4AA6A

The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
71
structure length
69
Chain Sequence
TRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Oestrogen Receptor Recognizes an Imperfectly Palindromic Response Element Through an Alternative Side-Chain Conformation.
pubmed rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords ESTROGEN RECEPTOR
total genus 13
structure length 69
sequence length 71
chains with identical sequence B, E, F
ec nomenclature
pdb deposition date 2011-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 4aa6A00
1RXRA 4OV7A 3DZYA 4HCAA 3G8UA 3VD6C 1RGDA 1CITA 1R0NA 1HLZA 4HC7A 2NLLB 1YNWB 5EMCA 5CC1A 1A6YA 5E6AA 3DFXA 1GDCA 3G9OA 2ENVA 5CBYA 1R4OA 5CC0A 3M9EA 2KAEA 3E00D 3G6QA 3G99A 3G8XA 3G9PA 1KB4A 2VUUI 5E69A 2EBLA 2C7AA 3DZUD 3G6RA 5EMQA 1DSZB 1HRAA 2NLLA 3E00A 1YNWA 4ONDA 5E6CA 3G6TA 1BY4A 4CN3D 2GATA 1R0OB 5CBXA 4HN6A 2HANB 4CN5A 1HCPA 5CBZA 3DZUA 5E6DA 1KB2A 2FF0A 2M9WA 2A66A 1R0OA 2VUSI 1GAUA 2GDAA 4OLNA 3FYLA 1LATA 5EMPA 1GATA 4CN2C 4NQAB 4CN3A 1R0NB 2VUTI 3G9MA 3G9IA 5KRBB 3GATA 3G97A 3G9JA 1R4RA 1GA5A 4GATA 1HCQA 5E6BA 4TNTA 4CN7A 1GLUA 3VEKC 4OORA 3G6UA 7GATA 3DFVC 6GATA 1LV3A 1DSZA 3DZYD 4HC9A 4HN5A 1GNFA 1LO1A 4AA6A 3G6PA 3CBBA 4TMAI 5L0MA 1KB6A 2HANA 4IQRA 5GATA 1R4IA
chains in the Genus database with same CATH superfamily
1RXRA 4OV7A 3DZYA 4HCAA 3G8UA 3VD6C 1RGDA 1CITA 1R0NA 1HLZA 4HC7A 2NLLB 1YNWB 2DS5A 5EMCA 5CC1A 1A6YA 5E6AA 3DFXA 1GDCA 3G9OA 2ENVA 5CBYA 1R4OA 5CC0A 3M9EA 2KAEA 3E00D 2DS6A 3G6QA 3G99A 3G8XA 3G9PA 1KB4A 2VUUI 5E69A 2EBLA 2C7AA 3DZUD 3G6RA 5EMQA 1DSZB 1HRAA 2DS8A 2NLLA 3E00A 1YNWA 3G27A 4ONDA 5E6CA 3G6TA 1BY4A 4CN3D 2GATA 1R0OB 5CBXA 4HN6A 2HANB 4CN5A 1HCPA 5CBZA 3DZUA 5E6DA 1KB2A 2FF0A 2M9WA 2A66A 1R0OA 2VUSI 1GAUA 2GDAA 4OLNA 3FYLA 1LATA 5EMPA 1GATA 4CN2C 4NQAB 4CN3A 1R0NB 2VUTI 3G9MA 3G9IA 5KRBB 3GATA 3G97A 3G9JA 1R4RA 1GA5A 4GATA 1HCQA 5E6BA 4TNTA 4CN7A 1GLUA 3VEKC 4OORA 3G6UA 7GATA 3DFVC 6GATA 1LV3A 1DSZA 3DZYD 4HC9A 4HN5A 1GNFA 1LO1A 4AA6A 3G6PA 3CBBA 4TMAI 5L0MA 1KB6A 2HANA 4IQRA 5GATA 1R4IA
chains in the Genus database with same CATH topology
