3FDOA

Structure of human mdmx in complex with high affinity peptide
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
90
structure length
90
Chain Sequence
IQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx
pubmed rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Protein Mdm4
total genus 27
structure length 90
sequence length 90
ec nomenclature
pdb deposition date 2008-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02201 SWIB SWIB/MDM2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.245.10 Mainly Alpha Orthogonal Bundle MDM2 SWIB/MDM2 domain 3fdoA00
4ZYFA 5LAWA 3EQYA 3FEAA 4JVRA 2Z5TM 4OGVA 3JZOA 5HMKA 3VBGA 4JSCA 4WT2A 2N0UA 4MDNA 4JWRA 4JRGA 4OCCA 3FDOA 4EREA 5AFGA 3G03A 4J7DA 1UHRA 2GV2A 1T4EA 4OASA 3LNJA 4QOCA 3W69A 4OQ3A 3JZPA 4ZFIA 2MWYA 4OGTA 2N06A 5C5AA 4J7EA 3V3BA 3EQSA 4RXZA 3DACA 3FE7A 2AXIA 5LAVA 4J3EA 3IUXA 3DABA 4ODFA 3JZKA 4N5TA 5TRFA 2N0WA 1YCRA 2LZGA 2Z5SM 4JVEA 4LWUA 4UE1A 5HMIA 2RUHA 4ERFA 3LNZA 5LAZA 2M86B 4LWTA 3TU1A 3IWYA 3LBKA 3LBJE 4JV7A 4J74A 1Z1MA 4IPFA 1T4FM 4QO4A 4ZGKA 4LWVA 4ZYIA 4OGNA 3LBLA 4JV9A 1RV1A 4ZYCA 3VZVA 4UMNA 4HG7A 4UD7A 3U15A 2VYRA 3JZRA 4HFZA 3TPXA 1TTVA 2N14A 5HMHA 2MPSA 5LN2A 1V31A 4DIJA 1YCQA 3JZSA 4OBAA 4HBMA 4MDQA 1V32A 3TJ2A 5LAYA 4ODEA 3JZQA
chains in the Genus database with same CATH superfamily
4ZYFA 5LAWA 3EQYA 3FEAA 4JVRA 2Z5TM 4OGVA 3JZOA 5HMKA 3VBGA 4JSCA 4WT2A 2N0UA 4MDNA 4JWRA 4JRGA 4OCCA 3FDOA 4EREA 5AFGA 3G03A 4J7DA 1UHRA 2GV2A 1T4EA 4OASA 3LNJA 4QOCA 3W69A 4OQ3A 3JZPA 4ZFIA 2MWYA 4OGTA 2N06A 5C5AA 4J7EA 3V3BA 3EQSA 4RXZA 3DACA 3FE7A 2AXIA 5LAVA 4J3EA 3IUXA 3DABA 4ODFA 3JZKA 4N5TA 5TRFA 2N0WA 1YCRA 2LZGA 2Z5SM 4JVEA 4LWUA 4UE1A 5HMIA 2RUHA 4ERFA 3LNZA 5LAZA 2M86B 4LWTA 3TU1A 3IWYA 3LBKA 3LBJE 4JV7A 4J74A 1Z1MA 4IPFA 1T4FM 4QO4A 4ZGKA 4LWVA 4ZYIA 4OGNA 3LBLA 4JV9A 1RV1A 4ZYCA 3VZVA 4UMNA 4HG7A 4UD7A 3U15A 2VYRA 3JZRA 4HFZA 3TPXA 1TTVA 2N14A 5HMHA 2MPSA 5LN2A 1V31A 4DIJA 1YCQA 3JZSA 4OBAA 4HBMA 4MDQA 1V32A 3TJ2A 5LAYA 4ODEA 3JZQA
chains in the Genus database with same CATH topology
4ZYFA 5LAWA 3EQYA 3FEAA 4JVRA 2Z5TM 4OGVA 3JZOA 5HMKA 3VBGA 4JSCA 4WT2A 2N0UA 4MDNA 4JWRA 4JRGA 4OCCA 3FDOA 4EREA 5AFGA 3G03A 4J7DA 1UHRA 2GV2A 1T4EA 4OASA 3LNJA 4QOCA 3W69A 4OQ3A 3JZPA 4ZFIA 2MWYA 4OGTA 2N06A 5C5AA 4J7EA 3V3BA 3EQSA 4RXZA 3DACA 3FE7A 2AXIA 5LAVA 4J3EA 3IUXA 3DABA 4ODFA 3JZKA 4N5TA 5TRFA 2N0WA 1YCRA 2LZGA 2Z5SM 4JVEA 4LWUA 4UE1A 5HMIA 2RUHA 4ERFA 3LNZA 5LAZA 2M86B 4LWTA 3TU1A 3IWYA 3LBKA 3LBJE 4JV7A 4J74A 1Z1MA 4IPFA 1T4FM 4QO4A 4ZGKA 4LWVA 4ZYIA 4OGNA 3LBLA 4JV9A 1RV1A 4ZYCA 3VZVA 4UMNA 4HG7A 4UD7A 3U15A 2VYRA 3JZRA 4HFZA 3TPXA 1TTVA 2N14A 5HMHA 2MPSA 5LN2A 1V31A 4DIJA 1YCQA 3JZSA 4OBAA 4HBMA 4MDQA 1V32A 3TJ2A 5LAYA 4ODEA 3JZQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZYF A;  5LAW A;  3EQY A;  3FEA A;  4JVR A;  2Z5T M;  4OGV A;  3JZO A;  5HMK A;  3VBG A;  4JSC A;  4WT2 A;  2N0U A;  4MDN A;  4JWR A;  4JRG A;  4OCC A;  3FDO A;  4ERE A;  5AFG A;  3G03 A;  4J7D A;  1UHR A;  2GV2 A;  1T4E A;  