4BSPA

Crystal structure of r-spondin 1 (fu1fu2) - holmium soak
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
88
structure length
88
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
molecule keywords R-SPONDIN-1
total genus 11
structure length 88
sequence length 88
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bspA00
3LTGA 4BSOA 3I2TA 3U2PA 3WLWA 1N8ZC 4HRNC 4LEOC 3U9UE 4XSTE 3WSQA 4C8WI 1NQLA 4KNGM 5J3HE 4BSRC 1S78A 3U7UA 1N8YC 3MZWA 4C9UB 1M6BA 4C99B 4KRPA 1MOXA 2AHXA 4C9AB 1IGRA 4KROA 3P11A 4XSSE 4C9EB 1IVOA 4BSSC 3W11E 3QWQA 3B2VA 3BE1A 4UFRB 3NJPA 4P59A 4BSUC 4BSPA 4LI2B 4KT1E 1YY9A 3N85A 4OGAE 4QXFC 4C8VA 4C9RB 4C9VB 4UV7A 3LTFA 2A91A 4CDKE 2HR7A
chains in the Genus database with same CATH superfamily
3LTGA 4BSOA 3I2TA 3U2PA 3WLWA 1N8ZC 4HRNC 4LEOC 3U9UE 4XSTE 3WSQA 4C8WI 1NQLA 4KNGM 5J3HE 4BSRC 1S78A 3U7UA 1N8YC 3MZWA 4C9UB 1M6BA 4C99B 4KRPA 1MOXA 2AHXA 4C9AB 1IGRA 4KROA 3P11A 4XSSE 4C9EB 1IVOA 4BSSC 3W11E 3QWQA 3B2VA 3BE1A 4UFRB 3NJPA 4P59A 4BSUC 4BSPA 4LI2B 4KT1E 1YY9A 3N85A 4OGAE 4QXFC 4C8VA 4C9RB 4C9VB 4UV7A 3LTFA 2A91A 4CDKE 2HR7A
chains in the Genus database with same CATH topology
3LTGA 4BSOA 3I2TA 3U2PA 3WLWA 1N8ZC 4HRNC 4LEOC 3U9UE 4XSTE 3WSQA 4C8WI 1NQLA 4KNGM 5J3HE 4BSRC 1S78A 3U7UA 1N8YC 3MZWA 4C9UB 1M6BA 4C99B 4KRPA 1MOXA 2AHXA 4C9AB 1IGRA 4KROA 3P11A 4XSSE 4C9EB 1IVOA 4BSSC 3W11E 3QWQA 3B2VA 3BE1A 4UFRB 3NJPA 4P59A 4BSUC 4BSPA 4LI2B 4KT1E 1YY9A 3N85A 4OGAE 4QXFC 4C8VA 4C9RB 4C9VB 4UV7A 3LTFA 2A91A 4CDKE 2HR7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LTG A;  4BSO A;  3I2T A;  3U2P A;  3WLW A;  1N8Z C;  4HRN C;  4LEO C;  3U9U E;  4XST E;  3WSQ A;  4C8W I;  1NQL A;  4KNG M;  5J3H E;  4BSR C;  1S78 A;  3U7U A;  1N8Y C;  3MZW A;  4C9U B;  1M6B A;  4C99 B;  4KRP A;  1MOX A;  2AHX A;  4C9A B;  1IGR A;  4KRO A;  3P11 A;  4XSS E;  4C9E B;  1IVO A;  4BSS C;  3W11 E;  3QWQ A;  3B2V A;  3BE1 A;  4UFR B;  3NJP A;  4P59 A;  4BSU C;  4BSP A;  4LI2 B;  4KT1 E;  1YY9 A;  3N85 A;  4OGA E;  4QXF C;  4C8V A;  4C9R B;  4C9V B;  4UV7 A;  3LTF A;  2A91 A;  4CDK E;  2HR7 A; 
#chains in the Genus database with same CATH topology
 3LTG A;  4BSO A;  3I2T A;  3U2P A;  3WLW A;  1N8Z C;  4HRN C;  4LEO C;  3U9U E;  4XST E;  3WSQ A;  4C8W I;  1NQL A;  4KNG M;  5J3H E;  4BSR C;  1S78 A;  3U7U A;  1N8Y C;  3MZW A;  4C9U B;  1M6B A;  4C99 B;  4KRP A;  1MOX A;  2AHX A;  4C9A B;  1IGR A;  4KRO A;  3P11 A;  4XSS E;  4C9E B;  1IVO A;  4BSS C;  3W11 E;  3QWQ A;  3B2V A;  3BE1 A;  4UFR B;  3NJP A;  4P59 A;  4BSU C;  4BSP A;  4LI2 B;  4KT1 E;  1YY9 A;  3N85 A;  4OGA E;  4QXF C;  4C8V A;  4C9R B;  4C9V B;  4UV7 A;  3LTF A;  2A91 A;  4CDK E;  2HR7 A; 
#chains in the Genus database with same CATH homology
 3LTG A;  4BSO A;  3I2T A;  3U2P A;  3WLW A;  1N8Z C;  4HRN C;  4LEO C;  3U9U E;  4XST E;  3WSQ A;  4C8W I;  1NQL A;  4KNG M;  5J3H E;  4BSR C;  1S78 A;  3U7U A;  1N8Y C;  3MZW A;  4C9U B;  1M6B A;  4C99 B;  4KRP A;  1MOX A;  2AHX A;  4C9A B;  1IGR A;  4KRO A;  3P11 A;  4XSS E;  4C9E B;  1IVO A;  4BSS C;  3W11 E;  3QWQ A;  3B2V A;  3BE1 A;  4UFR B;  3NJP A;  4P59 A;  4BSU C;  4BSP A;  4LI2 B;  4KT1 E;  1YY9 A;  3N85 A;  4OGA E;  4QXF C;  4C8V A;  4C9R B;  4C9V B;  4UV7 A;  3LTF A;  2A91 A;  4CDK E;  2HR7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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