1EVWA

L116a mutant of the homing endonuclease i-ppoi complexed to homing site dna.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
162
structure length
162
Chain Sequence
ALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYGVGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASHLCHNTRCHNPLHLCWESADDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATVAGPQQRGSHFVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Physarum polycephalum
molecule keywords DNA (5'-D(*TP*GP*GP*CP*TP*AP*CP*CP*TP*TP*AP*A)-3')
total genus 27
structure length 162
sequence length 162
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2000-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05551 zf-His_Me_endon Zinc-binding loop region of homing endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.75.10 Alpha Beta Alpha-Beta Complex Homing Intron 3 (I-Ppo) Encoded Endonuclease; Chain A Homing Intron 3 (I-ppo) Encoded Endonuclease; Chain A 1evwA00
1A74A 1CZ0A 1EVWA 1A73A 1CYQA 1EVXA 1IPPA 2O6MA
chains in the Genus database with same CATH superfamily
1U3EM 1A74A 1CZ0A 1EVWA 1CYQA 1A73A 1EVXA 1IPPA 2O6MA
chains in the Genus database with same CATH topology
1U3EM 1A74A 1CZ0A 1EVWA 1CYQA 1A73A 1EVXA 1IPPA 2O6MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A74 A;  1CZ0 A;  1EVW A;  1A73 A;  1CYQ A;  1EVX A;  1IPP A;  2O6M A; 
#chains in the Genus database with same CATH topology
 1U3E M;  1A74 A;  1CZ0 A;  1EVW A;  1CYQ A;  1A73 A;  1EVX A;  1IPP A;  2O6M A; 
#chains in the Genus database with same CATH homology
 1U3E M;  1A74 A;  1CZ0 A;  1EVW A;  1CYQ A;  1A73 A;  1EVX A;  1IPP A;  2O6M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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