3SE9G

Crystal structure of broadly and potently neutralizing antibody vrc-pg04 in complex with hiv-1 gp120
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
353
structure length
344
Chain Sequence
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEFFYCNTTQLFNNTCIGMKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 Clade AE strain 93TH057 gp120
total genus 82
structure length 344
sequence length 353
ec nomenclature
pdb deposition date 2011-06-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 3se9G01
2NY1A 2I5YG 4YDJG 4RWYA 3HI1G 4JB9G 1YYLG 3IDXG 2NY6A 3IDYA 4J6RG 4LSVG 5CD5A 3TGQA 4OLWG 4OLYG 5FECC 3FUSA 4P9HG 4JPWG 4R2GA 3SE8G 2NY2A 4DKOA 1G9NG 4DVSA 4LSRG 2NY0A 4JDTG 4R4NA 4DVWA 4RX4E 4I54A 3SE9G 1RZKG 4OM0G 4S1RG 5F4UA 3TGSA 2I60G 4YE4G 4OLZG 4LAJA 5F9WA 4LSSG 4R4FA 4JM2E 4RFNA 3TGTA 4YDIG 4S1SG 4LSUG 5FA2A 4I53A 1GC1G 4OLVG 2NY3A 4DKUA 5CAYG 5I9QA 4OLXG 5T33G 4XNZA 4S1QG 4DKVA 5KJRG 4XMPG 5F4RA 4LSPG 3TIHA 4DVXA 2B4CG 3U7YG 2NXZA 1G9MG 2NY4A 4DVRG 3JWDA 5F4PA 5TE4G 5F96G 4YFLE 4LSQG 4JKPG 1YYMG 5F4LA 4DKPA 3LQAG 4JZWA 3JWOA 4DKQA 4XNYG 4YDKG 4LSTG 5IGXG 4RFOG 2QADA 3NGBA 4DVTA 4DKRA 4OM1G 4K0AA 4XVSG 4H8WG 2BF1A 4JPVG 4XVTG 5F9OG 1RZJG 2NY5G 5TE7G 4OLUG 4RZ8A 3RJQA 4YDLA 5TE6G 2NY7G 4JZZA 4KA2A 2NXYA 3TGRA 4DVVA
chains in the Genus database with same CATH superfamily
2NY1A 2I5YG 4YDJG 4RWYA 3HI1G 4JB9G 1YYLG 3IDXG 2NY6A 3IDYA 4J6RG 4LSVG 5CD5A 3TGQA 4OLWG 4OLYG 5FECC 3FUSA 4P9HG 4JPWG 4R2GA 3SE8G 2NY2A 4DKOA 1G9NG 4DVSA 4LSRG 2NY0A 4JDTG 4R4NA 4DVWA 4RX4E 4I54A 3SE9G 1RZKG 4OM0G 4S1RG 5F4UA 3TGSA 2I60G 4YE4G 4OLZG 4LAJA 5F9WA 4LSSG 4R4FA 4JM2E 4RFNA 3TGTA 4YDIG 4S1SG 4LSUG 5FA2A 4I53A 1GC1G 4OLVG 2NY3A 4DKUA 5CAYG 5I9QA 4OLXG 5T33G 4XNZA 4S1QG 4DKVA 5KJRG 4XMPG 5F4RA 4LSPG 3TIHA 4DVXA 2B4CG 3U7YG 2NXZA 1G9MG 2NY4A 4DVRG 3JWDA 5F4PA 5TE4G 5F96G 4YFLE 4LSQG 4JKPG 1YYMG 5F4LA 4DKPA 3LQAG 4JZWA 3JWOA 4DKQA 4XNYG 4YDKG 4LSTG 5IGXG 4RFOG 2QADA 3NGBA 4DVTA 4DKRA 4OM1G 4K0AA 4XVSG 4H8WG 2BF1A 4JPVG 4XVTG 5F9OG 1RZJG 2NY5G 5TE7G 4OLUG 4RZ8A 3RJQA 4YDLA 5TE6G 2NY7G 4JZZA 4KA2A 2NXYA 3TGRA 4DVVA
chains in the Genus database with same CATH topology
