3SN2A

Crystal structure analysis of iron regulatory protein 1 in complex with transferrin receptor ire b rna
Total Genus 226
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
888
structure length
848
Chain Sequence
SNPFAYLAEPLDPAQPGKKFFNLNKLDYSRYGRLPFSIRVLLEAAVRNCDKFLVKKEDIENILNWNVTQHMNIEVPFKPARVILQDFTGVPSVVDFAAMRDAVKKLGGDPEKINPICPVDLVIDFERNRERFEFLKWGSKAFRNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGVLGWGVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATATFFPVDEVSIKYLVQTGRDESKVKQIRKYLQAVGMFRDYSDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPDHHNDHKTFIYNDSEFTLSHGSVVIAAITSSTNTSNPSVMLGAGLLAKKAVDAGLNVKPYVKTSLSPGSGVVTYYLRESGVMPYLSQLGFDVVPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGTNAKGQQVFLRDIWPTREEIQAVERQYVIPGMFTEVYQKIETVNASSDKLYLWNPKSTYIKSPPFFENLTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAIMARGTFANIRLLNRFLNKQAPQTIHLPSGETLDVFDAAERYQQEGHPLIVLAGKEYGSGSSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADSLGLTGRERYTIIIPENLTPRMHVQVKLDTGKTFQAVIRFDTDVELTYFHNGGILNYMIRKMAK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Accommodating variety in iron-responsive elements: Crystal structure of transferrin receptor 1 B IRE bound to iron regulatory protein 1.
pubmed doi rcsb
molecule tags Lyase/rna
source organism Oryctolagus cuniculus
molecule keywords Cytoplasmic aconitate hydratase
total genus 226
structure length 848
sequence length 888
ec nomenclature ec 4.2.1.3: Aconitate hydratase.
pdb deposition date 2011-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00330 Aconitase Aconitase family (aconitate hydratase)
A PF00694 Aconitase_C Aconitase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.19.10 Alpha Beta Alpha-Beta Barrel Aconitase; domain 4 Aconitase, domain 4 3sn2A03
3.30.499.10 Alpha Beta 2-Layer Sandwich Aconitase; domain 3 Aconitase, domain 3 3sn2A02
3.30.499.20 Alpha Beta 2-Layer Sandwich Aconitase; domain 3 Aconitase; domain 3 3sn2A01
1L5JA 1AMJA 2HCUA 6ACNA 1AMIA 4KP2A 3H5HA 1ACOA 3SNPA 2B3XA 3H5JA 2PKPA 1NITA 1V7LA 3Q3WA 3SN2A 4KP1A 1FGHA 1NISA 3H5EA 3VBAA 5ACNA 1C96A 4NQYA 1C97A 8ACNA 1B0JA 2B3YA 1B0KA 7ACNA 1B0MA
chains in the Genus database with same CATH superfamily
1L5JA 1AMJA 2HCUA 6ACNA 1AMIA 4KP2A 3H5HA 1ACOA 3SNPA 2B3XA 3H5JA 2PKPA 1NITA 1V7LA 3Q3WA 3SN2A 4KP1A 1FGHA 1NISA 3H5EA 3VBAA 5ACNA 1C96A 4NQYA 1C97A 8ACNA 1B0JA 2B3YA 1B0KA 7ACNA 1B0MA
chains in the Genus database with same CATH topology
1L5JA 1AMJA 2HCUA 6ACNA 1AMIA 4KP2A 3H5HA 1ACOA 3SNPA 2B3XA 3H5JA 2PKPA 1NITA 1V7LA 3Q3WA 3SN2A 4KP1A 1FGHA 1NISA 3H5EA 3VBAA 5ACNA 1C96A 4NQYA 1C97A 8ACNA 1B0JA 2B3YA 1B0KA 7ACNA 1B0MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L5J A;  1AMJ A;  2HCU A;  6ACN A;  1AMI A;  4KP2 A;  3H5H A;  1ACO A;  3SNP A;  2B3X A;  3H5J A;  2PKP A;  1NIT A;  1V7L A;  3Q3W A;  3SN2 A;  4KP1 A;  1FGH A;  1NIS A;  3H5E A;  3VBA A;  5ACN A;  1C96 A;  4NQY A;  1C97 A;  8ACN A;  1B0J A;  2B3Y A;  1B0K A;  7ACN A;  1B0M A; 
#chains in the Genus database with same CATH topology
 1L5J A;  1AMJ A;  2HCU A;  6ACN A;  1AMI A;  4KP2 A;  3H5H A;  1ACO A;  3SNP A;  2B3X A;  3H5J A;  2PKP A;  1NIT A;  1V7L A;  3Q3W A;  3SN2 A;  4KP1 A;  1FGH A;  1NIS A;  3H5E A;  3VBA A;  5ACN A;  1C96 A;  4NQY A;  1C97 A;  8ACN A;  1B0J A;  2B3Y A;  1B0K A;  7ACN A;  1B0M A; 
#chains in the Genus database with same CATH homology
 1L5J A;  1AMJ A;  2HCU A;  6ACN A;  1AMI A;  4KP2 A;  3H5H A;  1ACO A;  3SNP A;  2B3X A;  3H5J A;  2PKP A;  1NIT A;  1V7L A;  3Q3W A;  3SN2 A;  4KP1 A;  1FGH A;  1NIS A;  3H5E A;  3VBA A;  5ACN A;  1C96 A;  4NQY A;  1C97 A;  8ACN A;  1B0J A;  2B3Y A;  1B0K A;  7ACN A;  1B0M A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...