The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
36
|
sequence length |
117
|
structure length |
117
|
Chain Sequence |
PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFALEH
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site.
pubmed doi rcsb |
| molecule tags |
Isomerase
|
| source organism |
Homo sapiens
|
| molecule keywords |
Macrophage migration inhibitory factor
|
| total genus |
36
|
| structure length |
117
|
| sequence length |
117
|
| chains with identical sequence |
B, C
|
| ec nomenclature |
ec
5.3.2.1: Phenylpyruvate tautomerase. |
| pdb deposition date | 2009-12-22 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01187 | MIF | Macrophage migration inhibitory factor (MIF) |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Macrophage Migration Inhibitory Factor | Macrophage Migration Inhibitory Factor |
#chains in the Genus database with same CATH superfamily 2OOW A; 1GCZ A; 3T5S A; 4GRQ A; 4TRU A; 4Z1T A; 2GDG A; 3RF5 A; 4F2K A; 3M21 A; 3FWU A; 4GRR A; 1P1G A; 3MJZ A; 3ABF A; 4OTC A; 1BJP A; 3WNS A; 2OS5 A; 5BSJ A; 1MFI A; 3SMC A; 5J7Q A; 2OOZ A; 3JSG A; 4P01 A; 4XX7 A; 3N4G A; 3MB2 A; 3SMB A; 4WR8 A; 1LJT A; 1GYX A; 2AAJ A; 3L5T A; 3M20 A; 3RY0 A; 4GRU A; 4OYQ A; 5B4O A; 3CE4 A; 3EJ7 B; 4U5P A; 2FM7 A; 2WKB A; 4FAZ A; 3U18 A; 3GAC A; 2OPA A; 5BSI A; 2AAL A; 1OTG A; 4JJ9 A; 2WKF A; 2OP8 A; 4LHO A; 5EIZ A; 4P7S A; 3WNT A; 1GYY A; 3JTU A; 2FLZ A; 2XCZ A; 3N4H A; 2FLT A; 4FDX A; 4OSF A; 4GRO A; 4WRB A; 1S0Y A; 1U9D A; 3MLC A; 3L5U A; 4GRN A; 4NWQ B; 3N4D A; 1DPT A; 3IJJ A; 3EJ3 A; 3EJ7 A; 2OOH A; 4X19 A; 5BS9 A; 3B64 A; 1MIF A; 2X4K A; 5J7P A; 4P7M A; 4Z1U A; 1CGQ A; 5CLN A; 1FIM A; 3EJ9 B; 4OTB A; 1OTF A; 1HFO A; 4XX8 A; 3KER A; 4X1C C; 3MB2 B; 3DJI A; 5BSC A; 4EVG A; 4GUM A; 3IJG A; 3L5V A; 3MF8 A; 4DH4 A; 4P0H A; 3FWT A; 3WNR A; 4PKZ A; 3L5S A; 1GIF A; 4OTA A; 4PKK A; 5HVS A; 4PLU A; 3MF7 A; 4Q3F A; 4Z15 A; 3HOF A; 3E6Q A; 2WKF B; 3KAN A; 4GRP A; 3RF4 A; 1UIZ A; 2ORM A; 4JCU A; 1GD0 A; 4ETG A; 3B9S A; 4U5R A; 3DJH A; 2AAG A; 3EJ9 A; 3GAD A; 1S0Y B; 4LHP A; 1MWW A; 3L5P A; 3C6V A; 4EUI A; 4X1C A; 4LKB A; 5CLO A; 4K9G A; 1MFF A; 3EJ3 B; 4M1A A; 4TRF A; 1CA7 A; 3L5R A; 1GYJ A; 4NWP E; 5HVV A; 3JSF A; 5HVT A; #chains in the Genus database with same CATH topology 2OOW A; 1GCZ A; 3T5S A; 4GRQ A; 4TRU A; 4Z1T A; 2GDG A; 3RF5 A; 4F2K A; 3M21 A; 3FWU A; 4GRR A; 1P1G A; 3MJZ A; 3ABF A; 4OTC A; 1BJP A; 3WNS A; 2OS5 A; 5BSJ A; 1MFI A; 3SMC A; 5J7Q A; 2OOZ A; 3JSG A; 4P01 