3SE8G

Crystal structure of broadly and potently neutralizing antibody vrc03 in complex with hiv-1 gp120
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
353
structure length
344
Chain Sequence
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEFFYCNTTQLFNNTCIGNMKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 Clade AE strain 93TH057 gp120
total genus 91
structure length 344
sequence length 353
ec nomenclature
pdb deposition date 2011-06-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 3se8G01
4RZ8A 4XVTG 3RJQA 4P9HG 5CD5A 4JM2E 3TGRA 1YYMG 4DVTA 5FECC 3SE9G 4DVRG 2NY7G 4YFLE 2NY0A 5FA2A 4LSVG 5KJRG 3JWOA 2QADA 4XVSG 2B4CG 2NXYA 5F96G 4DVXA 1RZKG 4RFOG 5F9OG 4XMPG 5T33G 1RZJG 4XNZA 4OM1G 4DKUA 5I9QA 5TE4G 5F4UA 4DVWA 3FUSA 4S1QG 4YDIG 3LQAG 5F4PA 4LSRG 4OLYG 1G9MG 4OLUG 4DKPA 4JDTG 4OLVG 4I54A 1G9NG 4YDKG 4LSSG 4LSPG 4R2GA 3IDXG 2NY3A 5IGXG 4RFNA 5TE7G 4OLZG 5CAYG 5F4RA 4JKPG 3TGQA 4XNYG 4R4NA 4JPWG 4RWYA 3JWDA 4YDLA 4R4FA 4JZWA 4LSQG 4H8WG 2BF1A 3TGSA 2I5YG 4KA2A 4JPVG 2NY6A 4DKOA 3HI1G 4JZZA 2I60G 4YDJG 3TIHA 4DKVA 2NY1A 4YE4G 4DKQA 4DVVA 2NY4A 4RX4E 4DVSA 4K0AA 3SE8G 2NXZA 4LSUG 3U7YG 5F9WA 5TE6G 1YYLG 4J6RG 2NY5G 4LAJA 4LSTG 1GC1G 4OLXG 4DKRA 4OLWG 4S1SG 4I53A 3TGTA 3IDYA 4OM0G 5F4LA 2NY2A 4JB9G 3NGBA 4S1RG
chains in the Genus database with same CATH superfamily
4RZ8A 4XVTG 3RJQA 4P9HG 5CD5A 4JM2E 3TGRA 1YYMG 4DVTA 5FECC 3SE9G 4DVRG 2NY7G 4YFLE 2NY0A 5FA2A 4LSVG 5KJRG 3JWOA 2QADA 4XVSG 2B4CG 2NXYA 5F96G 4DVXA 1RZKG 4RFOG 5F9OG 4XMPG 5T33G 1RZJG 4XNZA 4OM1G 4DKUA 5I9QA 5TE4G 5F4UA 4DVWA 3FUSA 4S1QG 4YDIG 3LQAG 5F4PA 4LSRG 4OLYG 1G9MG 4OLUG 4DKPA 4JDTG 4OLVG 4I54A 1G9NG 4YDKG 4LSSG 4LSPG 4R2GA 3IDXG 2NY3A 5IGXG 4RFNA 5TE7G 4OLZG 5CAYG 5F4RA 4JKPG 3TGQA 4XNYG 4R4NA 4JPWG 4RWYA 3JWDA 4YDLA 4R4FA 4JZWA 4LSQG 4H8WG 2BF1A 3TGSA 2I5YG 4KA2A 4JPVG 2NY6A 4DKOA 3HI1G 4JZZA 2I60G 4YDJG 3TIHA 4DKVA 2NY1A 4YE4G 4DKQA 4DVVA 2NY4A 4RX4E 4DVSA 4K0AA 3SE8G 2NXZA 4LSUG 3U7YG 5F9WA 5TE6G 1YYLG 4J6RG 2NY5G 4LAJA 4LSTG 1GC1G 4OLXG 4DKRA 4OLWG 4S1SG 4I53A 3TGTA 3IDYA 4OM0G 5F4LA 2NY2A 4JB9G 3NGBA 4S1RG
chains in the Genus database with same CATH topology
