1YNWB

Crystal structure of vitamin d receptor and 9-cis retinoic acid receptor dna-binding domains bound to a dr3 response element
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
73
structure length
73
Chain Sequence
ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural analysis of RXR-VDR interactions on DR3 DNA
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-d(*TP*TP*AP*GP*GP*TP*CP*AP*CP*GP*AP*AP*GP*GP*TP*CP*AP*A)-
total genus 17
structure length 73
sequence length 73
ec nomenclature
pdb deposition date 2005-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 1ynwB00
5CC0A 3DZYD 3VEKC 2GATA 1R4IA 1DSZB 3G6TA 2FF0A 3G6QA 1BY4A 3G9IA 3DZUD 1HCPA 4CN7A 5E6AA 4IQRA 3G97A 1KB6A 1R0NB 1RXRA 6GATA 5EMPA 1HLZA 2KAEA 1LATA 5EMQA 4HN6A 3G8XA 2HANB 5E6DA 4HN5A 1R0NA 1R4RA 1YNWA 3DFXA 4CN5A 4HCAA 4NQAB 1R4OA 2NLLA 4CN3A 4AA6A 7GATA 3E00A 3G6RA 2GDAA 3G6PA 1DSZA 1LV3A 3G8UA 1GLUA 2ENVA 4OLNA 2VUSI 3GATA 4ONDA 3G9JA 3G99A 3M9EA 1KB2A 1KB4A 1R0OB 1GA5A 3G6UA 3DFVC 2VUUI 5L0MA 4TMAI 3G9PA 2HANA 4OV7A 1GDCA 1HRAA 4TNTA 3CBBA 5CBZA 5E69A 5GATA 3FYLA 5CC1A 1GAUA 1GATA 4HC7A 3G9OA 3DZYA 1HCQA 1RGDA 1GNFA 2M9WA 3G9MA 5KRBB 5E6CA 3DZUA 1LO1A 4HC9A 1R0OA 5CBYA 2C7AA 4CN2C 5EMCA 4OORA 2EBLA 4CN3D 3VD6C 3E00D 1YNWB 5E6BA 2A66A 2NLLB 2VUTI 5CBXA 4GATA 1A6YA 1CITA
chains in the Genus database with same CATH superfamily
5CC0A 3DZYD 3VEKC 2GATA 1R4IA 1DSZB 3G6TA 2FF0A 3G6QA 1BY4A 3G9IA 3DZUD 1HCPA 4CN7A 5E6AA 4IQRA 3G97A 1KB6A 1R0NB 1RXRA 6GATA 5EMPA 1HLZA 2KAEA 1LATA 5EMQA 4HN6A 3G8XA 2HANB 5E6DA 4HN5A 1R0NA 1R4RA 1YNWA 3DFXA 4CN5A 4HCAA 4NQAB 1R4OA 2NLLA 4CN3A 4AA6A 7GATA 3E00A 3G6RA 2GDAA 2DS8A 3G6PA 1DSZA 1LV3A 3G8UA 1GLUA 2ENVA 4OLNA 2VUSI 2DS6A 3GATA 4ONDA 3G9JA 3G99A 3M9EA 1KB2A 1KB4A 1R0OB 1GA5A 3G6UA 3DFVC 2VUUI 2DS5A 5L0MA 4TMAI 3G9PA 2HANA 4OV7A 1GDCA 1HRAA 4TNTA 3CBBA 5CBZA 5E69A 5GATA 3FYLA 5CC1A 1GAUA 1GATA 4HC7A 3G9OA 3DZYA 1HCQA 1RGDA 1GNFA 2M9WA 3G9MA 5KRBB 5E6CA 3G27A 3DZUA 1LO1A 4HC9A 1R0OA 5CBYA 2C7AA 4CN2C 5EMCA 4OORA 2EBLA 4CN3D 3VD6C 3E00D 1YNWB 5E6BA 2A66A 2NLLB 2VUTI 5CBXA 4GATA 1A6YA 1CITA
