4BSRC

Structure of the ectodomain of lgr5 in complex with r-spondin-1 (fu1fu2) in p22121 crystal form
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
103
structure length
103
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
molecule keywords LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5
total genus 17
structure length 103
sequence length 103
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bsrC00
3NJPA 3U7UA 4LEOC 3MZWA 4C9UB 2AHXA 4UV7A 1N8YC 4KNGM 3B2VA 3LTFA 4C9VB 1NQLA 4BSSC 1YY9A 4P59A 3BE1A 4KT1E 4QXFC 4BSOA 4KRPA 4C9EB 2A91A 4C9AB 4CDKE 3U2PA 1M6BA 2HR7A 3W11E 3P11A 4UFRB 4XSTE 4C9RB 3LTGA 4HRNC 3N85A 3U9UE 4BSPA 4OGAE 4KROA 1N8ZC 1IVOA 3WSQA 1IGRA 1S78A 5J3HE 4C8WI 4C8VA 1MOXA 4C99B 3WLWA 4XSSE 4BSRC 3QWQA 3I2TA 4BSUC 4LI2B
chains in the Genus database with same CATH superfamily
3NJPA 3U7UA 4LEOC 3MZWA 4C9UB 2AHXA 4UV7A 1N8YC 4KNGM 3B2VA 3LTFA 4C9VB 1NQLA 4BSSC 1YY9A 4P59A 3BE1A 4KT1E 4QXFC 4BSOA 4KRPA 4C9EB 2A91A 4C9AB 4CDKE 3U2PA 1M6BA 2HR7A 3W11E 3P11A 4UFRB 4XSTE 4C9RB 3LTGA 4HRNC 3N85A 3U9UE 4BSPA 4OGAE 4KROA 1N8ZC 1IVOA 3WSQA 1IGRA 1S78A 5J3HE 4C8WI 4C8VA 1MOXA 4C99B 3WLWA 4XSSE 4BSRC 3QWQA 3I2TA 4BSUC 4LI2B
chains in the Genus database with same CATH topology
3NJPA 3U7UA 4LEOC 3MZWA 4C9UB 2AHXA 4UV7A 1N8YC 4KNGM 3B2VA 3LTFA 4C9VB 1NQLA 4BSSC 1YY9A 4P59A 3BE1A 4KT1E 4QXFC 4BSOA 4KRPA 4C9EB 2A91A 4C9AB 4CDKE 3U2PA 1M6BA 2HR7A 3W11E 3P11A 4UFRB 4XSTE 4C9RB 3LTGA 4HRNC 3N85A 3U9UE 4BSPA 4OGAE 4KROA 1N8ZC 1IVOA 3WSQA 1IGRA 1S78A 5J3HE 4C8WI 4C8VA 1MOXA 4C99B 3WLWA 4XSSE 4BSRC 3QWQA 3I2TA 4BSUC 4LI2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NJP A;  3U7U A;  4LEO C;  3MZW A;  4C9U B;  2AHX A;  4UV7 A;  1N8Y C;  4KNG M;  3B2V A;  3LTF A;  4C9V B;  1NQL A;  4BSS C;  1YY9 A;  4P59 A;  3BE1 A;  4KT1 E;  4QXF C;  4BSO A;  4KRP A;  4C9E B;  2A91 A;  4C9A B;  4CDK E;  3U2P A;  1M6B A;  2HR7 A;  3W11 E;  3P11 A;  4UFR B;  4XST E;  4C9R B;  3LTG A;  4HRN C;  3N85 A;  3U9U E;  4BSP A;  4OGA E;  4KRO A;  1N8Z C;  1IVO A;  3WSQ A;  1IGR A;  1S78 A;  5J3H E;  4C8W I;  4C8V A;  1MOX A;  4C99 B;  3WLW A;  4XSS E;  4BSR C;  3QWQ A;  3I2T A;  4BSU C;  4LI2 B; 
#chains in the Genus database with same CATH topology
 3NJP A;  3U7U A;  4LEO C;  3MZW A;  4C9U B;  2AHX A;  4UV7 A;  1N8Y C;  4KNG M;  3B2V A;  3LTF A;  4C9V B;  1NQL A;  4BSS C;  1YY9 A;  4P59 A;  3BE1 A;  4KT1 E;  4QXF C;  4BSO A;  4KRP A;  4C9E B;  2A91 A;  4C9A B;  4CDK E;  3U2P A;  1M6B A;  2HR7 A;  3W11 E;  3P11 A;  4UFR B;  4XST E;  4C9R B;  3LTG A;  4HRN C;  3N85 A;  3U9U E;  4BSP A;  4OGA E;  4KRO A;  1N8Z C;  1IVO A;  3WSQ A;  1IGR A;  1S78 A;  5J3H E;  4C8W I;  4C8V A;  1MOX A;  4C99 B;  3WLW A;  4XSS E;  4BSR C;  3QWQ A;  3I2T A;  4BSU C;  4LI2 B; 
#chains in the Genus database with same CATH homology
 3NJP A;  3U7U A;  4LEO C;  3MZW A;  4C9U B;  2AHX A;  4UV7 A;  1N8Y C;  4KNG M;  3B2V A;  3LTF A;  4C9V B;  1NQL A;  4BSS C;  1YY9 A;  4P59 A;  3BE1 A;  4KT1 E;  4QXF C;  4BSO A;  4KRP A;  4C9E B;  2A91 A;  4C9A B;  4CDK E;  3U2P A;  1M6B A;  2HR7 A;  3W11 E;  3P11 A;  4UFR B;  4XST E;  4C9R B;  3LTG A;  4HRN C;  3N85 A;  3U9U E;  4BSP A;  4OGA E;  4KRO A;  1N8Z C;  1IVO A;  3WSQ A;  1IGR A;  1S78 A;  5J3H E;  4C8W I;  4C8V A;  1MOX A;  4C99 B;  3WLW A;  4XSS E;  4BSR C;  3QWQ A;  3I2T A;  4BSU C;  4LI2 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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