2NY1A 2I5YG 4YDJG 4RWYA 3HI1G 4JB9G 1YYLG 3IDXG 2NY6A 3IDYA 4J6RG 4LSVG 5CD5A 3TGQA 4OLWG 4OLYG 5FECC 3FUSA 4P9HG 4JPWG 4R2GA 3SE8G 2NY2A 4DKOA 1G9NG 4DVSA 4LSRG 2NY0A 4JDTG 4R4NA 4DVWA 4RX4E 4I54A 3SE9G 1RZKG 4OM0G 4S1RG 5F4UA 3TGSA 2I60G 4YE4G 4OLZG 4LAJA 5F9WA 4LSSG 4R4FA 4JM2E 4RFNA 3TGTA 4YDIG 4S1SG 4LSUG 5FA2A 4I53A 1GC1G 4OLVG 2NY3A 4DKUA 5CAYG 5I9QA 4OLXG 5T33G 4XNZA 4S1QG 4DKVA 5KJRG 4XMPG 5F4RA 4LSPG 3TIHA 4DVXA 2B4CG 3U7YG 2NXZA 1G9MG 2NY4A 4DVRG 3JWDA 5F4PA 5TE4G 5F96G 4YFLE 4LSQG 4JKPG 1YYMG 5F4LA 4DKPA 3LQAG 4JZWA 3JWOA 4DKQA 4XNYG 4YDKG 4LSTG 5IGXG 4RFOG 2QADA 3NGBA 4DVTA 4DKRA 4OM1G 4K0AA 4XVSG 4H8WG 2BF1A 4JPVG 4XVTG 5F9OG 1RZJG 2NY5G 5TE7G 4OLUG 4RZ8A 3RJQA 4YDLA 5TE6G 2NY7G 4JZZA 4KA2A 2NXYA 3TGRA 4DVVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NY1 A;  2I5Y G;  4YDJ G;  4RWY A;  3HI1 G;  4JB9 G;  1YYL G;  3IDX G;  2NY6 A;  3IDY A;  4J6R G;  4LSV G;  5CD5 A;  3TGQ A;  4OLW G;  4OLY G;  5FEC C;  3FUS A;  4P9H G;  4JPW G;  4R2G A;  3SE8 G;  2NY2 A;  4DKO A;  1G9N G;  4DVS A;  4LSR G;  2NY0 A;  4JDT G;  4R4N A;  4DVW A;  4RX4 E;  4I54 A;  3SE9 G;  1RZK G;  4OM0 G;  4S1R G;  5F4U A;  3TGS A;  2I60 G;  4YE4 G;  4OLZ G;  4LAJ A;  5F9W A;  4LSS G;  4R4F A;  4JM2 E;  4RFN A;  3TGT A;  4YDI G;  4S1S G;  4LSU G;  5FA2 A;  4I53 A;  1GC1 G;  4OLV G;  2NY3 A;  4DKU A;  5CAY G;  5I9Q A;  4OLX G;  5T33 G;  4XNZ A;  4S1Q G;  4DKV A;  5KJR G;  4XMP G;  5F4R A;  4LSP G;  3TIH A;  4DVX A;  2B4C G;  3U7Y G;  2NXZ A;  1G9M G;  2NY4 A;  4DVR G;  3JWD A;  5F4P A;  5TE4 G;  5F96 G;  4YFL E;  4LSQ G;  4JKP G;  1YYM G;  5F4L A;  4DKP A;  3LQA G;  4JZW A;  3JWO A;  4DKQ A;  4XNY G;  4YDK G;  4LST G;  5IGX G;  4RFO G;  2QAD A;  3NGB A;  4DVT A;  4DKR A;  4OM1 G;  4K0A A;  4XVS G;  4H8W G;  2BF1 A;  4JPV G;  4XVT G;  5F9O G;  1RZJ G;  2NY5 G;  5TE7 G;  4OLU G;  4RZ8 A;  3RJQ A;  4YDL A;  5TE6 G;  2NY7 G;  4JZZ A;  4KA2 A;  2NXY A;  3TGR A;  4DVV A; 
#chains in the Genus database with same CATH topology
