2HHHR

Crystal structure of kasugamycin bound to the 30s ribosomal subunit
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
73
structure length
73
Chain Sequence
PSRKAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSGKEQRILAKTIKRARILGLLPFTEKLVRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 16S ribosomal RNA
total genus 15
structure length 73
sequence length 73
ec nomenclature
pdb deposition date 2006-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF01084 Ribosomal_S18 Ribosomal protein S18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.640.10 Few Secondary Structures Irregular 30s Ribosomal Protein S18 Ribosomal protein S18 2hhhR00
4JI1R 2UUCR 1XNRR 1N34R 1N33R 4JI0R 4DR7R 4YY3R 4JI3R 4X66R 1IBMR 4LFAR 3T1HR 1XMOR 4B3MR 1XMQR 4DR6R 4JI5R 4JI8R 4GKJR 4DR3R 4GKKR 4DR1R 3OTOR 2HHHR 4DV5R 1XNQR 4DV1R 1I94R 2E5LR 4JI2R 4DUZR 4B3RR 4LF7R 4DV0R 2VQFR 4LF4R 4LF5R 1IBLR 4LFCR 4DV4R 1J5ER 3T1YR 1FKAR 5LMNR 1HR0R 2UUBR 4B3TR 1G1XC 4DV2R 2UXCR 4JYAR 4KHPR 4LF8R 4DV6R 4DR2R 4X65R 2F4VR 4JI4R 4LF6R 4NXNR 1N32R 2UXDR 1N36R 4JI7R 4K0KR 4X64R 4JI6R 4NXMR 5LMUR 1HNZR 2UXBR 4DR4R 4B3SR 4DV3R 4DV7R 4LFBR 4LF9R 4JV5R 1IBKR 4AQYR 1FJGR 4DR5R 2UUAR 1HNWR 2ZM6R 4YHHR 2VQER 1HNXR 2UU9R 4X62R 4DUYR 5BR8R 4OX9R
chains in the Genus database with same CATH superfamily
4JI1R 2UUCR 1XNRR 1N34R 1N33R 4JI0R 4DR7R 4YY3R 4JI3R 4X66R 1IBMR 4LFAR 3T1HR 1XMOR 4B3MR 1XMQR 4DR6R 4JI5R 4JI8R 4GKJR 4DR3R 4GKKR 4DR1R 3OTOR 2HHHR 4DV5R 1XNQR 4DV1R 1I94R 2E5LR 4JI2R 4DUZR 4B3RR 4LF7R 4DV0R 2VQFR 4LF4R 4LF5R 1IBLR 4LFCR 4DV4R 1J5ER 3T1YR 1FKAR 5LMNR 1HR0R 2UUBR 4B3TR 1G1XC 4DV2R 2UXCR 4JYAR 4KHPR 4LF8R 4DV6R 4DR2R 4X65R 2F4VR 4JI4R 4LF6R 4NXNR 1N32R 2UXDR 1N36R 4JI7R 4K0KR 4X64R 4JI6R 4NXMR 5LMUR 1HNZR 2UXBR 4DR4R 4B3SR 4DV3R 4DV7R 4LFBR 4LF9R 4JV5R 1IBKR 4AQYR 1FJGR 4DR5R 2UUAR 1HNWR 2ZM6R 4YHHR 2VQER 1HNXR 2UU9R 4X62R 4DUYR 5BR8R 4OX9R
chains in the Genus database with same CATH topology
4JI1R 2UUCR 1XNRR 1N34R 1N33R 4JI0R 4DR7R 4YY3R 4JI3R 4X66R 1IBMR 4LFAR 3T1HR 1XMOR 4B3MR 1XMQR 4DR6R 4JI5R 4JI8R 4GKJR 4DR3R 4GKKR 4DR1R 3OTOR 2HHHR 4DV5R 1XNQR 4DV1R 1I94R 2E5LR 4JI2R 4DUZR 4B3RR 4LF7R 4DV0R 2VQFR 4LF4R 4LF5R 1IBLR 4LFCR 4DV4R 1J5ER 3T1YR 1FKAR 5LMNR 1HR0R 2UUBR 4B3TR 1G1XC 4DV2R 2UXCR 4JYAR 4KHPR 4LF8R 4DV6R 4DR2R 4X65R 2F4VR 4JI4R 4LF6R 4NXNR 1N32R 2UXDR 1N36R 4JI7R 4K0KR 4X64R 4JI6R 4NXMR 5LMUR 1HNZR 2UXBR 4DR4R 4B3SR 4DV3R 4DV7R 4LFBR 4LF9R 4JV5R 1IBKR 4AQYR 1FJGR 4DR5R 2UUAR 1HNWR 2ZM6R 4YHHR 2VQER 1HNXR 2UU9R 4X62R 4DUYR 5BR8R 4OX9R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JI1 R;  2UUC R;  1XNR R;  1N34 R;  1N33 R;  4JI0 R;  4DR7 R;  4YY3 R;  4JI3 R;  4X66 R;  1IBM R;  4LFA R;  3T1H