2L2BA

Structure of stnii-y111n, a mutant of the sea anemone actinoporin sticholysin ii
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
175
structure length
175
Chain Sequence
ALAGTIIAGASLTFQVLDKVLEELGKVSRKIAVGIDNESGGTWTALNAYFRSGTTDVILPEFVPNTKALLYSGRKDTGPVATGAVAAFAYYMSSGNTLGVMFSVPFDYNWNSNWWDVKIYSGKRRADQGMYEDLYYGNPYRGDNGWHEKNLGYGLRMKGIMTSAGEAKMQIKISR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intrinsic local disorder and a network of charge-charge interactions are key to actinoporin membrane disruption and cytotoxicity.
pubmed doi rcsb
molecule tags Toxin
source organism Stichodactyla helianthus
molecule keywords Sticholysin-2
total genus 28
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2010-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 2l2bA00
4Z2QA 4YLDA 4Z2SA 4TSOA 3QDSA 4TSPA 4TSQA 1KD6A 1IAZA 2OFCA 3ZWGA 4TSLA 3LIMA 4TSNA 4WDCA 4TSYA 3VWIA 1O71A 3QDYA 4Z2FA 1O72A 1GWYA 1X99A 2L38A 3QDTA 1Y2WA 3QDUA 2OFEA 3QDWA 2L2BA 1Y2UA 3ZWJA 5BPGA 3QDVA 1Y2XA 3W9PA 1Y2VA 1TZQA 1XI0A 1Y2TA 2KS4A 2OFDA 3QDXA
chains in the Genus database with same CATH superfamily
4Z2QA 4YLDA 4WX5A 4TSOA 4Z2SA 3QDSA 4TSPA 4TSQA 1KD6A 1IAZA 2OFCA 3ZWGA 4WX3A 4TSLA 3LIMA 4TSNA 4P1WB 4TSYA 4WDCA 4JOXA 3VWIA 1O71A 3QDYA 4Z2FA 1O72A 1GWYA 4HPQB 1X99A 2L38A 3QDTA 1Y2WA 3QDUA 2OFEA 3A57A 3QDWA 2L2BA 1Y2UA 3ZWJA 5BPGA 3QDVA 5JHFB 1Y2XA 3W9PA 1Y2VA 4OEBA 1TZQA 1XI0A 1Y2TA 2KS4A 2OFDA 3QDXA
chains in the Genus database with same CATH topology
4Z2QA 4YLDA 4Z2SA 4TSOA 3QDSA 4TSPA 4TSQA 1KD6A 1IAZA 2OFCA 3ZWGA 4TSLA 3LIMA 4TSNA 4WDCA 4TSYA 3VWIA 1O71A 3QDYA 4Z2FA 1O72A 1GWYA 1X99A 2L38A 3QDTA 1Y2WA 3QDUA 2OFEA 3QDWA 2L2BA 1Y2UA 3ZWJA 5BPGA 3QDVA 1Y2XA 3W9PA 1Y2VA 1TZQA 1XI0A 1Y2TA 2KS4A 2OFDA 3QDXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z2Q A;  4YLD A;  4Z2S A;  4TSO A;  3QDS A;  4TSP A;  4TSQ A;  1KD6 A;  1IAZ A;  2OFC A;  3ZWG A;  4TSL A;  3LIM A;  4TSN A;  4WDC A;  4TSY A;  3VWI A;  1O71 A;  3QDY A;  4Z2F A;  1O72 A;  1GWY A;  1X99 A;  2L38 A;  3QDT A;  1Y2W A;  3QDU A;  2OFE A;  3QDW A;  2L2B A;  1Y2U A;  3ZWJ A;  5BPG A;  3QDV A;  1Y2X A;  3W9P A;  1Y2V A;  1TZQ A;  1XI0 A;  1Y2T A;  2KS4 A;  2OFD A;  3QDX A; 
#chains in the Genus database with same CATH topology
 4Z2Q A;  4YLD A;  4WX5 A;  4TSO A;  4Z2S A;  3QDS A;  4TSP A;  4TSQ A;  1KD6 A;  1IAZ A;  2OFC A;  3ZWG A;  4WX3 A;  4TSL A;  3LIM A;  4TSN A;  4P1W B;  4TSY A;  4WDC A;  4JOX A;  3VWI A;  1O71 A;  3QDY A;  4Z2F A;  1O72 A;  1GWY A;  4HPQ B;  1X99 A;  2L38 A;  3QDT A;  1Y2W A;  3QDU A;  2OFE A;  3A57 A;  3QDW A;  2L2B A;  1Y2U A;  3ZWJ A;  5BPG A;  3QDV A;  5JHF B;  1Y2X A;  3W9P A;  1Y2V A;  4OEB A;  1TZQ A;  1XI0 A;  1Y2T A;  2KS4 A;  2OFD A;  3QDX A; 
#chains in the Genus database with same CATH homology
 4Z2Q A;  4YLD A;  4Z2S A;  4TSO A;  3QDS A;  4TSP A;  4TSQ A;  1KD6 A;  1IAZ A;  2OFC A;  3ZWG A;  4TSL A;  3LIM A;  4TSN A;  4WDC A;  4TSY A;  3VWI A;  1O71 A;  3QDY A;  4Z2F A;  1O72 A;  1GWY A;  1X99 A;  2L38 A;  3QDT A;  1Y2W A;  3QDU A;  2OFE A;  3QDW A;  2L2B A;  1Y2U A;  3ZWJ A;  5BPG A;  3QDV A;  1Y2X A;  3W9P A;  1Y2V A;  1TZQ A;  1XI0 A;  1Y2T A;  2KS4 A;  2OFD A;  3QDX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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