4C99B

Mouse znrf3 ectodomain in complex with mouse rspo2 fu1-fu2 crystal form i
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
103
structure length
103
Chain Sequence
ICKGCLSCSKDNGCSRCQQKLFFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLDETMEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
pubmed doi rcsb
molecule tags Ligase/signaling protein
source organism Mus musculus
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE ZNRF3
total genus 16
structure length 103
sequence length 103
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-10-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4c99B00
3U7UA 3P11A 4UFRB 1N8YC 4LEOC 4QXFC 1M6BA 4C9RB 4C99B 1YY9A 1MOXA 3U9UE 3N85A 3QWQA 3W11E 3WSQA 4C9VB 4BSRC 3LTGA 4KT1E 4UV7A 1N8ZC 3NJPA 4XSTE 3WLWA 4C9AB 4C9UB 1S78A 4KNGM 1NQLA 1IVOA 5J3HE 4CDKE 4LI2B 4P59A 1IGRA 4KRPA 4BSPA 3LTFA 4KROA 4C8WI 3MZWA 4BSSC 4HRNC 3BE1A 2HR7A 3B2VA 4OGAE 4BSOA 4BSUC 4C8VA 4C9EB 3I2TA 3U2PA 4XSSE 2A91A 2AHXA
chains in the Genus database with same CATH superfamily
3U7UA 3P11A 4UFRB 1N8YC 4LEOC 4QXFC 1M6BA 4C9RB 4C99B 1YY9A 1MOXA 3U9UE 3N85A 3QWQA 3W11E 3WSQA 4C9VB 4BSRC 3LTGA 4KT1E 4UV7A 1N8ZC 3NJPA 4XSTE 3WLWA 4C9AB 4C9UB 1S78A 4KNGM 1NQLA 1IVOA 5J3HE 4CDKE 4LI2B 4P59A 1IGRA 4KRPA 4BSPA 3LTFA 4KROA 4C8WI 3MZWA 4BSSC 4HRNC 3BE1A 2HR7A 3B2VA 4OGAE 4BSOA 4BSUC 4C8VA 4C9EB 3I2TA 3U2PA 4XSSE 2A91A 2AHXA
chains in the Genus database with same CATH topology
3U7UA 3P11A 4UFRB 1N8YC 4LEOC 4QXFC 1M6BA 4C9RB 4C99B 1YY9A 1MOXA 3U9UE 3N85A 3QWQA 3W11E 3WSQA 4C9VB 4BSRC 3LTGA 4KT1E 4UV7A 1N8ZC 3NJPA 4XSTE 3WLWA 4C9AB 4C9UB 1S78A 4KNGM 1NQLA 1IVOA 5J3HE 4CDKE 4LI2B 4P59A 1IGRA 4KRPA 4BSPA 3LTFA 4KROA 4C8WI 3MZWA 4BSSC 4HRNC 3BE1A 2HR7A 3B2VA 4OGAE 4BSOA 4BSUC 4C8VA 4C9EB 3I2TA 3U2PA 4XSSE 2A91A 2AHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U7U A;  3P11 A;  4UFR B;  1N8Y C;  4LEO C;  4QXF C;  1M6B A;  4C9R B;  4C99 B;  1YY9 A;  1MOX A;  3U9U E;  3N85 A;  3QWQ A;  3W11 E;  3WSQ A;  4C9V B;  4BSR C;  3LTG A;  4KT1 E;  4UV7 A;  1N8Z C;  3NJP A;  4XST E;  3WLW A;  4C9A B;  4C9U B;  1S78 A;  4KNG M;  1NQL A;  1IVO A;  5J3H E;  4CDK E;  4LI2 B;  4P59 A;  1IGR A;  4KRP A;  4BSP A;  3LTF A;  4KRO A;  4C8W I;  3MZW A;  4BSS C;  4HRN C;  3BE1 A;  2HR7 A;  3B2V A;  4OGA E;  4BSO A;  4BSU C;  4C8V A;  4C9E B;  3I2T A;  3U2P A;  4XSS E;  2A91 A;  2AHX A; 
#chains in the Genus database with same CATH topology
 3U7U A;  3P11 A;  4UFR B;  1N8Y C;  4LEO C;  4QXF C;  1M6B A;  4C9R B;  4C99 B;  1YY9 A;  1MOX A;  3U9U E;  3N85 A;  3QWQ A;  3W11 E;  3WSQ A;  4C9V B;  4BSR C;  3LTG A;  4KT1 E;  4UV7 A;  1N8Z C;  3NJP A;  4XST E;  3WLW A;  4C9A B;  4C9U B;  1S78 A;  4KNG M;  1NQL A;  1IVO A;  5J3H E;  4CDK E;  4LI2 B;  4P59 A;  1IGR A;  4KRP A;  4BSP A;  3LTF A;  4KRO A;  4C8W I;  3MZW A;  4BSS C;  4HRN C;  3BE1 A;  2HR7 A;  3B2V A;  4OGA E;  4BSO A;  4BSU C;  4C8V A;  4C9E B;  3I2T A;  3U2P A;  4XSS E;  2A91 A;  2AHX A; 
#chains in the Genus database with same CATH homology
 3U7U A;  3P11 A;  4UFR B;  1N8Y C;  4LEO C;  4QXF C;  1M6B A;  4C9R B;  4C99 B;  1YY9 A;  1MOX A;  3U9U E;  3N85 A;  3QWQ A;  3W11 E;  3WSQ A;  4C9V B;  4BSR C;  3LTG A;  4KT1 E;  4UV7 A;  1N8Z C;  3NJP A;  4XST E;  3WLW A;  4C9A B;  4C9U B;  1S78 A;  4KNG M;  1NQL A;  1IVO A;  5J3H E;  4CDK E;  4LI2 B;  4P59 A;  1IGR A;  4KRP A;  4BSP A;  3LTF A;  4KRO A;  4C8W I;  3MZW A;  4BSS C;  4HRN C;  3BE1 A;  2HR7 A;  3B2V A;  4OGA E;  4BSO A;  4BSU C;  4C8V A;  4C9E B;  3I2T A;  3U2P A;  4XSS E;  2A91 A;  2AHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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