1RXRA 4OV7A 3DZYA 4HCAA 3G8UA 3VD6C 1RGDA 1CITA 1R0NA 1HLZA 4HC7A 2NLLB 1YNWB 5EMCA 5CC1A 1A6YA 5E6AA 3DFXA 1GDCA 3G9OA 2ENVA 5CBYA 1R4OA 5CC0A 3M9EA 2KAEA 3E00D 3G6QA 3G99A 3G8XA 3G9PA 1KB4A 2VUUI 5E69A 2EBLA 2C7AA 3DZUD 3G6RA 5EMQA 1DSZB 1HRAA 2NLLA 3E00A 1YNWA 4ONDA 5E6CA 3G6TA 1BY4A 4CN3D 2GATA 1R0OB 5CBXA 4HN6A 2HANB 4CN5A 1HCPA 5CBZA 3DZUA 5E6DA 1KB2A 2FF0A 2M9WA 2A66A 1R0OA 2VUSI 1GAUA 2GDAA 4OLNA 3FYLA 1LATA 5EMPA 1GATA 4CN2C 4NQAB 4CN3A 1R0NB 2VUTI 3G9MA 3G9IA 5KRBB 3GATA 3G97A 3G9JA 1R4RA 1GA5A 4GATA 1HCQA 5E6BA 4TNTA 4CN7A 1GLUA 3VEKC 4OORA 3G6UA 7GATA 3DFVC 6GATA 1LV3A 1DSZA 3DZYD 4HC9A 4HN5A 1GNFA 1LO1A 4AA6A 3G6PA 3CBBA 4TMAI 5L0MA 1KB6A 2HANA 4IQRA 5GATA 1R4IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RXR A;  4OV7 A;  3DZY A;  4HCA A;  3G8U A;  3VD6 C;  1RGD A;  1CIT A;  1R0N A;  1HLZ A;  4HC7 A;  2NLL B;  1YNW B;  5EMC A;  5CC1 A;  1A6Y A;  5E6A A;  3DFX A;  1GDC A;  3G9O A;  2ENV A;  5CBY A;  1R4O A;  5CC0 A;  3M9E A;  2KAE A;  3E00 D;  3G6Q A;  3G99 A;  3G8X A;  3G9P A;  1KB4 A;  2VUU I;  5E69 A;  2EBL A;  2C7A A;  3DZU D;  3G6R A;  5EMQ A;  1DSZ B;  1HRA A;  2NLL A;  3E00 A;  1YNW A;  4OND A;  5E6C A;  3G6T A;  1BY4 A;  4CN3 D;  2GAT A;  1R0O B;  5CBX A;  4HN6 A;  2HAN B;  4CN5 A;  1HCP A;  5CBZ A;  3DZU A;  5E6D A;  1KB2 A;  2FF0 A;  2M9W A;  2A66 A;  1R0O A;  2VUS I;  1GAU A;  2GDA A;  4OLN A;  3FYL A;  1LAT A;  5EMP A;  1GAT A;  4CN2 C;  4NQA B;  4CN3 A;  1R0N B;  2VUT I;  3G9M A;  3G9I A;  5KRB B;  3GAT A;  3G97 A;  3G9J A;  1R4R A;  1GA5 A;  4GAT A;  1HCQ A;  5E6B A;  4TNT A;  4CN7 A;  1GLU A;  3VEK C;  4OOR A;  3G6U A;  7GAT A;  3DFV C;  6GAT A;  1LV3 A;  1DSZ A;  3DZY D;  4HC9 A;  4HN5 A;  1GNF A;  1LO1 A;  4AA6 A;  3G6P A;  3CBB A;  4TMA I;  5L0M A;  1KB6 A;  2HAN A;  4IQR A;  5GAT A;  1R4I A; 
#chains in the Genus database with same CATH topology
