1YNWA

Crystal structure of vitamin d receptor and 9-cis retinoic acid receptor dna-binding domains bound to a dr3 response element
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
96
structure length
96
Chain Sequence
RNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCAANGDCRITKDNRRACQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of RXR-VDR interactions on DR3 DNA
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-d(*TP*TP*AP*GP*GP*TP*CP*AP*CP*GP*AP*AP*GP*GP*TP*CP*AP*A)-
total genus 22
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2005-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 1ynwA00
4OV7A 1RXRA 5EMQA 3M9EA 1RGDA 3G6QA 1R4IA 1R0OB 5CBZA 5E6AA 5GATA 1HCPA 3G8XA 3DZUD 1R0OA 2GATA 3DZYA 3VEKC 1HRAA 1LATA 3G97A 3CBBA 1BY4A 2C7AA 4HN5A 3FYLA 4AA6A 2EBLA 4HCAA 1LO1A 4IQRA 4NQAB 4CN3A 3E00A 2VUSI 2VUUI 4HC7A 5E6CA 3G9IA 1KB2A 1GATA 2ENVA 4TNTA 3G9PA 1HLZA 1R4RA 4GATA 5CBXA 3GATA 2KAEA 3G8UA 1R4OA 4OLNA 2FF0A 7GATA 1GNFA 5KRBB 4HN6A 6GATA 5E69A 1GDCA 2HANB 2A66A 1DSZB 4HC9A 2HANA 3DFXA 1HCQA 1DSZA 5L0MA 2NLLB 3G9JA 3DZUA 3DZYD 2NLLA 1CITA 5EMCA 3G6TA 4CN7A 3VD6C 1YNWB 1GAUA 5E6DA 5CC0A 5E6BA 3G6RA 1YNWA 4OORA 5CBYA 3G99A 5CC1A 4CN3D 1LV3A 1KB6A 3E00D 4CN2C 5EMPA 2VUTI 1GA5A 3G9OA 4ONDA 3DFVC 3G6PA 1KB4A 1R0NB 1A6YA 2GDAA 3G6UA 4TMAI 4CN5A 1R0NA 3G9MA 1GLUA 2M9WA
chains in the Genus database with same CATH superfamily
4OV7A 1RXRA 5EMQA 3M9EA 1RGDA 3G6QA 1R4IA 1R0OB 5CBZA 5E6AA 5GATA 1HCPA 3G8XA 3DZUD 1R0OA 2GATA 3DZYA 3VEKC 1HRAA 1LATA 3G97A 3CBBA 1BY4A 3G27A 2C7AA 4HN5A 3FYLA 4AA6A 2EBLA 4HCAA 1LO1A 4IQRA 4NQAB 4CN3A 3E00A 2VUSI 2VUUI 4HC7A 5E6CA 3G9IA 1KB2A 1GATA 2ENVA 4TNTA 3G9PA 1HLZA 1R4RA 4GATA 5CBXA 3GATA 2KAEA 3G8UA 1R4OA 4OLNA 2FF0A 7GATA 1GNFA 2DS5A 5KRBB 4HN6A 6GATA 5E69A 1GDCA 2HANB 2A66A 1DSZB 4HC9A 2HANA 3DFXA 1HCQA 1DSZA 5L0MA 2NLLB 3G9JA 3DZUA 3DZYD 2NLLA 1CITA 5EMCA 3G6TA 4CN7A 3VD6C 1YNWB 1GAUA 5E6DA 5CC0A 5E6BA 3G6RA 1YNWA 4OORA 5CBYA 3G99A 5CC1A 2DS6A 4CN3D 1LV3A 1KB6A 3E00D 2DS8A 5EMPA 2VUTI 4CN2C 1GA5A 3G9OA 4ONDA 3DFVC 3G6PA 1KB4A 1R0NB 1A6YA 2GDAA 3G6UA 4TMAI 4CN5A 1R0NA 3G9MA 1GLUA 2M9WA
