2KIJA

Solution structure of the actuator domain of the copper-transporting atpase atp7a
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
119
structure length
119
Chain Sequence
SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords Copper-transporting ATPase 1
total genus 22
structure length 119
sequence length 119
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-05-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.150.20 Mainly Beta Distorted Sandwich Calcium-transporting ATPase, cytoplasmic transduction domain A Calcium-transporting ATPase, cytoplasmic transduction domain A 2kijA00
3RFUA 4BBJA 2KIJA 2HC8A 4UMVA 4BEVA 4BYGA
chains in the Genus database with same CATH superfamily
3AR3A 2EARA 4UU1A 5AW6A 2C9MA 2O9JA 2AGVA 3NANA 4BYGA 5AW1A 3AR2A 3AR6A 3AR7A 4HYTA 4BEVA 3W5DA 3AR5A 2DQSA 4YCMA 5AVZA 4H1WA 5AW4A 4Y3UA 1IWOA 3B8EA 4RETA 3A3YA 5AW9A 3TLMA 5AVYA 5AW8A 5AW7A 2HC8A 4XE5A 5AW0A 3NALA 3FGOA 1SU4A 3W5BA 2ZBDA 1T5SA 2ZBFA 3N8GA 5AVUA 4XOUA 5AVQA 4UU0A 5A3RA 3FPBA 1T5TA 2EAUA 4KYTA 1VFPA 3AR9A 5AVRA 3B9RA 3WGUA 5AVWA 2OA0A 2C8LA 5AVTA 3B9BA 1WPGA 3RFUA 5AW3A 1XP5A 3FPSA 4YCNA 2EATA 2ZBEA 3W5CA 5A3SA 4UMVA 5AW5A 2BY4A 3J7TA 4BBJA 2ZXEA 5AW2A 5A3QA 3KDPA 5AVXA 3BA6A 3AR8A 3AR4A 4J2TA 3NAMA 4RESA 2YFYA 2KIJA 4BEWA 3WGVA 2C88A 4YCLA 2ZBGA 3W5AA 5AVVA 3N5KA 2C8KA 5AVSA
chains in the Genus database with same CATH topology
3AR3A 2EARA 4UU1A 5AW6A 2C9MA 2O9JA 2AGVA 3NANA 4BYGA 5AW1A 3AR2A 3AR6A 3AR7A 4HYTA 4BEVA 3W5DA 3AR5A 2DQSA 4YCMA 5AVZA 4H1WA 5AW4A 4Y3UA 1IWOA 3B8EA 4RETA 3A3YA 5AW9A 3TLMA 5AVYA 5AW8A 5AW7A 2HC8A 4XE5A 5AW0A 3NALA 3FGOA 1SU4A 3W5BA 2ZBDA 1T5SA 2ZBFA 3N8GA 5AVUA 4XOUA 5AVQA 4UU0A 5A3RA 3FPBA 1T5TA 2EAUA 4KYTA 1VFPA 3AR9A 5AVRA 3B9RA 3WGUA 5AVWA 2OA0A 2C8LA 5AVTA 3B9BA 1WPGA 3RFUA 5AW3A 1XP5A 3FPSA 4YCNA 2EATA 2ZBEA 3W5CA 5A3SA 4UMVA 5AW5A 2BY4A 3J7TA 4BBJA 2ZXEA 5AW2A 5A3QA 3KDPA 5AVXA 3BA6A 3AR8A 3AR4A 4J2TA 3NAMA 4RESA 2YFYA 2KIJA 4BEWA 3WGVA 2C88A 4YCLA 2ZBGA 3W5AA 5AVVA 3N5KA 2C8KA 5AVSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RFU A;  4BBJ A;  2KIJ A;  2HC8 A;  4UMV A;  4BEV A;  4BYG A; 
#chains in the Genus database with same CATH topology
 3AR3 A;  2EAR A;  4UU1 A;  5AW6 A;  2C9M A;  2O9J A;  2AGV A;  3NAN A;  4BYG A;  5AW1 A;  3AR2 A;  3AR6 A;  3AR7 A;  4HYT A;  4BEV A;  3W5D A;  3AR5 A;  2DQS A;  4YCM A;  5AVZ A;  4H1W A;  5AW4 A;  4Y3U A;  1IWO A;  3B8E A;  4RET A;  3A3Y A;  5AW9 A;  3TLM A;  5AVY A;  5AW8 A;  5AW7 A;  2HC8 A;  4XE5 A;  5AW0 A;  3NAL A;  3FGO A;  1SU4 A;  3W5B A;  2ZBD A;  1T5S A;  2ZBF A;  3N8G A;  5AVU A;  4XOU A;  5AVQ A;  4UU0 A;  5A3R A;  3FPB A;  1T5T A;  2EAU A;  4KYT A;  1VFP A;  3AR9 A;  5AVR A;  3B9R A;  3WGU A;  5AVW A;  2OA0 A;  2C8L A;  5AVT A;  3B9B A;  1WPG A;  3RFU A;  5AW3 A;  1XP5 A;  3FPS A;  4YCN A;  2EAT A;  2ZBE A;  3W5C A;  5A3S A;  4UMV A;  5AW5 A;  2BY4 A;  3J7T A;  4BBJ A;  2ZXE A;  5AW2 A;  5A3Q A;  3KDP A;  5AVX A;  3BA6 A;  3AR8 A;  3AR4 A;  4J2T A;  3NAM A;  4RES A;  2YFY A;  2KIJ A;  4BEW A;  3WGV A;  2C88 A;  4YCL A;  2ZBG A;  3W5A A;  5AVV A;  3N5K A;  2C8K A;  5AVS A; 
#chains in the Genus database with same CATH homology
 3AR3 A;  2EAR A;  4UU1 A;  5AW6 A;  2C9M A;  2O9J A;  2AGV A;  3NAN A;  4BYG A;  5AW1 A;  3AR2 A;  3AR6 A;  3AR7 A;  4HYT A;  4BEV A;  3W5D A;  3AR5 A;  2DQS A;  4YCM A;  5AVZ A;  4H1W A;  5AW4 A;  4Y3U A;  1IWO A;  3B8E A;  4RET A;  3A3Y A;  5AW9 A;  3TLM A;  5AVY A;  5AW8 A;  5AW7 A;  2HC8 A;  4XE5 A;  5AW0 A;  3NAL A;  3FGO A;  1SU4 A;  3W5B A;  2ZBD A;  1T5S A;  2ZBF A;  3N8G A;  5AVU A;  4XOU A;  5AVQ A;  4UU0 A;  5A3R A;  3FPB A;  1T5T A;  2EAU A;  4KYT A;  1VFP A;  3AR9 A;  5AVR A;  3B9R A;  3WGU A;  5AVW A;  2OA0 A;  2C8L A;  5AVT A;  3B9B A;  1WPG A;  3RFU A;  5AW3 A;  1XP5 A;  3FPS A;  4YCN A;  2EAT A;  2ZBE A;  3W5C A;  5A3S A;  4UMV A;  5AW5 A;  2BY4 A;  3J7T A;  4BBJ A;  2ZXE A;  5AW2 A;  5A3Q A;  3KDP A;  5AVX A;  3BA6 A;  3AR8 A;  3AR4 A;  4J2T A;  3NAM A;  4RES A;  2YFY A;  2KIJ A;  4BEW A;  3WGV A;  2C88 A;  4YCL A;  2ZBG A;  3W5A A;  5AVV A;  3N5K A;  2C8K A;  5AVS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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