4C8WI

Xenopus rspo2 fu1-fu2 crystal form ii
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
104
structure length
104
Chain Sequence
ICKGCLSCSKDNGCLRCQPKLFFYLRREGMRQYGECLQSCPPGYYGVRGPDMNRCSRCRIENCDSCFSRDFCIKCKSGFYSHKGQCFEECPEGFAPLDDTMVCV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
pubmed doi rcsb
molecule tags Signaling protein
source organism Xenopus (silurana) tropicalis
molecule keywords R-SPONDIN-2
total genus 12
structure length 104
sequence length 104
chains with identical sequence J
ec nomenclature
pdb deposition date 2013-10-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4c8wI00
4LEOC 3U7UA 2AHXA 4KROA 4BSPA 4XSSE 3W11E 4BSRC 3P11A 3LTGA 4LI2B 1YY9A 4C9EB 2HR7A 3WSQA 3QWQA 3U2PA 1IVOA 2A91A 4KT1E 3BE1A 1NQLA 4KRPA 3N85A 4UFRB 4UV7A 4OGAE 4BSUC 4C8WI 1N8YC 4C9AB 4CDKE 4BSOA 4BSSC 1S78A 3I2TA 4XSTE 3LTFA 3MZWA 4P59A 4HRNC 3B2VA 1MOXA 4QXFC 4C9VB 4C8VA 4C9RB 1N8ZC 1M6BA 5J3HE 3NJPA 3U9UE 1IGRA 4C9UB 3WLWA 4KNGM 4C99B
chains in the Genus database with same CATH superfamily
4LEOC 3U7UA 2AHXA 4KROA 4BSPA 4XSSE 3W11E 4BSRC 3P11A 3LTGA 4LI2B 1YY9A 4C9EB 2HR7A 3WSQA 3QWQA 3U2PA 1IVOA 2A91A 4KT1E 3BE1A 1NQLA 4KRPA 3N85A 4UFRB 4UV7A 4OGAE 4BSUC 4C8WI 1N8YC 4C9AB 4CDKE 4BSOA 4BSSC 1S78A 3I2TA 4XSTE 3LTFA 3MZWA 4P59A 4HRNC 3B2VA 1MOXA 4QXFC 4C9VB 4C8VA 4C9RB 1N8ZC 1M6BA 5J3HE 3NJPA 3U9UE 1IGRA 4C9UB 3WLWA 4KNGM 4C99B
chains in the Genus database with same CATH topology
4LEOC 3U7UA 2AHXA 4KROA 4BSPA 4XSSE 3W11E 4BSRC 3P11A 3LTGA 4LI2B 1YY9A 4C9EB 2HR7A 3WSQA 3QWQA 3U2PA 1IVOA 2A91A 4KT1E 3BE1A 1NQLA 4KRPA 3N85A 4UFRB 4UV7A 4OGAE 4BSUC 4C8WI 1N8YC 4C9AB 4CDKE 4BSOA 4BSSC 1S78A 3I2TA 4XSTE 3LTFA 3MZWA 4P59A 4HRNC 3B2VA 1MOXA 4QXFC 4C9VB 4C8VA 4C9RB 1N8ZC 1M6BA 5J3HE 3NJPA 3U9UE 1IGRA 4C9UB 3WLWA 4KNGM 4C99B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LEO C;  3U7U A;  2AHX A;  4KRO A;  4BSP A;  4XSS E;  3W11 E;  4BSR C;  3P11 A;  3LTG A;  4LI2 B;  1YY9 A;  4C9E B;  2HR7 A;  3WSQ A;  3QWQ A;  3U2P A;  1IVO A;  2A91 A;  4KT1 E;  3BE1 A;  1NQL A;  4KRP A;  3N85 A;  4UFR B;  4UV7 A;  4OGA E;  4BSU C;  4C8W I;  1N8Y C;  4C9A B;  4CDK E;  4BSO A;  4BSS C;  1S78 A;  3I2T A;  4XST E;  3LTF A;  3MZW A;  4P59 A;  4HRN C;  3B2V A;  1MOX A;  4QXF C;  4C9V B;  4C8V A;  4C9R B;  1N8Z C;  1M6B A;  5J3H E;  3NJP A;  3U9U E;  1IGR A;  4C9U B;  3WLW A;  4KNG M;  4C99 B; 
#chains in the Genus database with same CATH topology
 4LEO C;  3U7U A;  2AHX A;  4KRO A;  4BSP A;  4XSS E;  3W11 E;  4BSR C;  3P11 A;  3LTG A;  4LI2 B;  1YY9 A;  4C9E B;  2HR7 A;  3WSQ A;  3QWQ A;  3U2P A;  1IVO A;  2A91 A;  4KT1 E;  3BE1 A;  1NQL A;  4KRP A;  3N85 A;  4UFR B;  4UV7 A;  4OGA E;  4BSU C;  4C8W I;  1N8Y C;  4C9A B;  4CDK E;  4BSO A;  4BSS C;  1S78 A;  3I2T A;  4XST E;  3LTF A;  3MZW A;  4P59 A;  4HRN C;  3B2V A;  1MOX A;  4QXF C;  4C9V B;  4C8V A;  4C9R B;  1N8Z C;  1M6B A;  5J3H E;  3NJP A;  3U9U E;  1IGR A;  4C9U B;  3WLW A;  4KNG M;  4C99 B; 
#chains in the Genus database with same CATH homology
 4LEO C;  3U7U A;  2AHX A;  4KRO A;  4BSP A;  4XSS E;  3W11 E;  4BSR C;  3P11 A;  3LTG A;  4LI2 B;  1YY9 A;  4C9E B;  2HR7 A;  3WSQ A;  3QWQ A;  3U2P A;  1IVO A;  2A91 A;  4KT1 E;  3BE1 A;  1NQL A;  4KRP A;  3N85 A;  4UFR B;  4UV7 A;  4OGA E;  4BSU C;  4C8W I;  1N8Y C;  4C9A B;  4CDK E;  4BSO A;  4BSS C;  1S78 A;  3I2T A;  4XST E;  3LTF A;  3MZW A;  4P59 A;  4HRN C;  3B2V A;  1MOX A;  4QXF C;  4C9V B;  4C8V A;  4C9R B;  1N8Z C;  1M6B A;  5J3H E;  3NJP A;  3U9U E;  1IGR A;  4C9U B;  3WLW A;  4KNG M;  4C99 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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