chains in the Genus database with same CATH topology
4OV7A 1RXRA 5EMQA 3M9EA 1RGDA 3G6QA 1R4IA 1R0OB 5CBZA 5E6AA 5GATA 1HCPA 3G8XA 3DZUD 1R0OA 2GATA 3DZYA 3VEKC 1HRAA 1LATA 3G97A 3CBBA 1BY4A 2C7AA 4HN5A 3FYLA 4AA6A 2EBLA 4HCAA 1LO1A 4IQRA 4NQAB 4CN3A 3E00A 2VUSI 2VUUI 4HC7A 5E6CA 3G9IA 1KB2A 1GATA 2ENVA 4TNTA 3G9PA 1HLZA 1R4RA 4GATA 5CBXA 3GATA 2KAEA 3G8UA 1R4OA 4OLNA 2FF0A 7GATA 1GNFA 5KRBB 4HN6A 6GATA 5E69A 1GDCA 2HANB 2A66A 1DSZB 4HC9A 2HANA 3DFXA 1HCQA 1DSZA 5L0MA 2NLLB 3G9JA 3DZUA 3DZYD 2NLLA 1CITA 5EMCA 3G6TA 4CN7A 3VD6C 1YNWB 1GAUA 5E6DA 5CC0A 5E6BA 3G6RA 1YNWA 4OORA 5CBYA 3G99A 5CC1A 4CN3D 1LV3A 1KB6A 3E00D 4CN2C 5EMPA 2VUTI 1GA5A 3G9OA 4ONDA 3DFVC 3G6PA 1KB4A 1R0NB 1A6YA 2GDAA 3G6UA 4TMAI 4CN5A 1R0NA 3G9MA 1GLUA 2M9WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OV7 A;  1RXR A;  5EMQ A;  3M9E A;  1RGD A;  3G6Q A;  1R4I A;  1R0O B;  5CBZ A;  5E6A A;  5GAT A;  1HCP A;  3G8X A;  3DZU D;  1R0O A;  2GAT A;  3DZY A;  3VEK C;  1HRA A;  1LAT A;  3G97 A;  3CBB A;  1BY4 A;  2C7A A;  4HN5 A;  3FYL A;  4AA6 A;  2EBL A;  4HCA A;  1LO1 A;  4IQR A;  4NQA B;  4CN3 A;  3E00 A;  2VUS I;  2VUU I;  4HC7 A;  5E6C A;  3G9I A;  1KB2 A;  1GAT A;  2ENV A;  4TNT A;  3G9P A;  1HLZ A;  1R4R A;  4GAT A;  5CBX A;  3GAT A;  2KAE A;  3G8U A;  1R4O A;  4OLN A;  2FF0 A;  7GAT A;  1GNF A;  5KRB B;  4HN6 A;  6GAT A;  5E69 A;  1GDC A;  2HAN B;  2A66 A;  1DSZ B;  4HC9 A;  2HAN A;  3DFX A;  1HCQ A;  1DSZ A;  5L0M A;  2NLL B;  3G9J A;  3DZU A;  3DZY D;  2NLL A;  1CIT A;  5EMC A;  3G6T A;  4CN7 A;  3VD6 C;  1YNW B;  1GAU A;  5E6D A;  5CC0 A;  5E6B A;  3G6R A;  1YNW A;  4OOR A;  5CBY A;  3G99 A;  5CC1 A;  4CN3 D;  1LV3 A;  1KB6 A;  3E00 D;  4CN2 C;  5EMP A;  2VUT I;  1GA5 A;  3G9O A;  4OND A;  3DFV C;  3G6P A;  1KB4 A;  1R0N B;  1A6Y A;  2GDA A;  3G6U A;  4TMA I;  4CN5 A;  1R0N A;  3G9M A;  1GLU A;  2M9W A; 
#chains in the Genus database with same CATH topology