4RZ8A 4XVTG 3RJQA 4P9HG 5CD5A 4JM2E 3TGRA 1YYMG 4DVTA 5FECC 3SE9G 4DVRG 2NY7G 4YFLE 2NY0A 5FA2A 4LSVG 5KJRG 3JWOA 2QADA 4XVSG 2B4CG 2NXYA 5F96G 4DVXA 1RZKG 4RFOG 5F9OG 4XMPG 5T33G 1RZJG 4XNZA 4OM1G 4DKUA 5I9QA 5TE4G 5F4UA 4DVWA 3FUSA 4S1QG 4YDIG 3LQAG 5F4PA 4LSRG 4OLYG 1G9MG 4OLUG 4DKPA 4JDTG 4OLVG 4I54A 1G9NG 4YDKG 4LSSG 4LSPG 4R2GA 3IDXG 2NY3A 5IGXG 4RFNA 5TE7G 4OLZG 5CAYG 5F4RA 4JKPG 3TGQA 4XNYG 4R4NA 4JPWG 4RWYA 3JWDA 4YDLA 4R4FA 4JZWA 4LSQG 4H8WG 2BF1A 3TGSA 2I5YG 4KA2A 4JPVG 2NY6A 4DKOA 3HI1G 4JZZA 2I60G 4YDJG 3TIHA 4DKVA 2NY1A 4YE4G 4DKQA 4DVVA 2NY4A 4RX4E 4DVSA 4K0AA 3SE8G 2NXZA 4LSUG 3U7YG 5F9WA 5TE6G 1YYLG 4J6RG 2NY5G 4LAJA 4LSTG 1GC1G 4OLXG 4DKRA 4OLWG 4S1SG 4I53A 3TGTA 3IDYA 4OM0G 5F4LA 2NY2A 4JB9G 3NGBA 4S1RG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RZ8 A;  4XVT G;  3RJQ A;  4P9H G;  5CD5 A;  4JM2 E;  3TGR A;  1YYM G;  4DVT A;  5FEC C;  3SE9 G;  4DVR G;  2NY7 G;  4YFL E;  2NY0 A;  5FA2 A;  4LSV G;  5KJR G;  3JWO A;  2QAD A;  4XVS G;  2B4C G;  2NXY A;  5F96 G;  4DVX A;  1RZK G;  4RFO G;  5F9O G;  4XMP G;  5T33 G;  1RZJ G;  4XNZ A;  4OM1 G;  4DKU A;  5I9Q A;  5TE4 G;  5F4U A;  4DVW A;  3FUS A;  4S1Q G;  4YDI G;  3LQA G;  5F4P A;  4LSR G;  4OLY G;  1G9M G;  4OLU G;  4DKP A;  4JDT G;  4OLV G;  4I54 A;  1G9N G;  4YDK G;  4LSS G;  4LSP G;  4R2G A;  3IDX G;  2NY3 A;  5IGX G;  4RFN A;  5TE7 G;  4OLZ G;  5CAY G;  5F4R A;  4JKP G;  3TGQ A;  4XNY G;  4R4N A;  4JPW G;  4RWY A;  3JWD A;  4YDL A;  4R4F A;  4JZW A;  4LSQ G;  4H8W G;  2BF1 A;  3TGS A;  2I5Y G;  4KA2 A;  4JPV G;  2NY6 A;  4DKO A;  3HI1 G;  4JZZ A;  2I60 G;  4YDJ G;  3TIH A;  4DKV A;  2NY1 A;  4YE4 G;  4DKQ A;  4DVV A;  2NY4 A;  4RX4 E;  4DVS A;  4K0A A;  3SE8 G;  2NXZ A;  4LSU G;  3U7Y G;  5F9W A;  5TE6 G;  1YYL G;  4J6R G;  2NY5 G;  4LAJ A;  4LST G;  1GC1 G;  4OLX G;  4DKR A;  4OLW G;  4S1S G;  4I53 A;  3TGT A;  3IDY A;  4OM0 G;  5F4L A;  2NY2 A;  4JB9 G;  3NGB A;  4S1R G; 
#chains in the Genus database with same CATH topology