 2NY1 A;  2I5Y G;  4YDJ G;  4RWY A;  3HI1 G;  4JB9 G;  1YYL G;  3IDX G;  2NY6 A;  3IDY A;  4J6R G;  4LSV G;  5CD5 A;  3TGQ A;  4OLW G;  4OLY G;  5FEC C;  3FUS A;  4P9H G;  4JPW G;  4R2G A;  3SE8 G;  2NY2 A;  4DKO A;  1G9N G;  4DVS A;  4LSR G;  2NY0 A;  4JDT G;  4R4N A;  4DVW A;  4RX4 E;  4I54 A;  3SE9 G;  1RZK G;  4OM0 G;  4S1R G;  5F4U A;  3TGS A;  2I60 G;  4YE4 G;  4OLZ G;  4LAJ A;  5F9W A;  4LSS G;  4R4F A;  4JM2 E;  4RFN A;  3TGT A;  4YDI G;  4S1S G;  4LSU G;  5FA2 A;  4I53 A;  1GC1 G;  4OLV G;  2NY3 A;  4DKU A;  5CAY G;  5I9Q A;  4OLX G;  5T33 G;  4XNZ A;  4S1Q G;  4DKV A;  5KJR G;  4XMP G;  5F4R A;  4LSP G;  3TIH A;  4DVX A;  2B4C G;  3U7Y G;  2NXZ A;  1G9M G;  2NY4 A;  4DVR G;  3JWD A;  5F4P A;  5TE4 G;  5F96 G;  4YFL E;  4LSQ G;  4JKP G;  1YYM G;  5F4L A;  4DKP A;  3LQA G;  4JZW A;  3JWO A;  4DKQ A;  4XNY G;  4YDK G;  4LST G;  5IGX G;  4RFO G;  2QAD A;  3NGB A;  4DVT A;  4DKR A;  4OM1 G;  4K0A A;  4XVS G;  4H8W G;  2BF1 A;  4JPV G;  4XVT G;  5F9O G;  1RZJ G;  2NY5 G;  5TE7 G;  4OLU G;  4RZ8 A;  3RJQ A;  4YDL A;  5TE6 G;  2NY7 G;  4JZZ A;  4KA2 A;  2NXY A;  3TGR A;  4DVV A; 
#chains in the Genus database with same CATH homology
 2NY1 A;  2I5Y G;  4YDJ G;  4RWY A;  3HI1 G;  4JB9 G;  1YYL G;  3IDX G;  2NY6 A;  3IDY A;  4J6R G;  4LSV G;  5CD5 A;  3TGQ A;  4OLW G;  4OLY G;  5FEC C;  3FUS A;  4P9H G;  4JPW G;  4R2G A;  3SE8 G;  2NY2 A;  4DKO A;  1G9N G;  4DVS A;  4LSR G;  2NY0 A;  4JDT G;  4R4N A;  4DVW A;  4RX4 E;  4I54 A;  3SE9 G;  1RZK G;  4OM0 G;  4S1R G;  5F4U A;  3TGS A;  2I60 G;  4YE4 G;  4OLZ G;  4LAJ A;  5F9W A;  4LSS G;  4R4F A;  4JM2 E;  4RFN A;  3TGT A;  4YDI G;  4S1S G;  4LSU G;  5FA2 A;  4I53 A;  1GC1 G;  4OLV G;  2NY3 A;  4DKU A;  5CAY G;  5I9Q A;  4OLX G;  5T33 G;  4XNZ A;  4S1Q G;  4DKV A;  5KJR G;  4XMP G;  5F4R A;  4LSP G;  3TIH A;  4DVX A;  2B4C G;  3U7Y G;  2NXZ A;  1G9M G;  2NY4 A;  4DVR G;  3JWD A;  5F4P A;  5TE4 G;  5F96 G;  4YFL E;  4LSQ G;  4JKP G;  1YYM G;  5F4L A;  4DKP A;  3LQA G;  4JZW A;  3JWO A;  4DKQ A;  4XNY G;  4YDK G;  4LST G;  5IGX G;  4RFO G;  2QAD A;  3NGB A;  4DVT A;  4DKR A;  4OM1 G;  4K0A A;  4XVS G;  4H8W G;  2BF1 A;  4JPV G;  4XVT G;  5F9O G;  1RZJ G;  2NY5 G;  5TE7 G;  4OLU G;  4RZ8 A;  3RJQ A;  4YDL A;  5TE6 G;  2NY7 G;  4JZZ A;  4KA2 A;  2NXY A;  3TGR A;  4DVV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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