2HANA

Structural basis of heterodimeric ecdysteroid receptor interaction with natural response element hsp27 gene promoter
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
78
structure length
78
Chain Sequence
KHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel DNA-binding element within the C-terminal extension of the nuclear receptor DNA-binding domain.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Drosophila melanogaster
molecule keywords 5'-D(*CP*AP*AP*GP*GP*GP*TP*TP*CP*AP*AP*TP*GP*CP*AP*CP*TP*TP*
total genus 19
structure length 78
sequence length 78
ec nomenclature
pdb deposition date 2006-06-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 2hanA00
5EMQA 3G6QA 1KB6A 5GATA 3DZYD 1LV3A 1GLUA 2EBLA 4OV7A 7GATA 5E6DA 2C7AA 1GDCA 2VUSI 3E00A 3DZUA 4TMAI 4HCAA 2HANB 3G9PA 3G9IA 3DZUD 3E00D 2NLLB 2M9WA 5E6AA 3G99A 1YNWA 4GATA 3M9EA 4CN3A 4HN5A 3G6RA 1BY4A 4CN3D 1LATA 4HC7A 1GATA 3G6UA 1DSZB 4CN7A 2GDAA 4CN2C 1R0NA 1CITA 1GA5A 1HRAA 5E69A 3G8UA 3VEKC 2FF0A 3FYLA 1RGDA 2ENVA 1R0OA 3CBBA 1R4OA 1HCPA 3G9OA 6GATA 5E6CA 4AA6A 3G9JA 2HANA 2NLLA 4HN6A 2VUUI 1GAUA 4TNTA 2KAEA 3G6TA 1KB2A 3GATA 5EMCA 1HLZA 4CN5A 1DSZA 1R0NB 2GATA 1GNFA 1HCQA 2A66A 5E6BA 4IQRA 3G97A 5CC0A 3G8XA 1KB4A 4OORA 3G6PA 3G9MA 3DFVC 1R0OB 4HC9A 1YNWB 4ONDA 1R4IA 4NQAB 1R4RA 2VUTI 1RXRA 3DFXA 4OLNA 5CBYA 5KRBB 5CBXA 5CC1A 5CBZA 1A6YA 3VD6C 1LO1A 5EMPA 5L0MA 3DZYA
chains in the Genus database with same CATH superfamily
5EMQA 3G6QA 1KB6A 5GATA 3DZYD 1LV3A 1GLUA 2EBLA 4OV7A 7GATA 5E6DA 3G27A 2C7AA 1GDCA 2VUSI 3E00A 3DZUA 4TMAI 4HCAA 2HANB 3G9PA 3G9IA 3DZUD 3E00D 2NLLB 2M9WA 5E6AA 3G99A 1YNWA 4GATA 3M9EA 4CN3A 4HN5A 3G6RA 1BY4A 4CN3D 1LATA 4HC7A 1GATA 3G6UA 1DSZB 4CN7A 2GDAA 4CN2C 1R0NA 1CITA 1GA5A 1HRAA 5E69A 3G8UA 3VEKC 2FF0A 3FYLA 1RGDA 2ENVA 1R0OA 3CBBA 2DS8A 1R4OA 1HCPA 3G9OA 6GATA 5E6CA 4AA6A 3G9JA 2HANA 2NLLA 4HN6A 2VUUI 1GAUA 4TNTA 2KAEA 3G6TA 1KB2A 3GATA 5EMCA 1HLZA 4CN5A 1DSZA 1R0NB 2GATA 1GNFA 1HCQA 2A66A 5E6BA 4IQRA 3G97A 5CC0A 2DS6A 3G8XA 4OORA 1KB4A 3G6PA 3G9MA 3DFVC 2DS5A 1R0OB 4HC9A 1YNWB 4ONDA 1R4IA 4NQAB 1R4RA 2VUTI 1RXRA 3DFXA 4OLNA 5CBYA 5KRBB 5CBXA 5CC1A 5CBZA 1A6YA 3VD6C 1LO1A 5EMPA 5L0MA 3DZYA
