2NLLB

Retinoid x receptor-thyroid hormone receptor dna-binding domain heterodimer bound to thyroid response element dna
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
103
structure length
103
Chain Sequence
DELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural determinants of nuclear receptor assembly on DNA direct repeats.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*TP*TP*(5IU)P*CP*AP*GP*GP*TP*
total genus 32
structure length 103
sequence length 103
ec nomenclature
pdb deposition date 1996-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 2nllB00
2HANA 2M9WA 4OORA 4GATA 1LO1A 4OLNA 4HN5A 2FF0A 1R4OA 3E00A 5CBYA 2VUSI 5CBZA 4OV7A 1LATA 3G9MA 5EMPA 3G97A 3DZYD 1YNWA 2NLLB 1HRAA 3G9PA 4NQAB 4CN2C 3G6TA 3DFXA 1R4IA 1LV3A 1A6YA 5CC1A 1R0OB 4TNTA 2GDAA 3G6UA 5GATA 1R4RA 3G6QA 1GNFA 5CBXA 4CN3D 1HCQA 5E6AA 3DZUD 3DZYA 1GDCA 4TMAI 2ENVA 3G6PA 4ONDA 2EBLA 4HC7A 5E6DA 2C7AA 2A66A 1RGDA 1DSZB 7GATA 4HC9A 3G8XA 5CC0A 3GATA 1R0NB 1RXRA 3G9IA 4HCAA 2KAEA 2NLLA 6GATA 4CN3A 5E6CA 3DZUA 1KB2A 3G8UA 2VUTI 1GATA 1R0OA 1HLZA 3M9EA 3DFVC 3G6RA 1HCPA 3G99A 4AA6A 3FYLA 5L0MA 3CBBA 1YNWB 4IQRA 5EMQA 2VUUI 1GLUA 5E6BA 1KB4A 4CN7A 1DSZA 1GA5A 4CN5A 3E00D 3G9JA 2HANB 3VEKC 5KRBB 1R0NA 3VD6C 1KB6A 1CITA 3G9OA 1GAUA 1BY4A 5E69A 5EMCA 4HN6A 2GATA
chains in the Genus database with same CATH superfamily
2HANA 2M9WA 4OORA 4GATA 1LO1A 4OLNA 4HN5A 2FF0A 1R4OA 3E00A 2VUSI 5CBYA 5CBZA 4OV7A 1LATA 3G9MA 5EMPA 3G97A 3DZYD 1YNWA 2NLLB 1HRAA 3G9PA 4NQAB 4CN2C 3G6TA 3DFXA 1R4IA 1LV3A 1A6YA 5CC1A 1R0OB 4TNTA 2GDAA 3G6UA 5GATA 2DS8A 1R4RA 3G6QA 1GNFA 5CBXA 4CN3D 1HCQA 5E6AA 3DZUD 3DZYA 1GDCA 4TMAI 2ENVA 3G6PA 4ONDA 2EBLA 4HC7A 5E6DA 2C7AA 2A66A 1RGDA 1DSZB 7GATA 4HC9A 3G8XA 5CC0A 3GATA 2DS6A 1R0NB 1RXRA 3G9IA 4HCAA 2KAEA 2NLLA 6GATA 4CN3A 5E6CA 3DZUA 1KB2A 3G8UA 2DS5A 2VUTI 1GATA 1R0OA 1HLZA 3M9EA 3DFVC 3G6RA 1HCPA 3G27A 3G99A 4AA6A 3FYLA 5L0MA 3CBBA 1YNWB 4IQRA 5EMQA 2VUUI 1GLUA 5E6BA 1KB4A 4CN7A 1DSZA 1GA5A 4CN5A 3E00D 3G9JA 2HANB 3VEKC 5KRBB 1R0NA 3VD6C 1KB6A 1CITA 3G9OA 1GAUA 1BY4A 5E69A 5EMCA 4HN6A 2GATA
