2HW4A

Crystal structure of human phosphohistidine phosphatase
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
124
structure length
116
Chain Sequence
LYFQSMDLALIPDVDIDSDGVFKYVLIRVHSAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Structural genomics, hydrolase
molecule keywords 14 kDa phosphohistidine phosphatase
publication title First structure of a eukaryotic phosphohistidine phosphatase
pubmed doi rcsb
source organism Homo sapiens
total genus 38
structure length 116
sequence length 124
ec nomenclature ec 3.9.1.3: Phosphohistidine phosphatase.
pdb deposition date 2006-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05005 Ocnus Janus/Ocnus family (Ocnus)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.20.20 Alpha Beta 3-Layer(bba) Sandwich Pyruvoyl-Dependent Histidine Decarboxylase; Chain B Pyruvoyl-Dependent Histidine Decarboxylase; Chain B 2hw4A01
2HW4A 2OZWA 2AI6A 2OZXA 2NMMA
chains in the Genus database with same CATH superfamily
2HW4A 1IBVB 1MT1B 1IBTB 1PYAB 2AI6A 1IBWB 2OZWA 2QQCB 1IBUB 2QQDB 1N13B 2OZXA 2NMMA 2QQDC 1HQ6B 1N2MA
chains in the Genus database with same CATH topology
2HW4A 2OZWA 2AI6A 2OZXA 2NMMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HW4 A;  2OZW A;  2AI6 A;  2OZX A;  2NMM A; 
#chains in the Genus database with same CATH topology
 2HW4 A;  1IBV B;  1MT1 B;  1IBT B;  1PYA B;  2AI6 A;  1IBW B;  2OZW A;  2QQC B;  1IBU B;  2QQD B;  1N13 B;  2OZX A;  2NMM A;  2QQD C;  1HQ6 B;  1N2M A; 
#chains in the Genus database with same CATH homology
 2HW4 A;  2OZW A;  2AI6 A;  2OZX A;  2NMM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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