chains in the Genus database with same CATH topology
5CC0A 3DZYD 3VEKC 2GATA 1R4IA 1DSZB 3G6TA 2FF0A 3G6QA 1BY4A 3G9IA 3DZUD 1HCPA 4CN7A 5E6AA 4IQRA 3G97A 1KB6A 1R0NB 1RXRA 6GATA 5EMPA 1HLZA 2KAEA 1LATA 5EMQA 4HN6A 3G8XA 2HANB 5E6DA 4HN5A 1R0NA 1R4RA 1YNWA 3DFXA 4CN5A 4HCAA 4NQAB 1R4OA 2NLLA 4CN3A 4AA6A 7GATA 3E00A 3G6RA 2GDAA 3G6PA 1DSZA 1LV3A 3G8UA 1GLUA 2ENVA 4OLNA 2VUSI 3GATA 4ONDA 3G9JA 3G99A 3M9EA 1KB2A 1KB4A 1R0OB 1GA5A 3G6UA 3DFVC 2VUUI 5L0MA 4TMAI 3G9PA 2HANA 4OV7A 1GDCA 1HRAA 4TNTA 3CBBA 5CBZA 5E69A 5GATA 3FYLA 5CC1A 1GAUA 1GATA 4HC7A 3G9OA 3DZYA 1HCQA 1RGDA 1GNFA 2M9WA 3G9MA 5KRBB 5E6CA 3DZUA 1LO1A 4HC9A 1R0OA 5CBYA 2C7AA 4CN2C 5EMCA 4OORA 2EBLA 4CN3D 3VD6C 3E00D 1YNWB 5E6BA 2A66A 2NLLB 2VUTI 5CBXA 4GATA 1A6YA 1CITA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CC0 A;  3DZY D;  3VEK C;  2GAT A;  1R4I A;  1DSZ B;  3G6T A;  2FF0 A;  3G6Q A;  1BY4 A;  3G9I A;  3DZU D;  1HCP A;  4CN7 A;  5E6A A;  4IQR A;  3G97 A;  1KB6 A;  1R0N B;  1RXR A;  6GAT A;  5EMP A;  1HLZ A;  2KAE A;  1LAT A;  5EMQ A;  4HN6 A;  3G8X A;  2HAN B;  5E6D A;  4HN5 A;  1R0N A;  1R4R A;  1YNW A;  3DFX A;  4CN5 A;  4HCA A;  4NQA B;  1R4O A;  2NLL A;  4CN3 A;  4AA6 A;  7GAT A;  3E00 A;  3G6R A;  2GDA A;  3G6P A;  1DSZ A;  1LV3 A;  3G8U A;  1GLU A;  2ENV A;  4OLN A;  2VUS I;  3GAT A;  4OND A;  3G9J A;  3G99 A;  3M9E A;  1KB2 A;  1KB4 A;  1R0O B;  1GA5 A;  3G6U A;  3DFV C;  2VUU I;  5L0M A;  4TMA I;  3G9P A;  2HAN A;  4OV7 A;  1GDC A;  1HRA A;  4TNT A;  3CBB A;  5CBZ A;  5E69 A;  5GAT A;  3FYL A;  5CC1 A;  1GAU A;  1GAT A;  4HC7 A;  3G9O A;  3DZY A;  1HCQ A;  1RGD A;  1GNF A;  2M9W A;  3G9M A;  5KRB B;  5E6C A;  3DZU A;  1LO1 A;  4HC9 A;  1R0O A;  5CBY A;  2C7A A;  4CN2 C;  5EMC A;  4OOR A;  2EBL A;  4CN3 D;  3VD6 C;  3E00 D;  1YNW B;  5E6B A;  2A66 A;  2NLL B;  2VUT I;  5CBX A;  4GAT A;  1A6Y A;  1CIT A; 
#chains in the Genus database with same CATH topology
