1IO4D

Crystal structure of runx-1/aml1/cbfalpha runt domain-cbfbeta core domain heterodimer and c/ebpbeta bzip homodimer bound to a dna fragment from the csf-1r promoter
Total Genus 27
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
139
structure length
128
Chain Sequence
PRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQTRFQNACRDGRSEIAFVATGTNLSLQFFPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLHRLDGMGCLEFDEERAQQEDALAQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta.
pubmed doi rcsb
molecule keywords CSF-1R PROMOTER
molecule tags Transcription/dna
source organism Homo sapiens
total genus 27
structure length 128
sequence length 139
ec nomenclature
pdb deposition date 2001-01-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.250.10 Mainly Beta Beta Barrel Polyomavirus Enhancer Binding Protein 2; Chain: A; Core binding factor, beta subunit 1io4D00
3WTXB 1E50B 3WTYB 3WTTB 3WTUB 1H9DB 3WTVB 3WTWB 1IO4D 1ILFA 4N9F0 3WTSB 2JHBA 1CL3A
chains in the Genus database with same CATH superfamily
3WTXB 1E50B 3WTYB 3WTTB 3WTUB 1H9DB 3WTVB 3WTWB 1IO4D 1ILFA 4N9F0 3WTSB 2JHBA 1CL3A
chains in the Genus database with same CATH topology
3WTXB 1E50B 3WTYB 3WTTB 3WTUB 1H9DB 3WTVB 3WTWB 1IO4D 1ILFA 4N9F0 3WTSB 2JHBA 1CL3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WTX B;  1E50 B;  3WTY B;  3WTT B;  3WTU B;  1H9D B;  3WTV B;  3WTW B;  1IO4 D;  1ILF A;  4N9F 0;  3WTS B;  2JHB A;  1CL3 A; 
#chains in the Genus database with same CATH topology
 3WTX B;  1E50 B;  3WTY B;  3WTT B;  3WTU B;  1H9D B;  3WTV B;  3WTW B;  1IO4 D;  1ILF A;  4N9F 0;  3WTS B;  2JHB A;  1CL3 A; 
#chains in the Genus database with same CATH homology
 3WTX B;  1E50 B;  3WTY B;  3WTT B;  3WTU B;  1H9D B;  3WTV B;  3WTW B;  1IO4 D;  1ILF A;  4N9F 0;  3WTS B;  2JHB A;  1CL3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...