 4OV7 A;  1RXR A;  5EMQ A;  3M9E A;  1RGD A;  3G6Q A;  1R4I A;  1R0O B;  5CBZ A;  5E6A A;  5GAT A;  1HCP A;  3G8X A;  3DZU D;  1R0O A;  2GAT A;  3DZY A;  3VEK C;  1HRA A;  1LAT A;  3G97 A;  3CBB A;  1BY4 A;  3G27 A;  2C7A A;  4HN5 A;  3FYL A;  4AA6 A;  2EBL A;  4HCA A;  1LO1 A;  4IQR A;  4NQA B;  4CN3 A;  3E00 A;  2VUS I;  2VUU I;  4HC7 A;  5E6C A;  3G9I A;  1KB2 A;  1GAT A;  2ENV A;  4TNT A;  3G9P A;  1HLZ A;  1R4R A;  4GAT A;  5CBX A;  3GAT A;  2KAE A;  3G8U A;  1R4O A;  4OLN A;  2FF0 A;  7GAT A;  1GNF A;  2DS5 A;  5KRB B;  4HN6 A;  6GAT A;  5E69 A;  1GDC A;  2HAN B;  2A66 A;  1DSZ B;  4HC9 A;  2HAN A;  3DFX A;  1HCQ A;  1DSZ A;  5L0M A;  2NLL B;  3G9J A;  3DZU A;  3DZY D;  2NLL A;  1CIT A;  5EMC A;  3G6T A;  4CN7 A;  3VD6 C;  1YNW B;  1GAU A;  5E6D A;  5CC0 A;  5E6B A;  3G6R A;  1YNW A;  4OOR A;  5CBY A;  3G99 A;  5CC1 A;  2DS6 A;  4CN3 D;  1LV3 A;  1KB6 A;  3E00 D;  2DS8 A;  5EMP A;  2VUT I;  4CN2 C;  1GA5 A;  3G9O A;  4OND A;  3DFV C;  3G6P A;  1KB4 A;  1R0N B;  1A6Y A;  2GDA A;  3G6U A;  4TMA I;  4CN5 A;  1R0N A;  3G9M A;  1GLU A;  2M9W A; 
#chains in the Genus database with same CATH homology
 4OV7 A;  1RXR A;  5EMQ A;  3M9E A;  1RGD A;  3G6Q A;  1R4I A;  1R0O B;  5CBZ A;  5E6A A;  5GAT A;  1HCP A;  3G8X A;  3DZU D;  1R0O A;  2GAT A;  3DZY A;  3VEK C;  1HRA A;  1LAT A;  3G97 A;  3CBB A;  1BY4 A;  2C7A A;  4HN5 A;  3FYL A;  4AA6 A;  2EBL A;  4HCA A;  1LO1 A;  4IQR A;  4NQA B;  4CN3 A;  3E00 A;  2VUS I;  2VUU I;  4HC7 A;  5E6C A;  3G9I A;  1KB2 A;  1GAT A;  2ENV A;  4TNT A;  3G9P A;  1HLZ A;  1R4R A;  4GAT A;  5CBX A;  3GAT A;  2KAE A;  3G8U A;  1R4O A;  4OLN A;  2FF0 A;  7GAT A;  1GNF A;  5KRB B;  4HN6 A;  6GAT A;  5E69 A;  1GDC A;  2HAN B;  2A66 A;  1DSZ B;  4HC9 A;  2HAN A;  3DFX A;  1HCQ A;  1DSZ A;  5L0M A;  2NLL B;  3G9J A;  3DZU A;  3DZY D;  2NLL A;  1CIT A;  5EMC A;  3G6T A;  4CN7 A;  3VD6 C;  1YNW B;  1GAU A;  5E6D A;  5CC0 A;  5E6B A;  3G6R A;  1YNW A;  4OOR A;  5CBY A;  3G99 A;  5CC1 A;  4CN3 D;  1LV3 A;  1KB6 A;  3E00 D;  4CN2 C;  5EMP A;  2VUT I;  1GA5 A;  3G9O A;  4OND A;  3DFV C;  3G6P A;  1KB4 A;  1R0N B;  1A6Y A;  2GDA A;  3G6U A;  4TMA I;  4CN5 A;  1R0N A;  3G9M A;  1GLU A;  2M9W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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