A; 4XX7 A; 3N4G A; 3MB2 A; 3SMB A; 4WR8 A; 1LJT A; 1GYX A; 2AAJ A; 3L5T A; 3M20 A; 3RY0 A; 4GRU A; 4OYQ A; 5B4O A; 3CE4 A; 3EJ7 B; 4U5P A; 2FM7 A; 2WKB A; 4FAZ A; 3U18 A; 3GAC A; 2OPA A; 5BSI A; 2AAL A; 1OTG A; 4JJ9 A; 2WKF A; 2OP8 A; 4LHO A; 5EIZ A; 4P7S A; 3WNT A; 1GYY A; 3JTU A; 2FLZ A; 2XCZ A; 3N4H A; 2FLT A; 4FDX A; 4OSF A; 4GRO A; 4WRB A; 1S0Y A; 1U9D A; 3MLC A; 3L5U A; 4GRN A; 4NWQ B; 3N4D A; 1DPT A; 3IJJ A; 3EJ3 A; 3EJ7 A; 2OOH A; 4X19 A; 5BS9 A; 3B64 A; 1MIF A; 2X4K A; 5J7P A; 4P7M A; 4Z1U A; 1CGQ A; 5CLN A; 1FIM A; 3EJ9 B; 4OTB A; 1OTF A; 1HFO A; 4XX8 A; 3KER A; 4X1C C; 3MB2 B; 3DJI A; 5BSC A; 4EVG A; 4GUM A; 3IJG A; 3L5V A; 3MF8 A; 4DH4 A; 4P0H A; 3FWT A; 3WNR A; 4PKZ A; 3L5S A; 1GIF A; 4OTA A; 4PKK A; 5HVS A; 4PLU A; 3MF7 A; 4Q3F A; 4Z15 A; 3HOF A; 3E6Q A; 2WKF B; 3KAN A; 4GRP A; 3RF4 A; 1UIZ A; 2ORM A; 4JCU A; 1GD0 A; 4ETG A; 3B9S A; 4U5R A; 3DJH A; 2AAG A; 3EJ9 A; 3GAD A; 1S0Y B; 4LHP A; 1MWW A; 3L5P A; 3C6V A; 4EUI A; 4X1C A; 4LKB A; 5CLO A; 4K9G A; 1MFF A; 3EJ3 B; 4M1A A; 4TRF A; 1CA7 A; 3L5R A; 1GYJ A; 4NWP E; 5HVV A; 3JSF A; 5HVT A; #chains in the Genus database with same CATH homology 2OOW A; 1GCZ A; 3T5S A; 4GRQ A; 4TRU A; 4Z1T A; 2GDG A; 3RF5 A; 4F2K A; 3M21 A; 3FWU A; 4GRR A; 1P1G A; 3MJZ A; 3ABF A; 4OTC A; 1BJP A; 3WNS A; 2OS5 A; 5BSJ A; 1MFI A; 3SMC A; 5J7Q A; 2OOZ A; 3JSG A; 4P01 A; 4XX7 A; 3N4G A; 3MB2 A; 3SMB A; 4WR8 A; 1LJT A; 1GYX A; 2AAJ A; 3L5T A; 3M20 A; 3RY0 A; 4GRU A; 4OYQ A; 5B4O A; 3CE4 A; 3EJ7 B; 4U5P A; 2FM7 A; 2WKB A; 4FAZ A; 3U18 A; 3GAC A; 2OPA A; 5BSI A; 2AAL A; 1OTG A; 4JJ9 A; 2WKF A; 2OP8 A; 4LHO A; 5EIZ A; 4P7S A; 3WNT A; 1GYY A; 3JTU A; 2FLZ A; 2XCZ A; 3N4H A; 2FLT A; 4FDX A; 4OSF A; 4GRO A; 4WRB A; 1S0Y A; 1U9D A; 3MLC A; 3L5U A; 4GRN A; 4NWQ B; 3N4D A; 1DPT A; 3IJJ A; 3EJ3 A; 3EJ7 A; 2OOH A; 4X19 A; 5BS9 A; 3B64 A; 1MIF A; 2X4K A; 5J7P A; 4P7M A; 4Z1U A; 1CGQ A; 5CLN A; 1FIM A; 3EJ9 B; 4OTB A; 1OTF A; 1HFO A; 4XX8 A; 3KER A; 4X1C C; 3MB2 B; 3DJI A; 5BSC A; 4EVG A; 4GUM A; 3IJG A; 3L5V A; 3MF8 A; 4DH4 A; 4P0H A; 3FWT A; 3WNR A; 4PKZ A; 3L5S A; 1GIF A; 4OTA A; 4PKK A; 5HVS A; 4PLU A; 3MF7 A; 4Q3F A; 4Z15 A; 3HOF A; 3E6Q A; 2WKF B; 3KAN A; 4GRP A; 3RF4 A; 1UIZ A; 2ORM A; 4JCU A; 1GD0 A; 4ETG A; 3B9S A; 4U5R A; 3DJH A; 2AAG A; 3EJ9 A; 3GAD A; 1S0Y B; 4LHP A; 1MWW A; 3L5P A; 3C6V A; 4EUI A; 4X1C A; 4LKB A; 5CLO A; 4K9G A; 1MFF A; 3EJ3 B; 4M1A A; 4TRF A; 1CA7 A; 3L5R A; 1GYJ A; 4NWP E; 5HVV A; 3JSF A; 5HVT A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
