3VWIA

High resolution crystal structure of frac in the monomeric form
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
177
structure length
177
Chain Sequence
DVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
pubmed doi rcsb
molecule tags Toxin
source organism Actinia fragacea
molecule keywords Fragaceatoxin C
total genus 50
structure length 177
sequence length 177
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2012-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 3vwiA00
2OFEA 4Z2FA 1Y2TA 3QDVA 1TZQA 4Z2SA 2OFDA 1IAZA 1Y2WA 4TSPA 3QDUA 3LIMA 3W9PA 1Y2VA 4WDCA 3QDWA 5BPGA 2L2BA 4TSOA 2KS4A 1O72A 3QDXA 3ZWJA 3ZWGA 2L38A 1Y2UA 3QDYA 1KD6A 4TSQA 4TSNA 4Z2QA 3QDSA 1X99A 3VWIA 1Y2XA 1GWYA 1XI0A 2OFCA 3QDTA 1O71A 4YLDA 4TSYA 4TSLA
chains in the Genus database with same CATH superfamily
2OFEA 4Z2FA 1Y2TA 3QDVA 1TZQA 4Z2SA 2OFDA 1IAZA 4WX3A 1Y2WA 4TSPA 3QDUA 3LIMA 3A57A 3W9PA 4OEBA 1Y2VA 4WDCA 3QDWA 5BPGA 2L2BA 4TSOA 2KS4A 1O72A 3QDXA 3ZWJA 3ZWGA 5JHFB 2L38A 1Y2UA 3QDYA 1KD6A 4P1WB 4TSQA 4TSNA 4WX5A 4Z2QA 3QDSA 1X99A 3VWIA 1Y2XA 1GWYA 1XI0A 2OFCA 3QDTA 1O71A 4YLDA 4TSYA 4TSLA 4HPQB 4JOXA
chains in the Genus database with same CATH topology
2OFEA 4Z2FA 1Y2TA 3QDVA 1TZQA 4Z2SA 2OFDA 1IAZA 1Y2WA 4TSPA 3QDUA 3LIMA 3W9PA 1Y2VA 4WDCA 3QDWA 5BPGA 2L2BA 4TSOA 2KS4A 1O72A 3QDXA 3ZWJA 3ZWGA 2L38A 1Y2UA 3QDYA 1KD6A 4TSQA 4TSNA 4Z2QA 3QDSA 1X99A 3VWIA 1Y2XA 1GWYA 1XI0A 2OFCA 3QDTA 1O71A 4YLDA 4TSYA 4TSLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OFE A;  4Z2F A;  1Y2T A;  3QDV A;  1TZQ A;  4Z2S A;  2OFD A;  1IAZ A;  1Y2W A;  4TSP A;  3QDU A;  3LIM A;  3W9P A;  1Y2V A;  4WDC A;  3QDW A;  5BPG A;  2L2B A;  4TSO A;  2KS4 A;  1O72 A;  3QDX A;  3ZWJ A;  3ZWG A;  2L38 A;  1Y2U A;  3QDY A;  1KD6 A;  4TSQ A;  4TSN A;  4Z2Q A;  3QDS A;  1X99 A;  3VWI A;  1Y2X A;  1GWY A;  1XI0 A;  2OFC A;  3QDT A;  1O71 A;  4YLD A;  4TSY A;  4TSL A; 
#chains in the Genus database with same CATH topology
 2OFE A;  4Z2F A;  1Y2T A;  3QDV A;  1TZQ A;  4Z2S A;  2OFD A;  1IAZ A;  4WX3 A;  1Y2W A;  4TSP A;  3QDU A;  3LIM A;  3A57 A;  3W9P A;  4OEB A;  1Y2V A;  4WDC A;  3QDW A;  5BPG A;  2L2B A;  4TSO A;  2KS4 A;  1O72 A;  3QDX A;  3ZWJ A;  3ZWG A;  5JHF B;  2L38 A;  1Y2U A;  3QDY A;  1KD6 A;  4P1W B;  4TSQ A;  4TSN A;  4WX5 A;  4Z2Q A;  3QDS A;  1X99 A;  3VWI A;  1Y2X A;  1GWY A;  1XI0 A;  2OFC A;  3QDT A;  1O71 A;  4YLD A;  4TSY A;  4TSL A;  4HPQ B;  4JOX A; 
#chains in the Genus database with same CATH homology
 2OFE A;  4Z2F A;  1Y2T A;  3QDV A;  1TZQ A;  4Z2S A;  2OFD A;  1IAZ A;  1Y2W A;  4TSP A;  3QDU A;  3LIM A;  3W9P A;  1Y2V A;  4WDC A;  3QDW A;  5BPG A;  2L2B A;  4TSO A;  2KS4 A;  1O72 A;  3QDX A;  3ZWJ A;  3ZWG A;  2L38 A;  1Y2U A;  3QDY A;  1KD6 A;  4TSQ A;  4TSN A;  4Z2Q A;  3QDS A;  1X99 A;  3VWI A;  1Y2X A;  1GWY A;  1XI0 A;  2OFC A;  3QDT A;  1O71 A;  4YLD A;  4TSY A;  4TSL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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