 5CC0 A;  3DZY D;  3VEK C;  2GAT A;  1R4I A;  1DSZ B;  3G6T A;  2FF0 A;  3G6Q A;  1BY4 A;  3G9I A;  3DZU D;  1HCP A;  4CN7 A;  5E6A A;  4IQR A;  3G97 A;  1KB6 A;  1R0N B;  1RXR A;  6GAT A;  5EMP A;  1HLZ A;  2KAE A;  1LAT A;  5EMQ A;  4HN6 A;  3G8X A;  2HAN B;  5E6D A;  4HN5 A;  1R0N A;  1R4R A;  1YNW A;  3DFX A;  4CN5 A;  4HCA A;  4NQA B;  1R4O A;  2NLL A;  4CN3 A;  4AA6 A;  7GAT A;  3E00 A;  3G6R A;  2GDA A;  2DS8 A;  3G6P A;  1DSZ A;  1LV3 A;  3G8U A;  1GLU A;  2ENV A;  4OLN A;  2VUS I;  2DS6 A;  3GAT A;  4OND A;  3G9J A;  3G99 A;  3M9E A;  1KB2 A;  1KB4 A;  1R0O B;  1GA5 A;  3G6U A;  3DFV C;  2VUU I;  2DS5 A;  5L0M A;  4TMA I;  3G9P A;  2HAN A;  4OV7 A;  1GDC A;  1HRA A;  4TNT A;  3CBB A;  5CBZ A;  5E69 A;  5GAT A;  3FYL A;  5CC1 A;  1GAU A;  1GAT A;  4HC7 A;  3G9O A;  3DZY A;  1HCQ A;  1RGD A;  1GNF A;  2M9W A;  3G9M A;  5KRB B;  5E6C A;  3G27 A;  3DZU A;  1LO1 A;  4HC9 A;  1R0O A;  5CBY A;  2C7A A;  4CN2 C;  5EMC A;  4OOR A;  2EBL A;  4CN3 D;  3VD6 C;  3E00 D;  1YNW B;  5E6B A;  2A66 A;  2NLL B;  2VUT I;  5CBX A;  4GAT A;  1A6Y A;  1CIT A; 
#chains in the Genus database with same CATH homology
 5CC0 A;  3DZY D;  3VEK C;  2GAT A;  1R4I A;  1DSZ B;  3G6T A;  2FF0 A;  3G6Q A;  1BY4 A;  3G9I A;  3DZU D;  1HCP A;  4CN7 A;  5E6A A;  4IQR A;  3G97 A;  1KB6 A;  1R0N B;  1RXR A;  6GAT A;  5EMP A;  1HLZ A;  2KAE A;  1LAT A;  5EMQ A;  4HN6 A;  3G8X A;  2HAN B;  5E6D A;  4HN5 A;  1R0N A;  1R4R A;  1YNW A;  3DFX A;  4CN5 A;  4HCA A;  4NQA B;  1R4O A;  2NLL A;  4CN3 A;  4AA6 A;  7GAT A;  3E00 A;  3G6R A;  2GDA A;  3G6P A;  1DSZ A;  1LV3 A;  3G8U A;  1GLU A;  2ENV A;  4OLN A;  2VUS I;  3GAT A;  4OND A;  3G9J A;  3G99 A;  3M9E A;  1KB2 A;  1KB4 A;  1R0O B;  1GA5 A;  3G6U A;  3DFV C;  2VUU I;  5L0M A;  4TMA I;  3G9P A;  2HAN A;  4OV7 A;  1GDC A;  1HRA A;  4TNT A;  3CBB A;  5CBZ A;  5E69 A;  5GAT A;  3FYL A;  5CC1 A;  1GAU A;  1GAT A;  4HC7 A;  3G9O A;  3DZY A;  1HCQ A;  1RGD A;  1GNF A;  2M9W A;  3G9M A;  5KRB B;  5E6C A;  3DZU A;  1LO1 A;  4HC9 A;  1R0O A;  5CBY A;  2C7A A;  4CN2 C;  5EMC A;  4OOR A;  2EBL A;  4CN3 D;  3VD6 C;  3E00 D;  1YNW B;  5E6B A;  2A66 A;  2NLL B;  2VUT I;  5CBX A;  4GAT A;  1A6Y A;  1CIT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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