4BSUC

Structure of the ectodomain of lgr5 in complex with r-spondin-1 (fu1fu2) in c2 crystal form
Total Genus 16
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
103
structure length
103
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMEC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5
total genus 16
structure length 103
sequence length 103
chains with identical sequence D, G, H
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bsuC00
4KNGM 4UFRB 4KRPA 4C9AB 4BSUC 3WSQA 3NJPA 3U7UA 3P11A 4BSOA 2A91A 1NQLA 3LTGA 4XSTE 4C8WI 3U9UE 1S78A 5J3HE 3U2PA 4C9VB 4C9EB 4BSSC 1IGRA 3QWQA 1N8ZC 4UV7A 2HR7A 1M6BA 4XSSE 4KT1E 4C9RB 3W11E 4CDKE 4LEOC 4OGAE 3I2TA 1IVOA 4P59A 4LI2B 3B2VA 3N85A 4C99B 4BSRC 1YY9A 3MZWA 4C8VA 4HRNC 1MOXA 4KROA 1N8YC 2AHXA 4BSPA 3WLWA 4C9UB 4QXFC 3LTFA 3BE1A
chains in the Genus database with same CATH superfamily
4KNGM 4UFRB 4KRPA 4C9AB 4BSUC 3WSQA 3NJPA 3U7UA 3P11A 4BSOA 2A91A 1NQLA 3LTGA 4XSTE 4C8WI 3U9UE 1S78A 5J3HE 3U2PA 4C9VB 4C9EB 4BSSC 1IGRA 3QWQA 1N8ZC 4UV7A 2HR7A 1M6BA 4XSSE 4KT1E 4C9RB 3W11E 4CDKE 4LEOC 4OGAE 3I2TA 1IVOA 4P59A 4LI2B 3B2VA 3N85A 4C99B 4BSRC 1YY9A 3MZWA 4C8VA 4HRNC 1MOXA 4KROA 1N8YC 2AHXA 4BSPA 3WLWA 4C9UB 4QXFC 3LTFA 3BE1A
chains in the Genus database with same CATH topology
4KNGM 4UFRB 4KRPA 4C9AB 4BSUC 3WSQA 3NJPA 3U7UA 3P11A 4BSOA 2A91A 1NQLA 3LTGA 4XSTE 4C8WI 3U9UE 1S78A 5J3HE 3U2PA 4C9VB 4C9EB 4BSSC 1IGRA 3QWQA 1N8ZC 4UV7A 2HR7A 1M6BA 4XSSE 4KT1E 4C9RB 3W11E 4CDKE 4LEOC 4OGAE 3I2TA 1IVOA 4P59A 4LI2B 3B2VA 3N85A 4C99B 4BSRC 1YY9A 3MZWA 4C8VA 4HRNC 1MOXA 4KROA 1N8YC 2AHXA 4BSPA 3WLWA 4C9UB 4QXFC 3LTFA 3BE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KNG M;  4UFR B;  4KRP A;  4C9A B;  4BSU C;  3WSQ A;  3NJP A;  3U7U A;  3P11 A;  4BSO A;  2A91 A;  1NQL A;  3LTG A;  4XST E;  4C8W I;  3U9U E;  1S78 A;  5J3H E;  3U2P A;  4C9V B;  4C9E B;  4BSS C;  1IGR A;  3QWQ A;  1N8Z C;  4UV7 A;  2HR7 A;  1M6B A;  4XSS E;  4KT1 E;  4C9R B;  3W11 E;  4CDK E;  4LEO C;  4OGA E;  3I2T A;  1IVO A;  4P59 A;  4LI2 B;  3B2V A;  3N85 A;  4C99 B;  4BSR C;  1YY9 A;  3MZW A;  4C8V A;  4HRN C;  1MOX A;  4KRO A;  1N8Y C;  2AHX A;  4BSP A;  3WLW A;  4C9U B;  4QXF C;  3LTF A;  3BE1 A; 
#chains in the Genus database with same CATH topology
 4KNG M;  4UFR B;  4KRP A;  4C9A B;  4BSU C;  3WSQ A;  3NJP A;  3U7U A;  3P11 A;  4BSO A;  2A91 A;  1NQL A;  3LTG A;  4XST E;  4C8W I;  3U9U E;  1S78 A;  5J3H E;  3U2P A;  4C9V B;  4C9E B;  4BSS C;  1IGR A;  3QWQ A;  1N8Z C;  4UV7 A;  2HR7 A;  1M6B A;  4XSS E;  4KT1 E;  4C9R B;  3W11 E;  4CDK E;  4LEO C;  4OGA E;  3I2T A;  1IVO A;  4P59 A;  4LI2 B;  3B2V A;  3N85 A;  4C99 B;  4BSR C;  1YY9 A;  3MZW A;  4C8V A;  4HRN C;  1MOX A;  4KRO A;  1N8Y C;  2AHX A;  4BSP A;  3WLW A;  4C9U B;  4QXF C;  3LTF A;  3BE1 A; 
#chains in the Genus database with same CATH homology
 4KNG M;  4UFR B;  4KRP A;  4C9A B;  4BSU C;  3WSQ A;  3NJP A;  3U7U A;  3P11 A;  4BSO A;  2A91 A;  1NQL A;  3LTG A;  4XST E;  4C8W I;  3U9U E;  1S78 A;  5J3H E;  3U2P A;  4C9V B;  4C9E B;  4BSS C;  1IGR A;  3QWQ A;  1N8Z C;  4UV7 A;  2HR7 A;  1M6B A;  4XSS E;  4KT1 E;  4C9R B;  3W11 E;  4CDK E;  4LEO C;  4OGA E;  3I2T A;  1IVO A;  4P59 A;  4LI2 B;  3B2V A;  3N85 A;  4C99 B;  4BSR C;  1YY9 A;  3MZW A;  4C8V A;  4HRN C;  1MOX A;  4KRO A;  1N8Y C;  2AHX A;  4BSP A;  3WLW A;  4C9U B;  4QXF C;  3LTF A;  3BE1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...