 1RXR A;  4OV7 A;  3DZY A;  4HCA A;  3G8U A;  3VD6 C;  1RGD A;  1CIT A;  1R0N A;  1HLZ A;  4HC7 A;  2NLL B;  1YNW B;  2DS5 A;  5EMC A;  5CC1 A;  1A6Y A;  5E6A A;  3DFX A;  1GDC A;  3G9O A;  2ENV A;  5CBY A;  1R4O A;  5CC0 A;  3M9E A;  2KAE A;  3E00 D;  2DS6 A;  3G6Q A;  3G99 A;  3G8X A;  3G9P A;  1KB4 A;  2VUU I;  5E69 A;  2EBL A;  2C7A A;  3DZU D;  3G6R A;  5EMQ A;  1DSZ B;  1HRA A;  2DS8 A;  2NLL A;  3E00 A;  1YNW A;  3G27 A;  4OND A;  5E6C A;  3G6T A;  1BY4 A;  4CN3 D;  2GAT A;  1R0O B;  5CBX A;  4HN6 A;  2HAN B;  4CN5 A;  1HCP A;  5CBZ A;  3DZU A;  5E6D A;  1KB2 A;  2FF0 A;  2M9W A;  2A66 A;  1R0O A;  2VUS I;  1GAU A;  2GDA A;  4OLN A;  3FYL A;  1LAT A;  5EMP A;  1GAT A;  4CN2 C;  4NQA B;  4CN3 A;  1R0N B;  2VUT I;  3G9M A;  3G9I A;  5KRB B;  3GAT A;  3G97 A;  3G9J A;  1R4R A;  1GA5 A;  4GAT A;  1HCQ A;  5E6B A;  4TNT A;  4CN7 A;  1GLU A;  3VEK C;  4OOR A;  3G6U A;  7GAT A;  3DFV C;  6GAT A;  1LV3 A;  1DSZ A;  3DZY D;  4HC9 A;  4HN5 A;  1GNF A;  1LO1 A;  4AA6 A;  3G6P A;  3CBB A;  4TMA I;  5L0M A;  1KB6 A;  2HAN A;  4IQR A;  5GAT A;  1R4I A; 
#chains in the Genus database with same CATH homology
 1RXR A;  4OV7 A;  3DZY A;  4HCA A;  3G8U A;  3VD6 C;  1RGD A;  1CIT A;  1R0N A;  1HLZ A;  4HC7 A;  2NLL B;  1YNW B;  5EMC A;  5CC1 A;  1A6Y A;  5E6A A;  3DFX A;  1GDC A;  3G9O A;  2ENV A;  5CBY A;  1R4O A;  5CC0 A;  3M9E A;  2KAE A;  3E00 D;  3G6Q A;  3G99 A;  3G8X A;  3G9P A;  1KB4 A;  2VUU I;  5E69 A;  2EBL A;  2C7A A;  3DZU D;  3G6R A;  5EMQ A;  1DSZ B;  1HRA A;  2NLL A;  3E00 A;  1YNW A;  4OND A;  5E6C A;  3G6T A;  1BY4 A;  4CN3 D;  2GAT A;  1R0O B;  5CBX A;  4HN6 A;  2HAN B;  4CN5 A;  1HCP A;  5CBZ A;  3DZU A;  5E6D A;  1KB2 A;  2FF0 A;  2M9W A;  2A66 A;  1R0O A;  2VUS I;  1GAU A;  2GDA A;  4OLN A;  3FYL A;  1LAT A;  5EMP A;  1GAT A;  4CN2 C;  4NQA B;  4CN3 A;  1R0N B;  2VUT I;  3G9M A;  3G9I A;  5KRB B;  3GAT A;  3G97 A;  3G9J A;  1R4R A;  1GA5 A;  4GAT A;  1HCQ A;  5E6B A;  4TNT A;  4CN7 A;  1GLU A;  3VEK C;  4OOR A;  3G6U A;  7GAT A;  3DFV C;  6GAT A;  1LV3 A;  1DSZ A;  3DZY D;  4HC9 A;  4HN5 A;  1GNF A;  1LO1 A;  4AA6 A;  3G6P A;  3CBB A;  4TMA I;  5L0M A;  1KB6 A;  2HAN A;  4IQR A;  5GAT A;  1R4I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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