chains in the Genus database with same CATH topology
5EMQA 3G6QA 1KB6A 5GATA 3DZYD 1LV3A 1GLUA 2EBLA 4OV7A 7GATA 5E6DA 2C7AA 1GDCA 2VUSI 3E00A 3DZUA 4TMAI 4HCAA 2HANB 3G9PA 3G9IA 3DZUD 3E00D 2NLLB 2M9WA 5E6AA 3G99A 1YNWA 4GATA 3M9EA 4CN3A 4HN5A 3G6RA 1BY4A 4CN3D 1LATA 4HC7A 1GATA 3G6UA 1DSZB 4CN7A 2GDAA 4CN2C 1R0NA 1CITA 1GA5A 1HRAA 5E69A 3G8UA 3VEKC 2FF0A 3FYLA 1RGDA 2ENVA 1R0OA 3CBBA 1R4OA 1HCPA 3G9OA 6GATA 5E6CA 4AA6A 3G9JA 2HANA 2NLLA 4HN6A 2VUUI 1GAUA 4TNTA 2KAEA 3G6TA 1KB2A 3GATA 5EMCA 1HLZA 4CN5A 1DSZA 1R0NB 2GATA 1GNFA 1HCQA 2A66A 5E6BA 4IQRA 3G97A 5CC0A 3G8XA 1KB4A 4OORA 3G6PA 3G9MA 3DFVC 1R0OB 4HC9A 1YNWB 4ONDA 1R4IA 4NQAB 1R4RA 2VUTI 1RXRA 3DFXA 4OLNA 5CBYA 5KRBB 5CBXA 5CC1A 5CBZA 1A6YA 3VD6C 1LO1A 5EMPA 5L0MA 3DZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EMQ A;  3G6Q A;  1KB6 A;  5GAT A;  3DZY D;  1LV3 A;  1GLU A;  2EBL A;  4OV7 A;  7GAT A;  5E6D A;  2C7A A;  1GDC A;  2VUS I;  3E00 A;  3DZU A;  4TMA I;  4HCA A;  2HAN B;  3G9P A;  3G9I A;  3DZU D;  3E00 D;  2NLL B;  2M9W A;  5E6A A;  3G99 A;  1YNW A;  4GAT A;  3M9E A;  4CN3 A;  4HN5 A;  3G6R A;  1BY4 A;  4CN3 D;  1LAT A;  4HC7 A;  1GAT A;  3G6U A;  1DSZ B;  4CN7 A;  2GDA A;  4CN2 C;  1R0N A;  1CIT A;  1GA5 A;  1HRA A;  5E69 A;  3G8U A;  3VEK C;  2FF0 A;  3FYL A;  1RGD A;  2ENV A;  1R0O A;  3CBB A;  1R4O A;  1HCP A;  3G9O A;  6GAT A;  5E6C A;  4AA6 A;  3G9J A;  2HAN A;  2NLL A;  4HN6 A;  2VUU I;  1GAU A;  4TNT A;  2KAE A;  3G6T A;  1KB2 A;  3GAT A;  5EMC A;  1HLZ A;  4CN5 A;  1DSZ A;  1R0N B;  2GAT A;  1GNF A;  1HCQ A;  2A66 A;  5E6B A;  4IQR A;  3G97 A;  5CC0 A;  3G8X A;  1KB4 A;  4OOR A;  3G6P A;  3G9M A;  3DFV C;  1R0O B;  4HC9 A;  1YNW B;  4OND A;  1R4I A;  4NQA B;  1R4R A;  2VUT I;  1RXR A;  3DFX A;  4OLN A;  5CBY A;  5KRB B;  5CBX A;  5CC1 A;  5CBZ A;  1A6Y A;  3VD6 C;  1LO1 A;  5EMP A;  5L0M A;  3DZY A; 
#chains in the Genus database with same CATH topology
