2A26A

Crystal structure of the n-terminal, dimerization domain of siah interacting protein
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
48
structure length
48
Chain Sequence
HMASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Calcyclin-binding protein
total genus 21
structure length 48
sequence length 48
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2005-06-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.860.10 Few Secondary Structures Irregular DNA Excision Repair, Uvrb; Chain A UVR domain 2a26A01
2A26A 2LF0A 3PXGA 1YSMA 1E52A 1QOJA 4U1CA
chains in the Genus database with same CATH superfamily
3V1EA 1YZMA 2A26A 1Z0JB 3V1BA 3V1FA 3DKQA 3PXGA 3V1DA 1Z0KB 1YSMA 4U1CA 1E52A 1QOJA 3V1AA 3V1CA 2LF0A
chains in the Genus database with same CATH topology
2A26A 2LF0A 3PXGA 1YSMA 1E52A 1QOJA 4U1CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A26 A;  2LF0 A;  3PXG A;  1YSM A;  1E52 A;  1QOJ A;  4U1C A; 
#chains in the Genus database with same CATH topology
 3V1E A;  1YZM A;  2A26 A;  1Z0J B;  3V1B A;  3V1F A;  3DKQ A;  3PXG A;  3V1D A;  1Z0K B;  1YSM A;  4U1C A;  1E52 A;  1QOJ A;  3V1A A;  3V1C A;  2LF0 A; 
#chains in the Genus database with same CATH homology
 2A26 A;  2LF0 A;  3PXG A;  1YSM A;  1E52 A;  1QOJ A;  4U1C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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