1MR1C

Crystal structure of a smad4-ski complex
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
97
structure length
97
Chain Sequence
SHMRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein
molecule keywords Mothers against decapentaplegic homolog 4
publication title Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski: Insights on Ski-mediated Repression of TGF-beta Signaling
pubmed doi rcsb
source organism Homo sapiens
total genus 21
structure length 97
sequence length 97
chains with identical sequence D
ec nomenclature
pdb deposition date 2002-09-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.390.10 Alpha Beta Roll SAND domain SAND domain-like 1mr1C00
1UFNA 5C4VB 1OQJA 1MR1C 1H5PA
chains in the Genus database with same CATH superfamily
1UFNA 5C4VB 1OQJA 1MR1C 1H5PA
chains in the Genus database with same CATH topology
1UFNA 5C4VB 1OQJA 1MR1C 1H5PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UFN A;  5C4V B;  1OQJ A;  1MR1 C;  1H5P A; 
#chains in the Genus database with same CATH topology
 1UFN A;  5C4V B;  1OQJ A;  1MR1 C;  1H5P A; 
#chains in the Genus database with same CATH homology
 1UFN A;  5C4V B;  1OQJ A;  1MR1 C;  1H5P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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