chains in the Genus database with same CATH topology
2HANA 2M9WA 4OORA 4GATA 1LO1A 4OLNA 4HN5A 2FF0A 1R4OA 3E00A 5CBYA 2VUSI 5CBZA 4OV7A 1LATA 3G9MA 5EMPA 3G97A 3DZYD 1YNWA 2NLLB 1HRAA 3G9PA 4NQAB 4CN2C 3G6TA 3DFXA 1R4IA 1LV3A 1A6YA 5CC1A 1R0OB 4TNTA 2GDAA 3G6UA 5GATA 1R4RA 3G6QA 1GNFA 5CBXA 4CN3D 1HCQA 5E6AA 3DZUD 3DZYA 1GDCA 4TMAI 2ENVA 3G6PA 4ONDA 2EBLA 4HC7A 5E6DA 2C7AA 2A66A 1RGDA 1DSZB 7GATA 4HC9A 3G8XA 5CC0A 3GATA 1R0NB 1RXRA 3G9IA 4HCAA 2KAEA 2NLLA 6GATA 4CN3A 5E6CA 3DZUA 1KB2A 3G8UA 2VUTI 1GATA 1R0OA 1HLZA 3M9EA 3DFVC 3G6RA 1HCPA 3G99A 4AA6A 3FYLA 5L0MA 3CBBA 1YNWB 4IQRA 5EMQA 2VUUI 1GLUA 5E6BA 1KB4A 4CN7A 1DSZA 1GA5A 4CN5A 3E00D 3G9JA 2HANB 3VEKC 5KRBB 1R0NA 3VD6C 1KB6A 1CITA 3G9OA 1GAUA 1BY4A 5E69A 5EMCA 4HN6A 2GATA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HAN A;  2M9W A;  4OOR A;  4GAT A;  1LO1 A;  4OLN A;  4HN5 A;  2FF0 A;  1R4O A;  3E00 A;  5CBY A;  2VUS I;  5CBZ A;  4OV7 A;  1LAT A;  3G9M A;  5EMP A;  3G97 A;  3DZY D;  1YNW A;  2NLL B;  1HRA A;  3G9P A;  4NQA B;  4CN2 C;  3G6T A;  3DFX A;  1R4I A;  1LV3 A;  1A6Y A;  5CC1 A;  1R0O B;  4TNT A;  2GDA A;  3G6U A;  5GAT A;  1R4R A;  3G6Q A;  1GNF A;  5CBX A;  4CN3 D;  1HCQ A;  5E6A A;  3DZU D;  3DZY A;  1GDC A;  4TMA I;  2ENV A;  3G6P A;  4OND A;  2EBL A;  4HC7 A;  5E6D A;  2C7A A;  2A66 A;  1RGD A;  1DSZ B;  7GAT A;  4HC9 A;  3G8X A;  5CC0 A;  3GAT A;  1R0N B;  1RXR A;  3G9I A;  4HCA A;  2KAE A;  2NLL A;  6GAT A;  4CN3 A;  5E6C A;  3DZU A;  1KB2 A;  3G8U A;  2VUT I;  1GAT A;  1R0O A;  1HLZ A;  3M9E A;  3DFV C;  3G6R A;  1HCP A;  3G99 A;  4AA6 A;  3FYL A;  5L0M A;  3CBB A;  1YNW B;  4IQR A;  5EMQ A;  2VUU I;  1GLU A;  5E6B A;  1KB4 A;  4CN7 A;  1DSZ A;  1GA5 A;  4CN5 A;  3E00 D;  3G9J A;  2HAN B;  3VEK C;  5KRB B;  1R0N A;  3VD6 C;  1KB6 A;  1CIT A;  3G9O A;  1GAU A;  1BY4 A;  5E69 A;  5EMC A;  4HN6 A;  2GAT A; 
#chains in the Genus database with same CATH topology