R;  1XMO R;  4B3M R;  1XMQ R;  4DR6 R;  4JI5 R;  4JI8 R;  4GKJ R;  4DR3 R;  4GKK R;  4DR1 R;  3OTO R;  2HHH R;  4DV5 R;  1XNQ R;  4DV1 R;  1I94 R;  2E5L R;  4JI2 R;  4DUZ R;  4B3R R;  4LF7 R;  4DV0 R;  2VQF R;  4LF4 R;  4LF5 R;  1IBL R;  4LFC R;  4DV4 R;  1J5E R;  3T1Y R;  1FKA R;  5LMN R;  1HR0 R;  2UUB R;  4B3T R;  1G1X C;  4DV2 R;  2UXC R;  4JYA R;  4KHP R;  4LF8 R;  4DV6 R;  4DR2 R;  4X65 R;  2F4V R;  4JI4 R;  4LF6 R;  4NXN R;  1N32 R;  2UXD R;  1N36 R;  4JI7 R;  4K0K R;  4X64 R;  4JI6 R;  4NXM R;  5LMU R;  1HNZ R;  2UXB R;  4DR4 R;  4B3S R;  4DV3 R;  4DV7 R;  4LFB R;  4LF9 R;  4JV5 R;  1IBK R;  4AQY R;  1FJG R;  4DR5 R;  2UUA R;  1HNW R;  2ZM6 R;  4YHH R;  2VQE R;  1HNX R;  2UU9 R;  4X62 R;  4DUY R;  5BR8 R;  4OX9 R; 
#chains in the Genus database with same CATH topology
 4JI1 R;  2UUC R;  1XNR R;  1N34 R;  1N33 R;  4JI0 R;  4DR7 R;  4YY3 R;  4JI3 R;  4X66 R;  1IBM R;  4LFA R;  3T1H R;  1XMO R;  4B3M R;  1XMQ R;  4DR6 R;  4JI5 R;  4JI8 R;  4GKJ R;  4DR3 R;  4GKK R;  4DR1 R;  3OTO R;  2HHH R;  4DV5 R;  1XNQ R;  4DV1 R;  1I94 R;  2E5L R;  4JI2 R;  4DUZ R;  4B3R R;  4LF7 R;  4DV0 R;  2VQF R;  4LF4 R;  4LF5 R;  1IBL R;  4LFC R;  4DV4 R;  1J5E R;  3T1Y R;  1FKA R;  5LMN R;  1HR0 R;  2UUB R;  4B3T R;  1G1X C;  4DV2 R;  2UXC R;  4JYA R;  4KHP R;  4LF8 R;  4DV6 R;  4DR2 R;  4X65 R;  2F4V R;  4JI4 R;  4LF6 R;  4NXN R;  1N32 R;  2UXD R;  1N36 R;  4JI7 R;  4K0K R;  4X64 R;  4JI6 R;  4NXM R;  5LMU R;  1HNZ R;  2UXB R;  4DR4 R;  4B3S R;  4DV3 R;  4DV7 R;  4LFB R;  4LF9 R;  4JV5 R;  1IBK R;  4AQY R;  1FJG R;  4DR5 R;  2UUA R;  1HNW R;  2ZM6 R;  4YHH R;  2VQE R;  1HNX R;  2UU9 R;  4X62 R;  4DUY R;  5BR8 R;  4OX9 R; 
#chains in the Genus database with same CATH homology
 4JI1 R;  2UUC R;  1XNR R;  1N34 R;  1N33 R;  4JI0 R;  4DR7 R;  4YY3 R;  4JI3 R;  4X66 R;  1IBM R;  4LFA R;  3T1H R;  1XMO R;  4B3M R;  1XMQ R;  4DR6 R;  4JI5 R;  4JI8 R;  4GKJ R;  4DR3 R;  4GKK R;  4DR1 R;  3OTO R;  2HHH R;  4DV5 R;  1XNQ R;  4DV1 R;  1I94 R;  2E5L R;  4JI2 R;  4DUZ R;  4B3R R;  4LF7 R;  4DV0 R;  2VQF R;  4LF4 R;  4LF5 R;  1IBL R;  4LFC R;  4DV4 R;  1J5E R;  3T1Y R;  1FKA R;  5LMN R;  1HR0 R;  2UUB R;  4B3T R;  1G1X C;  4DV2 R;  2UXC R;  4JYA R;  4KHP R;  4LF8 R;  4DV6 R;  4DR2 R;  4X65 R;  2F4V R;  4JI4 R;  4LF6 R;  4NXN R;  1N32 R;  2UXD R;  1N36 R;  4JI7 R;  4K0K R;  4X64 R;  4JI6 R;  4NXM R;  5LMU R;  1HNZ R;  2UXB R;  4DR4 R;  4B3S R;  4DV3 R;  4DV7 R;  4LFB R;  4LF9 R;  4JV5 R;  1IBK R;  4AQY R;  1FJG R;  4DR5 R;  2UUA R;  1HNW R;  2ZM6 R;  4YHH R;  2VQE R;  1HNX R;  2UU9 R;  4X62 R;  4DUY R;  5BR8 R;  4OX9 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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