4BSSC

Structure of the ectodomain of lgr5 in complex with r-spondin-1 (fu1fu2) in p21 crystal form
Total Genus 14
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
103
structure length
103
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMEC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5
total genus 14
structure length 103
sequence length 103
chains with identical sequence D, G, H
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bssC00
4BSSC 3LTFA 4LI2B 4BSUC 4C9UB 2A91A 4BSOA 1IVOA 1IGRA 3W11E 2AHXA 3U2PA 4C9EB 1S78A 3I2TA 3MZWA 3N85A 4QXFC 4KNGM 3WSQA 1M6BA 1N8YC 3QWQA 4UV7A 5J3HE 4BSRC 3U7UA 3BE1A 1YY9A 4HRNC 2HR7A 3U9UE 4UFRB 4C8WI 3B2VA 3LTGA 4KROA 4XSTE 4LEOC 4C9RB 4KT1E 4C8VA 4C9AB 4P59A 4KRPA 1N8ZC 3NJPA 4CDKE 4XSSE 4BSPA 3P11A 4C9VB 1NQLA 3WLWA 4C99B 1MOXA 4OGAE
chains in the Genus database with same CATH superfamily
4BSSC 3LTFA 4LI2B 4BSUC 4C9UB 2A91A 4BSOA 1IVOA 1IGRA 3W11E 2AHXA 3U2PA 4C9EB 1S78A 3I2TA 3MZWA 3N85A 4QXFC 4KNGM 3WSQA 1M6BA 1N8YC 3QWQA 4UV7A 5J3HE 4BSRC 3U7UA 3BE1A 1YY9A 4HRNC 2HR7A 3U9UE 4UFRB 4C8WI 3B2VA 3LTGA 4KROA 4XSTE 4LEOC 4C9RB 4KT1E 4C8VA 4C9AB 4P59A 4KRPA 1N8ZC 3NJPA 4CDKE 4XSSE 4BSPA 3P11A 4C9VB 1NQLA 3WLWA 4C99B 1MOXA 4OGAE
chains in the Genus database with same CATH topology
4BSSC 3LTFA 4LI2B 4BSUC 4C9UB 2A91A 4BSOA 1IVOA 1IGRA 3W11E 2AHXA 3U2PA 4C9EB 1S78A 3I2TA 3MZWA 3N85A 4QXFC 4KNGM 3WSQA 1M6BA 1N8YC 3QWQA 4UV7A 5J3HE 4BSRC 3U7UA 3BE1A 1YY9A 4HRNC 2HR7A 3U9UE 4UFRB 4C8WI 3B2VA 3LTGA 4KROA 4XSTE 4LEOC 4C9RB 4KT1E 4C8VA 4C9AB 4P59A 4KRPA 1N8ZC 3NJPA 4CDKE 4XSSE 4BSPA 3P11A 4C9VB 1NQLA 3WLWA 4C99B 1MOXA 4OGAE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BSS C;  3LTF A;  4LI2 B;  4BSU C;  4C9U B;  2A91 A;  4BSO A;  1IVO A;  1IGR A;  3W11 E;  2AHX A;  3U2P A;  4C9E B;  1S78 A;  3I2T A;  3MZW A;  3N85 A;  4QXF C;  4KNG M;  3WSQ A;  1M6B A;  1N8Y C;  3QWQ A;  4UV7 A;  5J3H E;  4BSR C;  3U7U A;  3BE1 A;  1YY9 A;  4HRN C;  2HR7 A;  3U9U E;  4UFR B;  4C8W I;  3B2V A;  3LTG A;  4KRO A;  4XST E;  4LEO C;  4C9R B;  4KT1 E;  4C8V A;  4C9A B;  4P59 A;  4KRP A;  1N8Z C;  3NJP A;  4CDK E;  4XSS E;  4BSP A;  3P11 A;  4C9V B;  1NQL A;  3WLW A;  4C99 B;  1MOX A;  4OGA E; 
#chains in the Genus database with same CATH topology
 4BSS C;  3LTF A;  4LI2 B;  4BSU C;  4C9U B;  2A91 A;  4BSO A;  1IVO A;  1IGR A;  3W11 E;  2AHX A;  3U2P A;  4C9E B;  1S78 A;  3I2T A;  3MZW A;  3N85 A;  4QXF C;  4KNG M;  3WSQ A;  1M6B A;  1N8Y C;  3QWQ A;  4UV7 A;  5J3H E;  4BSR C;  3U7U A;  3BE1 A;  1YY9 A;  4HRN C;  2HR7 A;  3U9U E;  4UFR B;  4C8W I;  3B2V A;  3LTG A;  4KRO A;  4XST E;  4LEO C;  4C9R B;  4KT1 E;  4C8V A;  4C9A B;  4P59 A;  4KRP A;  1N8Z C;  3NJP A;  4CDK E;  4XSS E;  4BSP A;  3P11 A;  4C9V B;  1NQL A;  3WLW A;  4C99 B;  1MOX A;  4OGA E; 
#chains in the Genus database with same CATH homology
 4BSS C;  3LTF A;  4LI2 B;  4BSU C;  4C9U B;  2A91 A;  4BSO A;  1IVO A;  1IGR A;  3W11 E;  2AHX A;  3U2P A;  4C9E B;  1S78 A;  3I2T A;  3MZW A;  3N85 A;  4QXF C;  4KNG M;  3WSQ A;  1M6B A;  1N8Y C;  3QWQ A;  4UV7 A;  5J3H E;  4BSR C;  3U7U A;  3BE1 A;  1YY9 A;  4HRN C;  2HR7 A;  3U9U E;  4UFR B;  4C8W I;  3B2V A;  3LTG A;  4KRO A;  4XST E;  4LEO C;  4C9R B;  4KT1 E;  4C8V A;  4C9A B;  4P59 A;  4KRP A;  1N8Z C;  3NJP A;  4CDK E;  4XSS E;  4BSP A;  3P11 A;  4C9V B;  1NQL A;  3WLW A;  4C99 B;  1MOX A;  4OGA E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...