DSZ A;  1A6Y A;  4TNT A;  3G97 A;  1GAU A;  1GAT A;  4CN3 D;  4IQR A;  5CC0 A;  2EBL A;  1R0N A;  4CN3 A;  4OOR A;  1R0O B;  4CN5 A;  4AA6 A;  3G99 A;  5CBZ A;  3E00 D;  3E00 A;  2HAN B;  1YNW B;  1KB2 A;  1DSZ B;  4HN6 A;  1LV3 A;  4TMA I;  5E6B A;  1R4R A;  1R0N B;  2C7A A;  1LAT A;  5CBX A;  1HRA A;  2M9W A;  3DFV C;  1HCP A;  1LO1 A;  2GAT A;  3G6U A;  4HC7 A;  7GAT A;  1KB6 A;  1RXR A;  6GAT A;  3G8X A;  4HCA A;  2GDA A;  3GAT A;  4CN7 A;  4NQA B;  3DZY D;  4CN2 C;  3G9J A;  3DZU D;  3VD6 C;  3M9E A;  2KAE A;  3DZY A;  3DZU A;  3G6P A;  3G9O A;  4HC9 A;  4HN5 A;  4GAT A;  5E6D A;  2VUS I;  1R0O A;  5EMQ A;  3G6R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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