4BSRC

Structure of the ectodomain of lgr5 in complex with r-spondin-1 (fu1fu2) in p22121 crystal form
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
103
structure length
103
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5
total genus 17
structure length 103
sequence length 103
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bsrC00
1S78A 4C99B 2AHXA 1YY9A 3NJPA 4QXFC 1IVOA 4XSSE 4KROA 3I2TA 4P59A 3BE1A 4UFRB 4KNGM 3U7UA 4C9EB 1N8YC 4C8WI 4C9AB 4LI2B 4HRNC 4OGAE 4LEOC 3B2VA 4BSRC 3N85A 4BSPA 4UV7A 3WLWA 3WSQA 1MOXA 1IGRA 3LTFA 4C8VA 4XSTE 4KT1E 1NQLA 2HR7A 4BSOA 4C9UB 1M6BA 3P11A 4CDKE 4C9RB 4C9VB 1N8ZC 4BSUC 4KRPA 3QWQA 3U2PA 3U9UE 3MZWA 3LTGA 4BSSC 3W11E 5J3HE 2A91A
chains in the Genus database with same CATH superfamily
1S78A 4C99B 2AHXA 1YY9A 3NJPA 4QXFC 1IVOA 4XSSE 4KROA 3I2TA 4P59A 3BE1A 4UFRB 4KNGM 3U7UA 4C9EB 1N8YC 4C8WI 4C9AB 4LI2B 4HRNC 4OGAE 4LEOC 3B2VA 4BSRC 3N85A 4BSPA 4UV7A 3WLWA 3WSQA 1MOXA 1IGRA 3LTFA 4C8VA 4XSTE 4KT1E 1NQLA 2HR7A 4BSOA 4C9UB 1M6BA 3P11A 4CDKE 4C9RB 4C9VB 1N8ZC 4BSUC 4KRPA 3QWQA 3U2PA 3U9UE 3MZWA 3LTGA 4BSSC 3W11E 5J3HE 2A91A
chains in the Genus database with same CATH topology
1S78A 4C99B 2AHXA 1YY9A 3NJPA 4QXFC 1IVOA 4XSSE 4KROA 3I2TA 4P59A 3BE1A 4UFRB 4KNGM 3U7UA 4C9EB 1N8YC 4C8WI 4C9AB 4LI2B 4HRNC 4OGAE 4LEOC 3B2VA 4BSRC 3N85A 4BSPA 4UV7A 3WLWA 3WSQA 1MOXA 1IGRA 3LTFA 4C8VA 4XSTE 4KT1E 1NQLA 2HR7A 4BSOA 4C9UB 1M6BA 3P11A 4CDKE 4C9RB 4C9VB 1N8ZC 4BSUC 4KRPA 3QWQA 3U2PA 3U9UE 3MZWA 3LTGA 4BSSC 3W11E 5J3HE 2A91A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S78 A;  4C99 B;  2AHX A;  1YY9 A;  3NJP A;  4QXF C;  1IVO A;  4XSS E;  4KRO A;  3I2T A;  4P59 A;  3BE1 A;  4UFR B;  4KNG M;  3U7U A;  4C9E B;  1N8Y C;  4C8W I;  4C9A B;  4LI2 B;  4HRN C;  4OGA E;  4LEO C;  3B2V A;  4BSR C;  3N85 A;  4BSP A;  4UV7 A;  3WLW A;  3WSQ A;  1MOX A;  1IGR A;  3LTF A;  4C8V A;  4XST E;  4KT1 E;  1NQL A;  2HR7 A;  4BSO A;  4C9U B;  1M6B A;  3P11 A;  4CDK E;  4C9R B;  4C9V B;  1N8Z C;  4BSU C;  4KRP A;  3QWQ A;  3U2P A;  3U9U E;  3MZW A;  3LTG A;  4BSS C;  3W11 E;  5J3H E;  2A91 A; 
#chains in the Genus database with same CATH topology
 1S78 A;  4C99 B;  2AHX A;  1YY9 A;  3NJP A;  4QXF C;  1IVO A;  4XSS E;  4KRO A;  3I2T A;  4P59 A;  3BE1 A;  4UFR B;  4KNG M;  3U7U A;  4C9E B;  1N8Y C;  4C8W I;  4C9A B;  4LI2 B;  4HRN C;  4OGA E;  4LEO C;  3B2V A;  4BSR C;  3N85 A;  4BSP A;  4UV7 A;  3WLW A;  3WSQ A;  1MOX A;  1IGR A;  3LTF A;  4C8V A;  4XST E;  4KT1 E;  1NQL A;  2HR7 A;  4BSO A;  4C9U B;  1M6B A;  3P11 A;  4CDK E;  4C9R B;  4C9V B;  1N8Z C;  4BSU C;  4KRP A;  3QWQ A;  3U2P A;  3U9U E;  3MZW A;  3LTG A;  4BSS C;  3W11 E;  5J3H E;  2A91 A; 
#chains in the Genus database with same CATH homology
 1S78 A;  4C99 B;  2AHX A;  1YY9 A;  3NJP A;  4QXF C;  1IVO A;  4XSS E;  4KRO A;  3I2T A;  4P59 A;  3BE1 A;  4UFR B;  4KNG M;  3U7U A;  4C9E B;  1N8Y C;  4C8W I;  4C9A B;  4LI2 B;  4HRN C;  4OGA E;  4LEO C;  3B2V A;  4BSR C;  3N85 A;  4BSP A;  4UV7 A;  3WLW A;  3WSQ A;  1MOX A;  1IGR A;  3LTF A;  4C8V A;  4XST E;  4KT1 E;  1NQL A;  2HR7 A;  4BSO A;  4C9U B;  1M6B A;  3P11 A;  4CDK E;  4C9R B;  4C9V B;  1N8Z C;  4BSU C;  4KRP A;  3QWQ A;  3U2P A;  3U9U E;  3MZW A;  3LTG A;  4BSS C;  3W11 E;  5J3H E;  2A91 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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