4BSOA

Crystal structure of r-spondin 1 (fu1fu2) - native
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
106
structure length
97
Chain Sequence
QACAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPMECS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
molecule keywords R-SPONDIN-1
total genus 19
structure length 97
sequence length 106
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bsoA00
4P59A 3I2TA 1IVOA 1N8ZC 3LTFA 4UFRB 2AHXA 4KT1E 3BE1A 3B2VA 4XSSE 4BSRC 4C9AB 1YY9A 4KRPA 4C9EB 3LTGA 2HR7A 1N8YC 1IGRA 1MOXA 3NJPA 4UV7A 4BSSC 2A91A 4C99B 4C9VB 4CDKE 4LEOC 4OGAE 4C8VA 4C9RB 4C9UB 3W11E 4C8WI 4LI2B 4XSTE 3U2PA 3U7UA 3N85A 5J3HE 1NQLA 4BSUC 4QXFC 3U9UE 1S78A 4HRNC 4KROA 4BSPA 3MZWA 4BSOA 3WSQA 3P11A 3QWQA 4KNGM 1M6BA 3WLWA
chains in the Genus database with same CATH superfamily
4P59A 3I2TA 1IVOA 1N8ZC 3LTFA 4UFRB 2AHXA 4KT1E 3BE1A 3B2VA 4XSSE 4BSRC 4C9AB 1YY9A 4KRPA 4C9EB 3LTGA 2HR7A 1N8YC 1IGRA 1MOXA 3NJPA 4UV7A 4BSSC 2A91A 4C99B 4C9VB 4CDKE 4LEOC 4OGAE 4C8VA 4C9RB 4C9UB 3W11E 4C8WI 4LI2B 4XSTE 3U2PA 3U7UA 3N85A 5J3HE 1NQLA 4BSUC 4QXFC 3U9UE 1S78A 4HRNC 4KROA 4BSPA 3MZWA 4BSOA 3WSQA 3P11A 3QWQA 4KNGM 1M6BA 3WLWA
chains in the Genus database with same CATH topology
4P59A 3I2TA 1IVOA 1N8ZC 3LTFA 4UFRB 2AHXA 4KT1E 3BE1A 3B2VA 4XSSE 4BSRC 4C9AB 1YY9A 4KRPA 4C9EB 3LTGA 2HR7A 1N8YC 1IGRA 1MOXA 3NJPA 4UV7A 4BSSC 2A91A 4C99B 4C9VB 4CDKE 4LEOC 4OGAE 4C8VA 4C9RB 4C9UB 3W11E 4C8WI 4LI2B 4XSTE 3U2PA 3U7UA 3N85A 5J3HE 1NQLA 4BSUC 4QXFC 3U9UE 1S78A 4HRNC 4KROA 4BSPA 3MZWA 4BSOA 3WSQA 3P11A 3QWQA 4KNGM 1M6BA 3WLWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P59 A;  3I2T A;  1IVO A;  1N8Z C;  3LTF A;  4UFR B;  2AHX A;  4KT1 E;  3BE1 A;  3B2V A;  4XSS E;  4BSR C;  4C9A B;  1YY9 A;  4KRP A;  4C9E B;  3LTG A;  2HR7 A;  1N8Y C;  1IGR A;  1MOX A;  3NJP A;  4UV7 A;  4BSS C;  2A91 A;  4C99 B;  4C9V B;  4CDK E;  4LEO C;  4OGA E;  4C8V A;  4C9R B;  4C9U B;  3W11 E;  4C8W I;  4LI2 B;  4XST E;  3U2P A;  3U7U A;  3N85 A;  5J3H E;  1NQL A;  4BSU C;  4QXF C;  3U9U E;  1S78 A;  4HRN C;  4KRO A;  4BSP A;  3MZW A;  4BSO A;  3WSQ A;  3P11 A;  3QWQ A;  4KNG M;  1M6B A;  3WLW A; 
#chains in the Genus database with same CATH topology
 4P59 A;  3I2T A;  1IVO A;  1N8Z C;  3LTF A;  4UFR B;  2AHX A;  4KT1 E;  3BE1 A;  3B2V A;  4XSS E;  4BSR C;  4C9A B;  1YY9 A;  4KRP A;  4C9E B;  3LTG A;  2HR7 A;  1N8Y C;  1IGR A;  1MOX A;  3NJP A;  4UV7 A;  4BSS C;  2A91 A;  4C99 B;  4C9V B;  4CDK E;  4LEO C;  4OGA E;  4C8V A;  4C9R B;  4C9U B;  3W11 E;  4C8W I;  4LI2 B;  4XST E;  3U2P A;  3U7U A;  3N85 A;  5J3H E;  1NQL A;  4BSU C;  4QXF C;  3U9U E;  1S78 A;  4HRN C;  4KRO A;  4BSP A;  3MZW A;  4BSO A;  3WSQ A;  3P11 A;  3QWQ A;  4KNG M;  1M6B A;  3WLW A; 
#chains in the Genus database with same CATH homology
 4P59 A;  3I2T A;  1IVO A;  1N8Z C;  3LTF A;  4UFR B;  2AHX A;  4KT1 E;  3BE1 A;  3B2V A;  4XSS E;  4BSR C;  4C9A B;  1YY9 A;  4KRP A;  4C9E B;  3LTG A;  2HR7 A;  1N8Y C;  1IGR A;  1MOX A;  3NJP A;  4UV7 A;  4BSS C;  2A91 A;  4C99 B;  4C9V B;  4CDK E;  4LEO C;  4OGA E;  4C8V A;  4C9R B;  4C9U B;  3W11 E;  4C8W I;  4LI2 B;  4XST E;  3U2P A;  3U7U A;  3N85 A;  5J3H E;  1NQL A;  4BSU C;  4QXF C;  3U9U E;  1S78 A;  4HRN C;  4KRO A;  4BSP A;  3MZW A;  4BSO A;  3WSQ A;  3P11 A;  3QWQ A;  4KNG M;  1M6B A;  3WLW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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