2KIJA

Solution structure of the actuator domain of the copper-transporting atpase atp7a
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
119
structure length
119
Chain Sequence
SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 22
structure length 119
sequence length 119
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-05-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.150.20 Mainly Beta Distorted Sandwich Calcium-transporting ATPase, cytoplasmic transduction domain A Calcium-transporting ATPase, cytoplasmic transduction domain A 2kijA00
4UMVA 2HC8A 4BYGA 2KIJA 3RFUA 4BEVA 4BBJA
chains in the Genus database with same CATH superfamily
3BA6A 2EAUA 5AW8A 4KYTA 5AW6A 5AW3A 5AVTA 5AVXA 4UU1A 3N5KA 5AVQA 5AW1A 3W5DA 4BEVA 2EATA 5AW4A 3AR5A 4BEWA 3AR2A 4H1WA 3RFUA 2DQSA 2C9MA 5AW0A 4BYGA 3W5BA 2ZBGA 1WPGA 3WGUA 5AW5A 3B9RA 5AVWA 4RETA 2BY4A 3B8EA 5AVYA 3AR8A 2O9JA 5AVVA 3AR4A 2AGVA 2HC8A 1IWOA 3AR9A 5A3SA 2ZBDA 3NAMA 4UMVA 5AW7A 3B9BA 1T5SA 5A3QA 2C8LA 2ZBFA 4UU0A 2C88A 5A3RA 2C8KA 4BBJA 2ZXEA 5AVSA 3FPSA 1SU4A 3NALA 5AVUA 4J2TA 1XP5A 2OA0A 3N8GA 3NANA 3J7TA 4XE5A 3WGVA 2KIJA 3W5CA 5AVRA 3FPBA 4Y3UA 3A3YA 2EARA 5AW9A 4RESA 2YFYA 3AR7A 1T5TA 3FGOA 2ZBEA 4YCNA 3W5AA 3KDPA 1VFPA 5AVZA 3TLMA 4YCMA 3AR3A 4HYTA 3AR6A 4YCLA 4XOUA 5AW2A
chains in the Genus database with same CATH topology
3BA6A 2EAUA 5AW8A 4KYTA 5AW6A 5AW3A 5AVTA 5AVXA 4UU1A 3N5KA 5AVQA 5AW1A 3W5DA 4BEVA 2EATA 5AW4A 3AR5A 4BEWA 3AR2A 4H1WA 3RFUA 2DQSA 2C9MA 5AW0A 4BYGA 3W5BA 2ZBGA 1WPGA 3WGUA 5AW5A 3B9RA 5AVWA 4RETA 2BY4A 3B8EA 5AVYA 3AR8A 2O9JA 5AVVA 3AR4A 2AGVA 2HC8A 1IWOA 3AR9A 5A3SA 2ZBDA 3NAMA 4UMVA 5AW7A 3B9BA 1T5SA 5A3QA 2C8LA 2ZBFA 4UU0A 2C88A 5A3RA 2C8KA 4BBJA 2ZXEA 5AVSA 3FPSA 1SU4A 3NALA 5AVUA 4J2TA 1XP5A 2OA0A 3N8GA 3NANA 3J7TA 4XE5A 3WGVA 2KIJA 3W5CA 5AVRA 3FPBA 4Y3UA 3A3YA 2EARA 5AW9A 4RESA 2YFYA 3AR7A 1T5TA 3FGOA 2ZBEA 4YCNA 3W5AA 3KDPA 1VFPA 5AVZA 3TLMA 4YCMA 3AR3A 4HYTA 3AR6A 4YCLA 4XOUA 5AW2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UMV A;  2HC8 A;  4BYG A;  2KIJ A;  3RFU A;  4BEV A;  4BBJ A; 
#chains in the Genus database with same CATH topology
 3BA6 A;  2EAU A;  5AW8 A;  4KYT A;  5AW6 A;  5AW3 A;  5AVT A;  5AVX A;  4UU1 A;  3N5K A;  5AVQ A;  5AW1 A;  3W5D A;  4BEV A;  2EAT A;  5AW4 A;  3AR5 A;  4BEW A;  3AR2 A;  4H1W A;  3RFU A;  2DQS A;  2C9M A;  5AW0 A;  4BYG A;  3W5B A;  2ZBG A;  1WPG A;  3WGU A;  5AW5 A;  3B9R A;  5AVW A;  4RET A;  2BY4 A;  3B8E A;  5AVY A;  3AR8 A;  2O9J A;  5AVV A;  3AR4 A;  2AGV A;  2HC8 A;  1IWO A;  3AR9 A;  5A3S A;  2ZBD A;  3NAM A;  4UMV A;  5AW7 A;  3B9B A;  1T5S A;  5A3Q A;  2C8L A;  2ZBF A;  4UU0 A;  2C88 A;  5A3R A;  2C8K A;  4BBJ A;  2ZXE A;  5AVS A;  3FPS A;  1SU4 A;  3NAL A;  5AVU A;  4J2T A;  1XP5 A;  2OA0 A;  3N8G A;  3NAN A;  3J7T A;  4XE5 A;  3WGV A;  2KIJ A;  3W5C A;  5AVR A;  3FPB A;  4Y3U A;  3A3Y A;  2EAR A;  5AW9 A;  4RES A;  2YFY A;  3AR7 A;  1T5T A;  3FGO A;  2ZBE A;  4YCN A;  3W5A A;  3KDP A;  1VFP A;  5AVZ A;  3TLM A;  4YCM A;  3AR3 A;  4HYT A;  3AR6 A;  4YCL A;  4XOU A;  5AW2 A; 
#chains in the Genus database with same CATH homology
 3BA6 A;  2EAU A;  5AW8 A;  4KYT A;  5AW6 A;  5AW3 A;  5AVT A;  5AVX A;  4UU1 A;  3N5K A;  5AVQ A;  5AW1 A;  3W5D A;  4BEV A;  2EAT A;  5AW4 A;  3AR5 A;  4BEW A;  3AR2 A;  4H1W A;  3RFU A;  2DQS A;  2C9M A;  5AW0 A;  4BYG A;  3W5B A;  2ZBG A;  1WPG A;  3WGU A;  5AW5 A;  3B9R A;  5AVW A;  4RET A;  2BY4 A;  3B8E A;  5AVY A;  3AR8 A;  2O9J A;  5AVV A;  3AR4 A;  2AGV A;  2HC8 A;  1IWO A;  3AR9 A;  5A3S A;  2ZBD A;  3NAM A;  4UMV A;  5AW7 A;  3B9B A;  1T5S A;  5A3Q A;  2C8L A;  2ZBF A;  4UU0 A;  2C88 A;  5A3R A;  2C8K A;  4BBJ A;  2ZXE A;  5AVS A;  3FPS A;  1SU4 A;  3NAL A;  5AVU A;  4J2T A;  1XP5 A;  2OA0 A;  3N8G A;  3NAN A;  3J7T A;  4XE5 A;  3WGV A;  2KIJ A;  3W5C A;  5AVR A;  3FPB A;  4Y3U A;  3A3Y A;  2EAR A;  5AW9 A;  4RES A;  2YFY A;  3AR7 A;  1T5T A;  3FGO A;  2ZBE A;  4YCN A;  3W5A A;  3KDP A;  1VFP A;  5AVZ A;  3TLM A;  4YCM A;  3AR3 A;  4HYT A;  3AR6 A;  4YCL A;  4XOU A;  5AW2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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