3LIMA

Crystal structure of the pore forming toxin frac from sea anemone actinia fragacea
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
178
structure length
178
Chain Sequence
ADVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the oligomerization and architecture of eukaryotic membrane pore-forming toxins.
pubmed doi rcsb
molecule tags Toxin
molecule keywords Fragaceatoxin C
total genus 50
structure length 178
sequence length 178
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2010-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 3limA00
3ZWJA 1Y2TA 3LIMA 3W9PA 2OFEA 2KS4A 3QDUA 3QDWA 4TSYA 3ZWGA 5BPGA 1Y2XA 4WDCA 4TSNA 2OFDA 2L38A 4Z2SA 1TZQA 3QDYA 3VWIA 1X99A 1XI0A 4TSQA 1Y2UA 3QDXA 3QDVA 4TSLA 1IAZA 1O72A 1O71A 1KD6A 2L2BA 4YLDA 1GWYA 4TSPA 1Y2VA 1Y2WA 3QDSA 3QDTA 4Z2FA 4Z2QA 4TSOA 2OFCA
chains in the Genus database with same CATH superfamily
3ZWJA 4HPQB 1Y2TA 3LIMA 3W9PA 2OFEA 2KS4A 3QDUA 3QDWA 4TSYA 3ZWGA 5BPGA 1Y2XA 4WDCA 4TSNA 2OFDA 2L38A 3A57A 4Z2SA 1TZQA 3QDYA 3VWIA 1X99A 1XI0A 4TSQA 4WX5A 1Y2UA 3QDXA 3QDVA 4TSLA 1IAZA 1O72A 1O71A 1KD6A 2L2BA 4YLDA 1GWYA 4OEBA 4TSPA 1Y2VA 1Y2WA 5JHFB 3QDSA 4P1WB 3QDTA 4Z2FA 4Z2QA 4TSOA 2OFCA 4WX3A 4JOXA
chains in the Genus database with same CATH topology
3ZWJA 1Y2TA 3LIMA 3W9PA 2OFEA 2KS4A 3QDUA 3QDWA 4TSYA 3ZWGA 5BPGA 1Y2XA 4WDCA 4TSNA 2OFDA 2L38A 4Z2SA 1TZQA 3QDYA 3VWIA 1X99A 1XI0A 4TSQA 1Y2UA 3QDXA 3QDVA 4TSLA 1IAZA 1O72A 1O71A 1KD6A 2L2BA 4YLDA 1GWYA 4TSPA 1Y2VA 1Y2WA 3QDSA 3QDTA 4Z2FA 4Z2QA 4TSOA 2OFCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZWJ A;  1Y2T A;  3LIM A;  3W9P A;  2OFE A;  2KS4 A;  3QDU A;  3QDW A;  4TSY A;  3ZWG A;  5BPG A;  1Y2X A;  4WDC A;  4TSN A;  2OFD A;  2L38 A;  4Z2S A;  1TZQ A;  3QDY A;  3VWI A;  1X99 A;  1XI0 A;  4TSQ A;  1Y2U A;  3QDX A;  3QDV A;  4TSL A;  1IAZ A;  1O72 A;  1O71 A;  1KD6 A;  2L2B A;  4YLD A;  1GWY A;  4TSP A;  1Y2V A;  1Y2W A;  3QDS A;  3QDT A;  4Z2F A;  4Z2Q A;  4TSO A;  2OFC A; 
#chains in the Genus database with same CATH topology
 3ZWJ A;  4HPQ B;  1Y2T A;  3LIM A;  3W9P A;  2OFE A;  2KS4 A;  3QDU A;  3QDW A;  4TSY A;  3ZWG A;  5BPG A;  1Y2X A;  4WDC A;  4TSN A;  2OFD A;  2L38 A;  3A57 A;  4Z2S A;  1TZQ A;  3QDY A;  3VWI A;  1X99 A;  1XI0 A;  4TSQ A;  4WX5 A;  1Y2U A;  3QDX A;  3QDV A;  4TSL A;  1IAZ A;  1O72 A;  1O71 A;  1KD6 A;  2L2B A;  4YLD A;  1GWY A;  4OEB A;  4TSP A;  1Y2V A;  1Y2W A;  5JHF B;  3QDS A;  4P1W B;  3QDT A;  4Z2F A;  4Z2Q A;  4TSO A;  2OFC A;  4WX3 A;  4JOX A; 
#chains in the Genus database with same CATH homology
 3ZWJ A;  1Y2T A;  3LIM A;  3W9P A;  2OFE A;  2KS4 A;  3QDU A;  3QDW A;  4TSY A;  3ZWG A;  5BPG A;  1Y2X A;  4WDC A;  4TSN A;  2OFD A;  2L38 A;  4Z2S A;  1TZQ A;  3QDY A;  3VWI A;  1X99 A;  1XI0 A;  4TSQ A;  1Y2U A;  3QDX A;  3QDV A;  4TSL A;  1IAZ A;  1O72 A;  1O71 A;  1KD6 A;  2L2B A;  4YLD A;  1GWY A;  4TSP A;  1Y2V A;  1Y2W A;  3QDS A;  3QDT A;  4Z2F A;  4Z2Q A;  4TSO A;  2OFC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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