5BPGA

Crystal structure of the water-soluble frac purified starting from the trans-membrane pore
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
177
structure length
177
Chain Sequence
DVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Fragaceatoxin C
publication title Bidirectional Transformation of a Metamorphic Protein between the Water-Soluble and Transmembrane Native States
pubmed doi rcsb
source organism Actinia fragacea
total genus 49
structure length 177
sequence length 177
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 5bpgA00
2OFEA 3QDSA 3VWIA 3QDXA 4TSLA 4Z2SA 1Y2VA 1Y2UA 3QDVA 2L38A 1X99A 1O71A 1TZQA 1IAZA 1Y2TA 3LIMA 3QDTA 3QDUA 4YLDA 3W9PA 1GWYA 1Y2WA 1Y2XA 4TSYA 5BPGA 2OFCA 3ZWGA 1O72A 4TSOA 4Z2QA 3QDWA 1KD6A 2L2BA 4TSNA 4WDCA 2OFDA 1XI0A 2KS4A 3QDYA 4TSQA 4Z2FA 3ZWJA 4TSPA
chains in the Genus database with same CATH superfamily
2OFEA 3QDSA 3VWIA 3QDXA 4JOXA 4TSLA 4Z2SA 1Y2VA 1Y2UA 3QDVA 2L38A 1X99A 4WX3A 1O71A 1TZQA 1IAZA 1Y2TA 4WX5A 3LIMA 3QDTA 4HPQB 3QDUA 4YLDA 3W9PA 1GWYA 1Y2WA 1Y2XA 4TSYA 5BPGA 2OFCA 3ZWGA 1O72A 5JHFB 4TSOA 3A57A 4Z2QA 3QDWA 1KD6A 2L2BA 4P1WB 4TSNA 4WDCA 2OFDA 1XI0A 2KS4A 3QDYA 4OEBA 4TSQA 4Z2FA 3ZWJA 4TSPA
chains in the Genus database with same CATH topology
2OFEA 3QDSA 3VWIA 3QDXA 4TSLA 4Z2SA 1Y2VA 1Y2UA 3QDVA 2L38A 1X99A 1O71A 1TZQA 1IAZA 1Y2TA 3LIMA 3QDTA 3QDUA 4YLDA 3W9PA 1GWYA 1Y2WA 1Y2XA 4TSYA 5BPGA 2OFCA 3ZWGA 1O72A 4TSOA 4Z2QA 3QDWA 1KD6A 2L2BA 4TSNA 4WDCA 2OFDA 1XI0A 2KS4A 3QDYA 4TSQA 4Z2FA 3ZWJA 4TSPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OFE A;  3QDS A;  3VWI A;  3QDX A;  4TSL A;  4Z2S A;  1Y2V A;  1Y2U A;  3QDV A;  2L38 A;  1X99 A;  1O71 A;  1TZQ A;  1IAZ A;  1Y2T A;  3LIM A;  3QDT A;  3QDU A;  4YLD A;  3W9P A;  1GWY A;  1Y2W A;  1Y2X A;  4TSY A;  5BPG A;  2OFC A;  3ZWG A;  1O72 A;  4TSO A;  4Z2Q A;  3QDW A;  1KD6 A;  2L2B A;  4TSN A;  4WDC A;  2OFD A;  1XI0 A;  2KS4 A;  3QDY A;  4TSQ A;  4Z2F A;  3ZWJ A;  4TSP A; 
#chains in the Genus database with same CATH topology
 2OFE A;  3QDS A;  3VWI A;  3QDX A;  4JOX A;  4TSL A;  4Z2S A;  1Y2V A;  1Y2U A;  3QDV A;  2L38 A;  1X99 A;  4WX3 A;  1O71 A;  1TZQ A;  1IAZ A;  1Y2T A;  4WX5 A;  3LIM A;  3QDT A;  4HPQ B;  3QDU A;  4YLD A;  3W9P A;  1GWY A;  1Y2W A;  1Y2X A;  4TSY A;  5BPG A;  2OFC A;  3ZWG A;  1O72 A;  5JHF B;  4TSO A;  3A57 A;  4Z2Q A;  3QDW A;  1KD6 A;  2L2B A;  4P1W B;  4TSN A;  4WDC A;  2OFD A;  1XI0 A;  2KS4 A;  3QDY A;  4OEB A;  4TSQ A;  4Z2F A;  3ZWJ A;  4TSP A; 
#chains in the Genus database with same CATH homology
 2OFE A;  3QDS A;  3VWI A;  3QDX A;  4TSL A;  4Z2S A;  1Y2V A;  1Y2U A;  3QDV A;  2L38 A;  1X99 A;  1O71 A;  1TZQ A;  1IAZ A;  1Y2T A;  3LIM A;  3QDT A;  3QDU A;  4YLD A;  3W9P A;  1GWY A;  1Y2W A;  1Y2X A;  4TSY A;  5BPG A;  2OFC A;  3ZWG A;  1O72 A;  4TSO A;  4Z2Q A;  3QDW A;  1KD6 A;  2L2B A;  4TSN A;  4WDC A;  2OFD A;  1XI0 A;  2KS4 A;  3QDY A;  4TSQ A;  4Z2F A;  3ZWJ A;  4TSP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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