4BSUC

Structure of the ectodomain of lgr5 in complex with r-spondin-1 (fu1fu2) in c2 crystal form
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
103
structure length
103
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
molecule keywords LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5
total genus 16
structure length 103
sequence length 103
chains with identical sequence D, G, H
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bsuC00
4XSTE 4OGAE 1S78A 1IVOA 1MOXA 3U2PA 3WSQA 3W11E 4C8VA 1N8ZC 4BSOA 4KNGM 4C9UB 1NQLA 4BSSC 4CDKE 3N85A 3MZWA 4HRNC 4LEOC 3LTFA 3WLWA 1YY9A 4KRPA 1N8YC 3U9UE 3I2TA 5J3HE 4QXFC 4XSSE 3LTGA 4BSRC 4C99B 3BE1A 4P59A 4BSUC 3NJPA 2AHXA 4C8WI 1IGRA 1M6BA 4UV7A 4LI2B 2A91A 4KT1E 4KROA 4BSPA 3QWQA 3B2VA 3P11A 4C9RB 4C9VB 4C9EB 3U7UA 2HR7A 4UFRB 4C9AB
chains in the Genus database with same CATH superfamily
4XSTE 4OGAE 1S78A 1IVOA 1MOXA 3U2PA 3WSQA 3W11E 4C8VA 1N8ZC 4BSOA 4KNGM 4C9UB 1NQLA 4BSSC 4CDKE 3N85A 3MZWA 4HRNC 4LEOC 3LTFA 3WLWA 1YY9A 4KRPA 1N8YC 3U9UE 3I2TA 5J3HE 4QXFC 4XSSE 3LTGA 4BSRC 4C99B 3BE1A 4P59A 4BSUC 3NJPA 2AHXA 4C8WI 1IGRA 1M6BA 4UV7A 4LI2B 2A91A 4KT1E 4KROA 4BSPA 3QWQA 3B2VA 3P11A 4C9RB 4C9VB 4C9EB 3U7UA 2HR7A 4UFRB 4C9AB
chains in the Genus database with same CATH topology
4XSTE 4OGAE 1S78A 1IVOA 1MOXA 3U2PA 3WSQA 3W11E 4C8VA 1N8ZC 4BSOA 4KNGM 4C9UB 1NQLA 4BSSC 4CDKE 3N85A 3MZWA 4HRNC 4LEOC 3LTFA 3WLWA 1YY9A 4KRPA 1N8YC 3U9UE 3I2TA 5J3HE 4QXFC 4XSSE 3LTGA 4BSRC 4C99B 3BE1A 4P59A 4BSUC 3NJPA 2AHXA 4C8WI 1IGRA 1M6BA 4UV7A 4LI2B 2A91A 4KT1E 4KROA 4BSPA 3QWQA 3B2VA 3P11A 4C9RB 4C9VB 4C9EB 3U7UA 2HR7A 4UFRB 4C9AB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XST E;  4OGA E;  1S78 A;  1IVO A;  1MOX A;  3U2P A;  3WSQ A;  3W11 E;  4C8V A;  1N8Z C;  4BSO A;  4KNG M;  4C9U B;  1NQL A;  4BSS C;  4CDK E;  3N85 A;  3MZW A;  4HRN C;  4LEO C;  3LTF A;  3WLW A;  1YY9 A;  4KRP A;  1N8Y C;  3U9U E;  3I2T A;  5J3H E;  4QXF C;  4XSS E;  3LTG A;  4BSR C;  4C99 B;  3BE1 A;  4P59 A;  4BSU C;  3NJP A;  2AHX A;  4C8W I;  1IGR A;  1M6B A;  4UV7 A;  4LI2 B;  2A91 A;  4KT1 E;  4KRO A;  4BSP A;  3QWQ A;  3B2V A;  3P11 A;  4C9R B;  4C9V B;  4C9E B;  3U7U A;  2HR7 A;  4UFR B;  4C9A B; 
#chains in the Genus database with same CATH topology
 4XST E;  4OGA E;  1S78 A;  1IVO A;  1MOX A;  3U2P A;  3WSQ A;  3W11 E;  4C8V A;  1N8Z C;  4BSO A;  4KNG M;  4C9U B;  1NQL A;  4BSS C;  4CDK E;  3N85 A;  3MZW A;  4HRN C;  4LEO C;  3LTF A;  3WLW A;  1YY9 A;  4KRP A;  1N8Y C;  3U9U E;  3I2T A;  5J3H E;  4QXF C;  4XSS E;  3LTG A;  4BSR C;  4C99 B;  3BE1 A;  4P59 A;  4BSU C;  3NJP A;  2AHX A;  4C8W I;  1IGR A;  1M6B A;  4UV7 A;  4LI2 B;  2A91 A;  4KT1 E;  4KRO A;  4BSP A;  3QWQ A;  3B2V A;  3P11 A;  4C9R B;  4C9V B;  4C9E B;  3U7U A;  2HR7 A;  4UFR B;  4C9A B; 
#chains in the Genus database with same CATH homology
 4XST E;  4OGA E;  1S78 A;  1IVO A;  1MOX A;  3U2P A;  3WSQ A;  3W11 E;  4C8V A;  1N8Z C;  4BSO A;  4KNG M;  4C9U B;  1NQL A;  4BSS C;  4CDK E;  3N85 A;  3MZW A;  4HRN C;  4LEO C;  3LTF A;  3WLW A;  1YY9 A;  4KRP A;  1N8Y C;  3U9U E;  3I2T A;  5J3H E;  4QXF C;  4XSS E;  3LTG A;  4BSR C;  4C99 B;  3BE1 A;  4P59 A;  4BSU C;  3NJP A;  2AHX A;  4C8W I;  1IGR A;  1M6B A;  4UV7 A;  4LI2 B;  2A91 A;  4KT1 E;  4KRO A;  4BSP A;  3QWQ A;  3B2V A;  3P11 A;  4C9R B;  4C9V B;  4C9E B;  3U7U A;  2HR7 A;  4UFR B;  4C9A B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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