1J1FA

Crystal structure of the rnase mc1 mutant n71t in complex with 5'-gmp
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
191
structure length
191
Chain Sequence
EFDSFWFVQQWPPAVCSFQKSGSCPGSGLRTFTIHGLWPQQSGTSLTNCPGSPFDITKISHLQSQLNTLWPTVLRANNQQFWSHEWTKHGTCSESTFNQAAYFKLAVDMRNNYDIIGALRPHAAGPNGRTKSRQAIKGFLKAKFGKFPGLRCRTDPQTKVSYLVEVVACFAQDGSTLIDCTRDTCGANFIF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of the Ribonuclease MC1 Mutants N71T and N71S in Complex with 5'-GMP: Structural Basis for Alterations in Substrate Specificity
pubmed doi rcsb
molecule keywords RIBONUCLEASE MC1
molecule tags Hydrolase
source organism Momordica charantia
total genus 58
structure length 191
sequence length 191
ec nomenclature ec 3.1.27.1: Transferred entry: 4.6.1.19.
pdb deposition date 2002-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00445 Ribonuclease_T2 Ribonuclease T2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.730.10 Alpha Beta Alpha-Beta Complex Ribonuclease Rh; Chain A Ribonuclease T2-like 1j1fA00
4DVNA 2PQXA 2Z70A 3T0OA 4DW5A 1BK7A 4DW4A 1UCAA 1IOOA 1BOLA 1UCDA 1IQQA 2EA1A 1J1FA 1IYBA 1UCCA 1UCGA 4DWCA 4DW3A 1VD3A 3TBJA 4DVLA 1VCZA 1J1GA 1JY5A 3D3ZA 4DW7A 4DVKA 1VD1A 4DWAA 1V9HA 1DIXA 2PQYA 1SGLA
chains in the Genus database with same CATH superfamily
4DVNA 2PQXA 2Z70A 3T0OA 4DW5A 1BK7A 4DW4A 1UCAA 1IOOA 1BOLA 1UCDA 1IQQA 2EA1A 1J1FA 1IYBA 1UCCA 1UCGA 4DWCA 4DW3A 1VD3A 3TBJA 4DVLA 1VCZA 1J1GA 1JY5A 3D3ZA 4DW7A 4DVKA 1VD1A 4DWAA 1V9HA 1DIXA 2PQYA 1SGLA
chains in the Genus database with same CATH topology
4DVNA 2PQXA 2Z70A 3T0OA 4DW5A 1BK7A 4DW4A 1UCAA 1IOOA 1BOLA 1UCDA 1IQQA 2EA1A 1J1FA 1IYBA 1UCCA 1UCGA 4DWCA 4DW3A 1VD3A 3TBJA 4DVLA 1VCZA 1J1GA 1JY5A 3D3ZA 4DW7A 4DVKA 1VD1A 4DWAA 1V9HA 1DIXA 2PQYA 1SGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DVN A;  2PQX A;  2Z70 A;  3T0O A;  4DW5 A;  1BK7 A;  4DW4 A;  1UCA A;  1IOO A;  1BOL A;  1UCD A;  1IQQ A;  2EA1 A;  1J1F A;  1IYB A;  1UCC A;  1UCG A;  4DWC A;  4DW3 A;  1VD3 A;  3TBJ A;  4DVL A;  1VCZ A;  1J1G A;  1JY5 A;  3D3Z A;  4DW7 A;  4DVK A;  1VD1 A;  4DWA A;  1V9H A;  1DIX A;  2PQY A;  1SGL A; 
#chains in the Genus database with same CATH topology
 4DVN A;  2PQX A;  2Z70 A;  3T0O A;  4DW5 A;  1BK7 A;  4DW4 A;  1UCA A;  1IOO A;  1BOL A;  1UCD A;  1IQQ A;  2EA1 A;  1J1F A;  1IYB A;  1UCC A;  1UCG A;  4DWC A;  4DW3 A;  1VD3 A;  3TBJ A;  4DVL A;  1VCZ A;  1J1G A;  1JY5 A;  3D3Z A;  4DW7 A;  4DVK A;  1VD1 A;  4DWA A;  1V9H A;  1DIX A;  2PQY A;  1SGL A; 
#chains in the Genus database with same CATH homology
 4DVN A;  2PQX A;  2Z70 A;  3T0O A;  4DW5 A;  1BK7 A;  4DW4 A;  1UCA A;  1IOO A;  1BOL A;  1UCD A;  1IQQ A;  2EA1 A;  1J1F A;  1IYB A;  1UCC A;  1UCG A;  4DWC A;  4DW3 A;  1VD3 A;  3TBJ A;  4DVL A;  1VCZ A;  1J1G A;  1JY5 A;  3D3Z A;  4DW7 A;  4DVK A;  1VD1 A;  4DWA A;  1V9H A;  1DIX A;  2PQY A;  1SGL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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