 5EMQ A;  3G6Q A;  1KB6 A;  5GAT A;  3DZY D;  1LV3 A;  1GLU A;  2EBL A;  4OV7 A;  7GAT A;  5E6D A;  3G27 A;  2C7A A;  1GDC A;  2VUS I;  3E00 A;  3DZU A;  4TMA I;  4HCA A;  2HAN B;  3G9P A;  3G9I A;  3DZU D;  3E00 D;  2NLL B;  2M9W A;  5E6A A;  3G99 A;  1YNW A;  4GAT A;  3M9E A;  4CN3 A;  4HN5 A;  3G6R A;  1BY4 A;  4CN3 D;  1LAT A;  4HC7 A;  1GAT A;  3G6U A;  1DSZ B;  4CN7 A;  2GDA A;  4CN2 C;  1R0N A;  1CIT A;  1GA5 A;  1HRA A;  5E69 A;  3G8U A;  3VEK C;  2FF0 A;  3FYL A;  1RGD A;  2ENV A;  1R0O A;  3CBB A;  2DS8 A;  1R4O A;  1HCP A;  3G9O A;  6GAT A;  5E6C A;  4AA6 A;  3G9J A;  2HAN A;  2NLL A;  4HN6 A;  2VUU I;  1GAU A;  4TNT A;  2KAE A;  3G6T A;  1KB2 A;  3GAT A;  5EMC A;  1HLZ A;  4CN5 A;  1DSZ A;  1R0N B;  2GAT A;  1GNF A;  1HCQ A;  2A66 A;  5E6B A;  4IQR A;  3G97 A;  5CC0 A;  2DS6 A;  3G8X A;  4OOR A;  1KB4 A;  3G6P A;  3G9M A;  3DFV C;  2DS5 A;  1R0O B;  4HC9 A;  1YNW B;  4OND A;  1R4I A;  4NQA B;  1R4R A;  2VUT I;  1RXR A;  3DFX A;  4OLN A;  5CBY A;  5KRB B;  5CBX A;  5CC1 A;  5CBZ A;  1A6Y A;  3VD6 C;  1LO1 A;  5EMP A;  5L0M A;  3DZY A; 
#chains in the Genus database with same CATH homology
 5EMQ A;  3G6Q A;  1KB6 A;  5GAT A;  3DZY D;  1LV3 A;  1GLU A;  2EBL A;  4OV7 A;  7GAT A;  5E6D A;  2C7A A;  1GDC A;  2VUS I;  3E00 A;  3DZU A;  4TMA I;  4HCA A;  2HAN B;  3G9P A;  3G9I A;  3DZU D;  3E00 D;  2NLL B;  2M9W A;  5E6A A;  3G99 A;  1YNW A;  4GAT A;  3M9E A;  4CN3 A;  4HN5 A;  3G6R A;  1BY4 A;  4CN3 D;  1LAT A;  4HC7 A;  1GAT A;  3G6U A;  1DSZ B;  4CN7 A;  2GDA A;  4CN2 C;  1R0N A;  1CIT A;  1GA5 A;  1HRA A;  5E69 A;  3G8U A;  3VEK C;  2FF0 A;  3FYL A;  1RGD A;  2ENV A;  1R0O A;  3CBB A;  1R4O A;  1HCP A;  3G9O A;  6GAT A;  5E6C A;  4AA6 A;  3G9J A;  2HAN A;  2NLL A;  4HN6 A;  2VUU I;  1GAU A;  4TNT A;  2KAE A;  3G6T A;  1KB2 A;  3GAT A;  5EMC A;  1HLZ A;  4CN5 A;  1DSZ A;  1R0N B;  2GAT A;  1GNF A;  1HCQ A;  2A66 A;  5E6B A;  4IQR A;  3G97 A;  5CC0 A;  3G8X A;  1KB4 A;  4OOR A;  3G6P A;  3G9M A;  3DFV C;  1R0O B;  4HC9 A;  1YNW B;  4OND A;  1R4I A;  4NQA B;  1R4R A;  2VUT I;  1RXR A;  3DFX A;  4OLN A;  5CBY A;  5KRB B;  5CBX A;  5CC1 A;  5CBZ A;  1A6Y A;  3VD6 C;  1LO1 A;  5EMP A;  5L0M A;  3DZY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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