3DABA

Structure of the human mdmx protein bound to the p53 tumor suppressor transactivation domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
88
structure length
88
Chain Sequence
IQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
pubmed rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Mdm4 protein
total genus 29
structure length 88
sequence length 88
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2008-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02201 SWIB SWIB/MDM2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.245.10 Mainly Alpha Orthogonal Bundle MDM2 SWIB/MDM2 domain 3dabA00
4J74A 3LNZA 3TPXA 2VYRA 3TJ2A 4JSCA 5HMKA 4JRGA 2N06A 4QO4A 3W69A 3JZSA 3FDOA 4HG7A 4LWVA 2MWYA 4ZYFA 5HMIA 4UD7A 2MPSA 4J7DA 4JVEA 2AXIA 1V31A 1TTVA 3JZPA 3IUXA 4OQ3A 4HBMA 3V3BA 4DIJA 4J7EA 4MDNA 1Z1MA 2LZGA 3FEAA 1YCRA 4LWUA 3LBKA 3EQSA 5LAWA 2N0WA 4JV9A 4J3EA 4IPFA 4JWRA 4ERFA 3EQYA 2GV2A 4OASA 5LAZA 4QOCA 1V32A 3VBGA 1T4FM 3VZVA 2Z5TM 4RXZA 4UE1A 5LAYA 3IWYA 4ODEA 4OBAA 4MDQA 3TU1A 5TRFA 1YCQA 4ZGKA 4LWTA 4OGTA 3U15A 1RV1A 3LBJE 3FE7A 4ZYIA 3G03A 5AFGA 5HMHA 4EREA 2M86B 3DABA 1UHRA 3JZOA 2RUHA 3DACA 3LBLA 1T4EA 4JV7A 4WT2A 4JVRA 4OGNA 4HFZA 3JZRA 2N0UA 4OGVA 4ZYCA 3JZKA 5C5AA 5LAVA 3LNJA 4UMNA 5LN2A 2Z5SM 4OCCA 2N14A 4N5TA 3JZQA 4ZFIA 4ODFA
chains in the Genus database with same CATH superfamily
4J74A 3LNZA 3TPXA 2VYRA 3TJ2A 4JSCA 5HMKA 4JRGA 2N06A 4QO4A 3W69A 3JZSA 3FDOA 4HG7A 4LWVA 2MWYA 4ZYFA 5HMIA 4UD7A 2MPSA 4J7DA 4JVEA 2AXIA 1V31A 1TTVA 3JZPA 3IUXA 4OQ3A 4HBMA 3V3BA 4DIJA 4J7EA 4MDNA 1Z1MA 2LZGA 3FEAA 1YCRA 4LWUA 3LBKA 3EQSA 5LAWA 2N0WA 4JV9A 4J3EA 4IPFA 4JWRA 4ERFA 3EQYA 2GV2A 4OASA 5LAZA 4QOCA 1V32A 3VBGA 1T4FM 3VZVA 2Z5TM 4RXZA 4UE1A 5LAYA 3IWYA 4ODEA 4OBAA 4MDQA 3TU1A 5TRFA 1YCQA 4ZGKA 4LWTA 4OGTA 3U15A 1RV1A 3LBJE 3FE7A 4ZYIA 3G03A 5AFGA 5HMHA 4EREA 2M86B 3DABA 1UHRA 3JZOA 2RUHA 3DACA 3LBLA 1T4EA 4JV7A 4WT2A 4JVRA 4OGNA 4HFZA 3JZRA 2N0UA 4OGVA 4ZYCA 3JZKA 5C5AA 5LAVA 3LNJA 4UMNA 5LN2A 2Z5SM 4OCCA 2N14A 4N5TA 3JZQA 4ZFIA 4ODFA
chains in the Genus database with same CATH topology
4J74A 3LNZA 3TPXA 2VYRA 3TJ2A 4JSCA 5HMKA 4JRGA 2N06A 4QO4A 3W69A 3JZSA 3FDOA 4HG7A 4LWVA 2MWYA 4ZYFA 5HMIA 4UD7A 2MPSA 4J7DA 4JVEA 2AXIA 1V31A 1TTVA 3JZPA 3IUXA 4OQ3A 4HBMA 3V3BA 4DIJA 4J7EA 4MDNA 1Z1MA 2LZGA 3FEAA 1YCRA 4LWUA 3LBKA 3EQSA 5LAWA 2N0WA 4JV9A 4J3EA 4IPFA 4JWRA 4ERFA 3EQYA 2GV2A 4OASA 5LAZA 4QOCA 1V32A 3VBGA 1T4FM 3VZVA 2Z5TM 4RXZA 4UE1A 5LAYA 3IWYA 4ODEA 4OBAA 4MDQA 3TU1A 5TRFA 1YCQA 4ZGKA 4LWTA 4OGTA 3U15A 1RV1A 3LBJE 3FE7A 4ZYIA 3G03A 5AFGA 5HMHA 4EREA 2M86B 3DABA 1UHRA 3JZOA 2RUHA 3DACA 3LBLA 1T4EA 4JV7A 4WT2A 4JVRA 4OGNA 4HFZA 3JZRA 2N0UA 4OGVA 4ZYCA 3JZKA 5C5AA 5LAVA 3LNJA 4UMNA 5LN2A 2Z5SM 4OCCA 2N14A 4N5TA 3JZQA 4ZFIA 4ODFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J74 A;  3LNZ A;  3TPX A;  2VYR A;  3TJ2 A;  4JSC A;  5HMK A;  4JRG A;  2N06 A;  4QO4 A;  3W69 A;  3JZS A;  3FDO A;  4HG7 A;  4LWV A;  2MWY A;  4ZYF A;  5HMI A;  4UD7 A;  2MPS A;  4J7D A;  4JVE A;  2AXI