3TBJA

The 1.7a crystal structure of actibind a t2 ribonucleases as antitumorigenic agents
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
TIDTCSSDSPLSCQTDNEASCCFNSPGGSLLQTQFWDYDPSDGPSDSWTIHGLWPDNCDGTYQEYCDESREYSNITSILEAQNRTELLSYMKEYWPDYEGADEDESFWEHEWNKHGTCINTIEPSCYTDYYAQEEVGDFFQQVVDLFKTLDSYTALSDAGITPSEDATYKLSDIEDALAAIHDGYPPYVGCEDGALSQLYYYFNVKGSAIGGTYVASERLEDSNCKDSGIKYPPKYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The 1.8 A crystal structure of ACTIBIND suggests a mode of action for T2 ribonucleases as antitumorigenic agents.
pubmed doi rcsb
molecule keywords Actibind
molecule tags Hydrolase
total genus 74
structure length 237
sequence length 237
ec nomenclature
pdb deposition date 2011-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00445 Ribonuclease_T2 Ribonuclease T2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.730.10 Alpha Beta Alpha-Beta Complex Ribonuclease Rh; Chain A Ribonuclease T2-like 3tbjA00
4DVLA 3D3ZA 4DW3A 1VD1A 1IQQA 1BOLA 1J1FA 3TBJA 2PQXA 2PQYA 2Z70A 1JY5A 4DWAA 1DIXA 1V9HA 2EA1A 4DW5A 4DVNA 1UCDA 1VD3A 1VCZA 1BK7A 4DW4A 3T0OA 1IOOA 4DVKA 4DWCA 1IYBA 1UCAA 1J1GA 1UCCA 4DW7A 1UCGA 1SGLA
chains in the Genus database with same CATH superfamily
4DVLA 3D3ZA 4DW3A 1VD1A 1IQQA 1BOLA 1J1FA 3TBJA 2PQXA 2PQYA 2Z70A 1JY5A 4DWAA 1DIXA 1V9HA 2EA1A 4DW5A 4DVNA 1UCDA 1VD3A 1VCZA 1BK7A 4DW4A 3T0OA 1IOOA 4DVKA 4DWCA 1IYBA 1UCAA 1J1GA 1UCCA 4DW7A 1UCGA 1SGLA
chains in the Genus database with same CATH topology
4DVLA 3D3ZA 4DW3A 1VD1A 1IQQA 1BOLA 1J1FA 3TBJA 2PQXA 2PQYA 2Z70A 1JY5A 4DWAA 1DIXA 1V9HA 2EA1A 4DW5A 4DVNA 1UCDA 1VD3A 1VCZA 1BK7A 4DW4A 3T0OA 1IOOA 4DVKA 4DWCA 1IYBA 1UCAA 1J1GA 1UCCA 4DW7A 1UCGA 1SGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DVL A;  3D3Z A;  4DW3 A;  1VD1 A;  1IQQ A;  1BOL A;  1J1F A;  3TBJ A;  2PQX A;  2PQY A;  2Z70 A;  1JY5 A;  4DWA A;  1DIX A;  1V9H A;  2EA1 A;  4DW5 A;  4DVN A;  1UCD A;  1VD3 A;  1VCZ A;  1BK7 A;  4DW4 A;  3T0O A;  1IOO A;  4DVK A;  4DWC A;  1IYB A;  1UCA A;  1J1G A;  1UCC A;  4DW7 A;  1UCG A;  1SGL A; 
#chains in the Genus database with same CATH topology
 4DVL A;  3D3Z A;  4DW3 A;  1VD1 A;  1IQQ A;  1BOL A;  1J1F A;  3TBJ A;  2PQX A;  2PQY A;  2Z70 A;  1JY5 A;  4DWA A;  1DIX A;  1V9H A;  2EA1 A;  4DW5 A;  4DVN A;  1UCD A;  1VD3 A;  1VCZ A;  1BK7 A;  4DW4 A;  3T0O A;  1IOO A;  4DVK A;  4DWC A;  1IYB A;  1UCA A;  1J1G A;  1UCC A;  4DW7 A;  1UCG A;  1SGL A; 
#chains in the Genus database with same CATH homology
 4DVL A;  3D3Z A;  4DW3 A;  1VD1 A;  1IQQ A;  1BOL A;  1J1F A;  3TBJ A;  2PQX A;  2PQY A;  2Z70 A;  1JY5 A;  4DWA A;  1DIX A;  1V9H A;  2EA1 A;  4DW5 A;  4DVN A;  1UCD A;  1VD3 A;  1VCZ A;  1BK7 A;  4DW4 A;  3T0O A;  1IOO A;  4DVK A;  4DWC A;  1IYB A;  1UCA A;  1J1G A;  1UCC A;  4DW7 A;  1UCG A;  1SGL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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