4OAS A;  3LNJ A;  4QOC A;  3W69 A;  4OQ3 A;  3JZP A;  4ZFI A;  2MWY A;  4OGT A;  2N06 A;  5C5A A;  4J7E A;  3V3B A;  3EQS A;  4RXZ A;  3DAC A;  3FE7 A;  2AXI A;  5LAV A;  4J3E A;  3IUX A;  3DAB A;  4ODF A;  3JZK A;  4N5T A;  5TRF A;  2N0W A;  1YCR A;  2LZG A;  2Z5S M;  4JVE A;  4LWU A;  4UE1 A;  5HMI A;  2RUH A;  4ERF A;  3LNZ A;  5LAZ A;  2M86 B;  4LWT A;  3TU1 A;  3IWY A;  3LBK A;  3LBJ E;  4JV7 A;  4J74 A;  1Z1M A;  4IPF A;  1T4F M;  4QO4 A;  4ZGK A;  4LWV A;  4ZYI A;  4OGN A;  3LBL A;  4JV9 A;  1RV1 A;  4ZYC A;  3VZV A;  4UMN A;  4HG7 A;  4UD7 A;  3U15 A;  2VYR A;  3JZR A;  4HFZ A;  3TPX A;  1TTV A;  2N14 A;  5HMH A;  2MPS A;  5LN2 A;  1V31 A;  4DIJ A;  1YCQ A;  3JZS A;  4OBA A;  4HBM A;  4MDQ A;  1V32 A;  3TJ2 A;  5LAY A;  4ODE A;  3JZQ A; 
#chains in the Genus database with same CATH topology
 4ZYF A;  5LAW A;  3EQY A;  3FEA A;  4JVR A;  2Z5T M;  4OGV A;  3JZO A;  5HMK A;  3VBG A;  4JSC A;  4WT2 A;  2N0U A;  4MDN A;  4JWR A;  4JRG A;  4OCC A;  3FDO A;  4ERE A;  5AFG A;  3G03 A;  4J7D A;  1UHR A;  2GV2 A;  1T4E A;  4OAS A;  3LNJ A;  4QOC A;  3W69 A;  4OQ3 A;  3JZP A;  4ZFI A;  2MWY A;  4OGT A;  2N06 A;  5C5A A;  4J7E A;  3V3B A;  3EQS A;  4RXZ A;  3DAC A;  3FE7 A;  2AXI A;  5LAV A;  4J3E A;  3IUX A;  3DAB A;  4ODF A;  3JZK A;  4N5T A;  5TRF A;  2N0W A;  1YCR A;  2LZG A;  2Z5S M;  4JVE A;  4LWU A;  4UE1 A;  5HMI A;  2RUH A;  4ERF A;  3LNZ A;  5LAZ A;  2M86 B;  4LWT A;  3TU1 A;  3IWY A;  3LBK A;  3LBJ E;  4JV7 A;  4J74 A;  1Z1M A;  4IPF A;  1T4F M;  4QO4 A;  4ZGK A;  4LWV A;  4ZYI A;  4OGN A;  3LBL A;  4JV9 A;  1RV1 A;  4ZYC A;  3VZV A;  4UMN A;  4HG7 A;  4UD7 A;  3U15 A;  2VYR A;  3JZR A;  4HFZ A;  3TPX A;  1TTV A;  2N14 A;  5HMH A;  2MPS A;  5LN2 A;  1V31 A;  4DIJ A;  1YCQ A;  3JZS A;  4OBA A;  4HBM A;  4MDQ A;  1V32 A;  3TJ2 A;  5LAY A;  4ODE A;  3JZQ A; 
#chains in the Genus database with same CATH homology
 4ZYF A;  5LAW A;  3EQY A;  3FEA A;  4JVR A;  2Z5T M;  4OGV A;  3JZO A;  5HMK A;  3VBG A;  4JSC A;  4WT2 A;  2N0U A;  4MDN A;  4JWR A;  4JRG A;  4OCC A;  3FDO A;  4ERE A;  5AFG A;  3G03 A;  4J7D A;  1UHR A;  2GV2 A;  1T4E A;  4OAS A;  3LNJ A;  4QOC A;  3W69 A;  4OQ3 A;  3JZP A;  4ZFI A;  2MWY A;  4OGT A;  2N06 A;  5C5A A;  4J7E A;  3V3B A;  3EQS A;  4RXZ A;  3DAC A;  3FE7 A;  2AXI A;  5LAV A;  4J3E A;  3IUX A;  3DAB A;  4ODF A;  3JZK A;  4N5T A;  5TRF A;  2N0W A;  1YCR A;  2LZG A;  2Z5S M;  4JVE A;  4LWU A;  4UE1 A;  5HMI A;  2RUH A;  4ERF A;  3LNZ A;  5LAZ A;  2M86 B;  4LWT A;  3TU1 A;  3IWY A;  3LBK A;  3LBJ E;  4JV7 A;  4J74 A;  1Z1M A;  4IPF A;  1T4F M;  4QO4 A;  4ZGK A;  4LWV A;  4ZYI A;  4OGN A;  3LBL A;  4JV9 A;  1RV1 A;  4ZYC A;  3VZV A;  4UMN A;  4HG7 A;  4UD7 A;  3U15 A;  2VYR A;  3JZR A;  4HFZ A;  3TPX A;  1TTV A;  2N14 A;  5HMH A;  2MPS A;  5LN2 A;  1V31 A;  4DIJ A;  1YCQ A;  3JZS A;  4OBA A;  4HBM A;  4MDQ A;  1V32 A;  3TJ2 A;  5LAY A;  4ODE A;  3JZQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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