2KIJA

Solution structure of the actuator domain of the copper-transporting atpase atp7a
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
119
structure length
119
Chain Sequence
SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 22
structure length 119
sequence length 119
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-05-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.150.20 Mainly Beta Distorted Sandwich Calcium-transporting ATPase, cytoplasmic transduction domain A Calcium-transporting ATPase, cytoplasmic transduction domain A 2kijA00
3RFUA 2KIJA 4BBJA 2HC8A 4BYGA 4UMVA 4BEVA
chains in the Genus database with same CATH superfamily
4J2TA 3B9BA 4RETA 2ZBDA 2C8LA 3FPBA 2ZBEA 3NANA 3J7TA 4H1WA 2ZBGA 2AGVA 5AVVA 2OA0A 5A3QA 4XOUA 3N8GA 3AR4A 5AW2A 5AVSA 5AVZA 3AR7A 4UMVA 3WGVA 4UU1A 3AR8A 5AVTA 2HC8A 1WPGA 4KYTA 5AVYA 5AVRA 2C8KA 1IWOA 5AW7A 3W5AA 2EARA 1XP5A 3AR5A 5AVQA 3A3YA 2YFYA 3FPSA 5AW8A 3BA6A 4Y3UA 4YCLA 4HYTA 1T5TA 5AVWA 5AW0A 5A3RA 3TLMA 4BEWA 1T5SA 2C9MA 5AVXA 5AW4A 5A3SA 2EAUA 3B8EA 1SU4A 3N5KA 4XE5A 5AW9A 3RFUA 3W5CA 1VFPA 3AR2A 4RESA 3AR6A 3AR3A 3AR9A 5AW6A 3NAMA 3KDPA 3W5BA 2DQSA 2O9JA 2KIJA 2BY4A 2ZXEA 5AW3A 2ZBFA 4YCNA 4YCMA 5AVUA 2EATA 5AW5A 3B9RA 3NALA 4UU0A 4BEVA 3W5DA 2C88A 3WGUA 4BBJA 4BYGA 5AW1A 3FGOA
chains in the Genus database with same CATH topology
4J2TA 3B9BA 4RETA 2ZBDA 2C8LA 3FPBA 2ZBEA 3NANA 3J7TA 4H1WA 2ZBGA 2AGVA 5AVVA 2OA0A 5A3QA 4XOUA 3N8GA 3AR4A 5AW2A 5AVSA 5AVZA 3AR7A 4UMVA 3WGVA 4UU1A 3AR8A 5AVTA 2HC8A 1WPGA 4KYTA 5AVYA 5AVRA 2C8KA 1IWOA 5AW7A 3W5AA 2EARA 1XP5A 3AR5A 5AVQA 3A3YA 2YFYA 3FPSA 5AW8A 3BA6A 4Y3UA 4YCLA 4HYTA 1T5TA 5AVWA 5AW0A 5A3RA 3TLMA 4BEWA 1T5SA 2C9MA 5AVXA 5AW4A 5A3SA 2EAUA 3B8EA 1SU4A 3N5KA 4XE5A 5AW9A 3RFUA 3W5CA 1VFPA 3AR2A 4RESA 3AR6A 3AR3A 3AR9A 5AW6A 3NAMA 3KDPA 3W5BA 2DQSA 2O9JA 2KIJA 2BY4A 2ZXEA 5AW3A 2ZBFA 4YCNA 4YCMA 5AVUA 2EATA 5AW5A 3B9RA 3NALA 4UU0A 4BEVA 3W5DA 2C88A 3WGUA 4BBJA 4BYGA 5AW1A 3FGOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RFU A;  2KIJ A;  4BBJ A;  2HC8 A;  4BYG A;  4UMV A;  4BEV A; 
#chains in the Genus database with same CATH topology
 4J2T A;  3B9B A;  4RET A;  2ZBD A;  2C8L A;  3FPB A;  2ZBE A;  3NAN A;  3J7T A;  4H1W A;  2ZBG A;  2AGV A;  5AVV A;  2OA0 A;  5A3Q A;  4XOU A;  3N8G A;  3AR4 A;  5AW2 A;  5AVS A;  5AVZ A;  3AR7 A;  4UMV A;  3WGV A;  4UU1 A;  3AR8 A;  5AVT A;  2HC8 A;  1WPG A;  4KYT A;  5AVY A;  5AVR A;  2C8K A;  1IWO A;  5AW7 A;  3W5A A;  2EAR A;  1XP5 A;  3AR5 A;  5AVQ A;  3A3Y A;  2YFY A;  3FPS A;  5AW8 A;  3BA6 A;  4Y3U A;  4YCL A;  4HYT A;  1T5T A;  5AVW A;  5AW0 A;  5A3R A;  3TLM A;  4BEW A;  1T5S A;  2C9M A;  5AVX A;  5AW4 A;  5A3S A;  2EAU A;  3B8E A;  1SU4 A;  3N5K A;  4XE5 A;  5AW9 A;  3RFU A;  3W5C A;  1VFP A;  3AR2 A;  4RES A;  3AR6 A;  3AR3 A;  3AR9 A;  5AW6 A;  3NAM A;  3KDP A;  3W5B A;  2DQS A;  2O9J A;  2KIJ A;  2BY4 A;  2ZXE A;  5AW3 A;  2ZBF A;  4YCN A;  4YCM A;  5AVU A;  2EAT A;  5AW5 A;  3B9R A;  3NAL A;  4UU0 A;  4BEV A;  3W5D A;  2C88 A;  3WGU A;  4BBJ A;  4BYG A;  5AW1 A;  3FGO A; 
#chains in the Genus database with same CATH homology
 4J2T A;  3B9B A;  4RET A;  2ZBD A;  2C8L A;  3FPB A;  2ZBE A;  3NAN A;  3J7T A;  4H1W A;  2ZBG A;  2AGV A;  5AVV A;  2OA0 A;  5A3Q A;  4XOU A;  3N8G A;  3AR4 A;  5AW2 A;  5AVS A;  5AVZ A;  3AR7 A;  4UMV A;  3WGV A;  4UU1 A;  3AR8 A;  5AVT A;  2HC8 A;  1WPG A;  4KYT A;  5AVY A;  5AVR A;  2C8K A;  1IWO A;  5AW7 A;  3W5A A;  2EAR A;  1XP5 A;  3AR5 A;  5AVQ A;  3A3Y A;  2YFY A;  3FPS A;  5AW8 A;  3BA6 A;  4Y3U A;  4YCL A;  4HYT A;  1T5T A;  5AVW A;  5AW0 A;  5A3R A;  3TLM A;  4BEW A;  1T5S A;  2C9M A;  5AVX A;  5AW4 A;  5A3S A;  2EAU A;  3B8E A;  1SU4 A;  3N5K A;  4XE5 A;  5AW9 A;  3RFU A;  3W5C A;  1VFP A;  3AR2 A;  4RES A;  3AR6 A;  3AR3 A;  3AR9 A;  5AW6 A;  3NAM A;  3KDP A;  3W5B A;  2DQS A;  2O9J A;  2KIJ A;  2BY4 A;  2ZXE A;  5AW3 A;  2ZBF A;  4YCN A;  4YCM A;  5AVU A;  2EAT A;  5AW5 A;  3B9R A;  3NAL A;  4UU0 A;  4BEV A;  3W5D A;  2C88 A;  3WGU A;  4BBJ A;  4BYG A;  5AW1 A;  3FGO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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