3TBJA

The 1.7a crystal structure of actibind a t2 ribonucleases as antitumorigenic agents
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
TIDTCSSDSPLSCQTDNEASCCFNSPGGSLLQTQFWDYDPSDGPSDSWTIHGLWPDNCDGTYQEYCDESREYSNITSILEAQNRTELLSYMKEYWPDYEGADEDESFWEHEWNKHGTCINTIEPSCYTDYYAQEEVGDFFQQVVDLFKTLDSYTALSDAGITPSEDATYKLSDIEDALAAIHDGYPPYVGCEDGALSQLYYYFNVKGSAIGGTYVASERLEDSNCKDSGIKYPPKYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Actibind
publication title The 1.8 A crystal structure of ACTIBIND suggests a mode of action for T2 ribonucleases as antitumorigenic agents.
pubmed doi rcsb
total genus 74
structure length 237
sequence length 237
ec nomenclature
pdb deposition date 2011-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00445 Ribonuclease_T2 Ribonuclease T2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.730.10 Alpha Beta Alpha-Beta Complex Ribonuclease Rh; Chain A Ribonuclease T2-like 3tbjA00
1VD3A 1VCZA 4DWCA 2PQXA 3T0OA 3TBJA 4DWAA 4DVLA 1BK7A 4DW4A 1IOOA 1UCCA 1SGLA 2PQYA 1UCGA 1UCAA 1BOLA 1IQQA 1JY5A 4DW3A 2EA1A 3D3ZA 1UCDA 2Z70A 1IYBA 4DW5A 4DW7A 1VD1A 4DVNA 1J1GA 1DIXA 1V9HA 4DVKA 1J1FA
chains in the Genus database with same CATH superfamily
1VD3A 1VCZA 4DWCA 2PQXA 3T0OA 3TBJA 4DWAA 4DVLA 1BK7A 4DW4A 1IOOA 1UCCA 1SGLA 2PQYA 1UCGA 1UCAA 1BOLA 1IQQA 1JY5A 4DW3A 2EA1A 3D3ZA 1UCDA 2Z70A 1IYBA 4DW5A 4DW7A 1VD1A 4DVNA 1J1GA 1DIXA 1V9HA 4DVKA 1J1FA
chains in the Genus database with same CATH topology
1VD3A 1VCZA 4DWCA 2PQXA 3T0OA 3TBJA 4DWAA 4DVLA 1BK7A 4DW4A 1IOOA 1UCCA 1SGLA 2PQYA 1UCGA 1UCAA 1BOLA 1IQQA 1JY5A 4DW3A 2EA1A 3D3ZA 1UCDA 2Z70A 1IYBA 4DW5A 4DW7A 1VD1A 4DVNA 1J1GA 1DIXA 1V9HA 4DVKA 1J1FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VD3 A;  1VCZ A;  4DWC A;  2PQX A;  3T0O A;  3TBJ A;  4DWA A;  4DVL A;  1BK7 A;  4DW4 A;  1IOO A;  1UCC A;  1SGL A;  2PQY A;  1UCG A;  1UCA A;  1BOL A;  1IQQ A;  1JY5 A;  4DW3 A;  2EA1 A;  3D3Z A;  1UCD A;  2Z70 A;  1IYB A;  4DW5 A;  4DW7 A;  1VD1 A;  4DVN A;  1J1G A;  1DIX A;  1V9H A;  4DVK A;  1J1F A; 
#chains in the Genus database with same CATH topology
 1VD3 A;  1VCZ A;  4DWC A;  2PQX A;  3T0O A;  3TBJ A;  4DWA A;  4DVL A;  1BK7 A;  4DW4 A;  1IOO A;  1UCC A;  1SGL A;  2PQY A;  1UCG A;  1UCA A;  1BOL A;  1IQQ A;  1JY5 A;  4DW3 A;  2EA1 A;  3D3Z A;  1UCD A;  2Z70 A;  1IYB A;  4DW5 A;  4DW7 A;  1VD1 A;  4DVN A;  1J1G A;  1DIX A;  1V9H A;  4DVK A;  1J1F A; 
#chains in the Genus database with same CATH homology
 1VD3 A;  1VCZ A;  4DWC A;  2PQX A;  3T0O A;  3TBJ A;  4DWA A;  4DVL A;  1BK7 A;  4DW4 A;  1IOO A;  1UCC A;  1SGL A;  2PQY A;  1UCG A;  1UCA A;  1BOL A;  1IQQ A;  1JY5 A;  4DW3 A;  2EA1 A;  3D3Z A;  1UCD A;  2Z70 A;  1IYB A;  4DW5 A;  4DW7 A;  1VD1 A;  4DVN A;  1J1G A;  1DIX A;  1V9H A;  4DVK A;  1J1F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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