A;  1V31 A;  1TTV A;  3JZP A;  3IUX A;  4OQ3 A;  4HBM A;  3V3B A;  4DIJ A;  4J7E A;  4MDN A;  1Z1M A;  2LZG A;  3FEA A;  1YCR A;  4LWU A;  3LBK A;  3EQS A;  5LAW A;  2N0W A;  4JV9 A;  4J3E A;  4IPF A;  4JWR A;  4ERF A;  3EQY A;  2GV2 A;  4OAS A;  5LAZ A;  4QOC A;  1V32 A;  3VBG A;  1T4F M;  3VZV A;  2Z5T M;  4RXZ A;  4UE1 A;  5LAY A;  3IWY A;  4ODE A;  4OBA A;  4MDQ A;  3TU1 A;  5TRF A;  1YCQ A;  4ZGK A;  4LWT A;  4OGT A;  3U15 A;  1RV1 A;  3LBJ E;  3FE7 A;  4ZYI A;  3G03 A;  5AFG A;  5HMH A;  4ERE A;  2M86 B;  3DAB A;  1UHR A;  3JZO A;  2RUH A;  3DAC A;  3LBL A;  1T4E A;  4JV7 A;  4WT2 A;  4JVR A;  4OGN A;  4HFZ A;  3JZR A;  2N0U A;  4OGV A;  4ZYC A;  3JZK A;  5C5A A;  5LAV A;  3LNJ A;  4UMN A;  5LN2 A;  2Z5S M;  4OCC A;  2N14 A;  4N5T A;  3JZQ A;  4ZFI A;  4ODF A; 
#chains in the Genus database with same CATH topology
 4J74 A;  3LNZ A;  3TPX A;  2VYR A;  3TJ2 A;  4JSC A;  5HMK A;  4JRG A;  2N06 A;  4QO4 A;  3W69 A;  3JZS A;  3FDO A;  4HG7 A;  4LWV A;  2MWY A;  4ZYF A;  5HMI A;  4UD7 A;  2MPS A;  4J7D A;  4JVE A;  2AXI A;  1V31 A;  1TTV A;  3JZP A;  3IUX A;  4OQ3 A;  4HBM A;  3V3B A;  4DIJ A;  4J7E A;  4MDN A;  1Z1M A;  2LZG A;  3FEA A;  1YCR A;  4LWU A;  3LBK A;  3EQS A;  5LAW A;  2N0W A;  4JV9 A;  4J3E A;  4IPF A;  4JWR A;  4ERF A;  3EQY A;  2GV2 A;  4OAS A;  5LAZ A;  4QOC A;  1V32 A;  3VBG A;  1T4F M;  3VZV A;  2Z5T M;  4RXZ A;  4UE1 A;  5LAY A;  3IWY A;  4ODE A;  4OBA A;  4MDQ A;  3TU1 A;  5TRF A;  1YCQ A;  4ZGK A;  4LWT A;  4OGT A;  3U15 A;  1RV1 A;  3LBJ E;  3FE7 A;  4ZYI A;  3G03 A;  5AFG A;  5HMH A;  4ERE A;  2M86 B;  3DAB A;  1UHR A;  3JZO A;  2RUH A;  3DAC A;  3LBL A;  1T4E A;  4JV7 A;  4WT2 A;  4JVR A;  4OGN A;  4HFZ A;  3JZR A;  2N0U A;  4OGV A;  4ZYC A;  3JZK A;  5C5A A;  5LAV A;  3LNJ A;  4UMN A;  5LN2 A;  2Z5S M;  4OCC A;  2N14 A;  4N5T A;  3JZQ A;  4ZFI A;  4ODF A; 
#chains in the Genus database with same CATH homology
 4J74 A;  3LNZ A;  3TPX A;  2VYR A;  3TJ2 A;  4JSC A;  5HMK A;  4JRG A;  2N06 A;  4QO4 A;  3W69 A;  3JZS A;  3FDO A;  4HG7 A;  4LWV A;  2MWY A;  4ZYF A;  5HMI A;  4UD7 A;  2MPS A;  4J7D A;  4JVE A;  2AXI A;  1V31 A;  1TTV A;  3JZP A;  3IUX A;  4OQ3 A;  4HBM A;  3V3B A;  4DIJ A;  4J7E A;  4MDN A;  1Z1M A;  2LZG A;  3FEA A;  1YCR A;  4LWU A;  3LBK A;  3EQS A;  5LAW A;  2N0W A;  4JV9 A;  4J3E A;  4IPF A;  4JWR A;  4ERF A;  3EQY A;  2GV2 A;  4OAS A;  5LAZ A;  4QOC A;  1V32 A;  3VBG A;  1T4F M;  3VZV A;  2Z5T M;  4RXZ A;  4UE1 A;  5LAY A;  3IWY A;  4ODE A;  4OBA A;  4MDQ A;  3TU1 A;  5TRF A;  1YCQ A;  4ZGK A;  4LWT A;  4OGT A;  3U15 A;  1RV1 A;  3LBJ E;  3FE7 A;  4ZYI A;  3G03 A;  5AFG A;  5HMH A;  4ERE A;  2M86 B;  3DAB A;  1UHR A;  3JZO A;  2RUH A;  3DAC A;  3LBL A;  1T4E A;  4JV7 A;  4WT2 A;  4JVR A;  4OGN A;  4HFZ A;  3JZR A;  2N0U A;  4OGV A;  4ZYC A;  3JZK A;  5C5A A;  5LAV A;  3LNJ A;  4UMN A;  5LN2 A;  2Z5S M;  4OCC A;  2N14 A;  4N5T A;  3JZQ A;  4ZFI A;  4ODF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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