 4RZ8 A;  4XVT G;  3RJQ A;  4P9H G;  5CD5 A;  4JM2 E;  3TGR A;  1YYM G;  4DVT A;  5FEC C;  3SE9 G;  4DVR G;  2NY7 G;  4YFL E;  2NY0 A;  5FA2 A;  4LSV G;  5KJR G;  3JWO A;  2QAD A;  4XVS G;  2B4C G;  2NXY A;  5F96 G;  4DVX A;  1RZK G;  4RFO G;  5F9O G;  4XMP G;  5T33 G;  1RZJ G;  4XNZ A;  4OM1 G;  4DKU A;  5I9Q A;  5TE4 G;  5F4U A;  4DVW A;  3FUS A;  4S1Q G;  4YDI G;  3LQA G;  5F4P A;  4LSR G;  4OLY G;  1G9M G;  4OLU G;  4DKP A;  4JDT G;  4OLV G;  4I54 A;  1G9N G;  4YDK G;  4LSS G;  4LSP G;  4R2G A;  3IDX G;  2NY3 A;  5IGX G;  4RFN A;  5TE7 G;  4OLZ G;  5CAY G;  5F4R A;  4JKP G;  3TGQ A;  4XNY G;  4R4N A;  4JPW G;  4RWY A;  3JWD A;  4YDL A;  4R4F A;  4JZW A;  4LSQ G;  4H8W G;  2BF1 A;  3TGS A;  2I5Y G;  4KA2 A;  4JPV G;  2NY6 A;  4DKO A;  3HI1 G;  4JZZ A;  2I60 G;  4YDJ G;  3TIH A;  4DKV A;  2NY1 A;  4YE4 G;  4DKQ A;  4DVV A;  2NY4 A;  4RX4 E;  4DVS A;  4K0A A;  3SE8 G;  2NXZ A;  4LSU G;  3U7Y G;  5F9W A;  5TE6 G;  1YYL G;  4J6R G;  2NY5 G;  4LAJ A;  4LST G;  1GC1 G;  4OLX G;  4DKR A;  4OLW G;  4S1S G;  4I53 A;  3TGT A;  3IDY A;  4OM0 G;  5F4L A;  2NY2 A;  4JB9 G;  3NGB A;  4S1R G; 
#chains in the Genus database with same CATH homology
 4RZ8 A;  4XVT G;  3RJQ A;  4P9H G;  5CD5 A;  4JM2 E;  3TGR A;  1YYM G;  4DVT A;  5FEC C;  3SE9 G;  4DVR G;  2NY7 G;  4YFL E;  2NY0 A;  5FA2 A;  4LSV G;  5KJR G;  3JWO A;  2QAD A;  4XVS G;  2B4C G;  2NXY A;  5F96 G;  4DVX A;  1RZK G;  4RFO G;  5F9O G;  4XMP G;  5T33 G;  1RZJ G;  4XNZ A;  4OM1 G;  4DKU A;  5I9Q A;  5TE4 G;  5F4U A;  4DVW A;  3FUS A;  4S1Q G;  4YDI G;  3LQA G;  5F4P A;  4LSR G;  4OLY G;  1G9M G;  4OLU G;  4DKP A;  4JDT G;  4OLV G;  4I54 A;  1G9N G;  4YDK G;  4LSS G;  4LSP G;  4R2G A;  3IDX G;  2NY3 A;  5IGX G;  4RFN A;  5TE7 G;  4OLZ G;  5CAY G;  5F4R A;  4JKP G;  3TGQ A;  4XNY G;  4R4N A;  4JPW G;  4RWY A;  3JWD A;  4YDL A;  4R4F A;  4JZW A;  4LSQ G;  4H8W G;  2BF1 A;  3TGS A;  2I5Y G;  4KA2 A;  4JPV G;  2NY6 A;  4DKO A;  3HI1 G;  4JZZ A;  2I60 G;  4YDJ G;  3TIH A;  4DKV A;  2NY1 A;  4YE4 G;  4DKQ A;  4DVV A;  2NY4 A;  4RX4 E;  4DVS A;  4K0A A;  3SE8 G;  2NXZ A;  4LSU G;  3U7Y G;  5F9W A;  5TE6 G;  1YYL G;  4J6R G;  2NY5 G;  4LAJ A;  4LST G;  1GC1 G;  4OLX G;  4DKR A;  4OLW G;  4S1S G;  4I53 A;  3TGT A;  3IDY A;  4OM0 G;  5F4L A;  2NY2 A;  4JB9 G;  3NGB A;  4S1R G; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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