 2HAN A;  2M9W A;  4OOR A;  4GAT A;  1LO1 A;  4OLN A;  4HN5 A;  2FF0 A;  1R4O A;  3E00 A;  2VUS I;  5CBY A;  5CBZ A;  4OV7 A;  1LAT A;  3G9M A;  5EMP A;  3G97 A;  3DZY D;  1YNW A;  2NLL B;  1HRA A;  3G9P A;  4NQA B;  4CN2 C;  3G6T A;  3DFX A;  1R4I A;  1LV3 A;  1A6Y A;  5CC1 A;  1R0O B;  4TNT A;  2GDA A;  3G6U A;  5GAT A;  2DS8 A;  1R4R A;  3G6Q A;  1GNF A;  5CBX A;  4CN3 D;  1HCQ A;  5E6A A;  3DZU D;  3DZY A;  1GDC A;  4TMA I;  2ENV A;  3G6P A;  4OND A;  2EBL A;  4HC7 A;  5E6D A;  2C7A A;  2A66 A;  1RGD A;  1DSZ B;  7GAT A;  4HC9 A;  3G8X A;  5CC0 A;  3GAT A;  2DS6 A;  1R0N B;  1RXR A;  3G9I A;  4HCA A;  2KAE A;  2NLL A;  6GAT A;  4CN3 A;  5E6C A;  3DZU A;  1KB2 A;  3G8U A;  2DS5 A;  2VUT I;  1GAT A;  1R0O A;  1HLZ A;  3M9E A;  3DFV C;  3G6R A;  1HCP A;  3G27 A;  3G99 A;  4AA6 A;  3FYL A;  5L0M A;  3CBB A;  1YNW B;  4IQR A;  5EMQ A;  2VUU I;  1GLU A;  5E6B A;  1KB4 A;  4CN7 A;  1DSZ A;  1GA5 A;  4CN5 A;  3E00 D;  3G9J A;  2HAN B;  3VEK C;  5KRB B;  1R0N A;  3VD6 C;  1KB6 A;  1CIT A;  3G9O A;  1GAU A;  1BY4 A;  5E69 A;  5EMC A;  4HN6 A;  2GAT A; 
#chains in the Genus database with same CATH homology
 2HAN A;  2M9W A;  4OOR A;  4GAT A;  1LO1 A;  4OLN A;  4HN5 A;  2FF0 A;  1R4O A;  3E00 A;  5CBY A;  2VUS I;  5CBZ A;  4OV7 A;  1LAT A;  3G9M A;  5EMP A;  3G97 A;  3DZY D;  1YNW A;  2NLL B;  1HRA A;  3G9P A;  4NQA B;  4CN2 C;  3G6T A;  3DFX A;  1R4I A;  1LV3 A;  1A6Y A;  5CC1 A;  1R0O B;  4TNT A;  2GDA A;  3G6U A;  5GAT A;  1R4R A;  3G6Q A;  1GNF A;  5CBX A;  4CN3 D;  1HCQ A;  5E6A A;  3DZU D;  3DZY A;  1GDC A;  4TMA I;  2ENV A;  3G6P A;  4OND A;  2EBL A;  4HC7 A;  5E6D A;  2C7A A;  2A66 A;  1RGD A;  1DSZ B;  7GAT A;  4HC9 A;  3G8X A;  5CC0 A;  3GAT A;  1R0N B;  1RXR A;  3G9I A;  4HCA A;  2KAE A;  2NLL A;  6GAT A;  4CN3 A;  5E6C A;  3DZU A;  1KB2 A;  3G8U A;  2VUT I;  1GAT A;  1R0O A;  1HLZ A;  3M9E A;  3DFV C;  3G6R A;  1HCP A;  3G99 A;  4AA6 A;  3FYL A;  5L0M A;  3CBB A;  1YNW B;  4IQR A;  5EMQ A;  2VUU I;  1GLU A;  5E6B A;  1KB4 A;  4CN7 A;  1DSZ A;  1GA5 A;  4CN5 A;  3E00 D;  3G9J A;  2HAN B;  3VEK C;  5KRB B;  1R0N A;  3VD6 C;  1KB6 A;  1CIT A;  3G9O A;  1GAU A;  1BY4 A;  5E69 A;  5EMC A;  4HN6 A;  2GAT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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