4CN2C

Crystal structure of the human retinoid x receptor dna-binding domain bound to the human ramp2 response element
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
82
structure length
82
Chain Sequence
MFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*TP*GP*AP*GP*TP*TP*CP*AP*AP*GP*GP*GP*TP*DC *AP*AP*TP)-3
total genus 16
structure length 82
sequence length 82
chains with identical sequence D
ec nomenclature
pdb deposition date 2014-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 4cn2C00
5GATA 3G99A 3G97A 5L0MA 2HANB 1HCQA 1HLZA 5EMPA 5CBXA 1GDCA 1LV3A 3E00D 3G8UA 2EBLA 3G9OA 1R0OB 4NQAB 5CC0A 4HN5A 4HN6A 2GATA 1CITA 4CN3D 2VUUI 2NLLB 1HCPA 3G8XA 3DZYA 4TMAI 1YNWB 4TNTA 4ONDA 5E6CA 4AA6A 1KB2A 3G9PA 4CN7A 1KB6A 2C7AA 3DFVC 3CBBA 4CN5A 5E6AA 1DSZB 1R4IA 3DZUD 3VD6C 1R4RA 3M9EA 1GATA 3G9MA 1LO1A 1RGDA 1GLUA 3G6PA 3DFXA 1RXRA 5KRBB 3G6RA 5E6BA 4IQRA 5CC1A 5CBZA 4OORA 5CBYA 2VUSI 4OV7A 7GATA 1R0NA 3E00A 1GA5A 4HC9A 1R4OA 6GATA 2M9WA 4CN3A 2A66A 3GATA 2ENVA 4CN2C 2FF0A 4OLNA 4HC7A 1GAUA 5E69A 3DZYD 5EMQA 2KAEA 2HANA 1KB4A 2GDAA 3G9IA 5E6DA 3VEKC 2VUTI 1HRAA 5EMCA 1LATA 3G6TA 1R0OA 1DSZA 1R0NB 3DZUA 3G6UA 2NLLA 3G9JA 1BY4A 1A6YA 3G6QA 1GNFA 4GATA 1YNWA 3FYLA 4HCAA
chains in the Genus database with same CATH superfamily
5GATA 3G27A 3G99A 3G97A 5L0MA 2HANB 2DS8A 1HCQA 1HLZA 5EMPA 5CBXA 1GDCA 1LV3A 3E00D 3G8UA 2EBLA 3G9OA 1R0OB 4NQAB 5CC0A 4HN5A 4HN6A 2GATA 1CITA 4CN3D 2VUUI 2NLLB 1HCPA 3G8XA 3DZYA 4TMAI 1YNWB 4TNTA 4ONDA 5E6CA 4AA6A 1KB2A 3G9PA 4CN7A 1KB6A 2C7AA 3DFVC 3CBBA 4CN5A 5E6AA 1DSZB 1R4IA 3DZUD 3VD6C 1R4RA 3M9EA 1GATA 3G9MA 1LO1A 1RGDA 1GLUA 3G6PA 3DFXA 1RXRA 5KRBB 3G6RA 5E6BA 4IQRA 5CC1A 5CBZA 4OORA 5CBYA 2VUSI 4OV7A 7GATA 1R0NA 3E00A 1GA5A 4HC9A 1R4OA 6GATA 2M9WA 4CN3A 2A66A 3GATA 2ENVA 4CN2C 2FF0A 4OLNA 4HC7A 1GAUA 5E69A 2DS6A 3DZYD 5EMQA 2KAEA 2HANA 1KB4A 2GDAA 3G9IA 5E6DA 3VEKC 2VUTI 1HRAA 5EMCA 1LATA 3G6TA 1R0OA 1DSZA 1R0NB 3DZUA 3G6UA 2NLLA 3G9JA 1BY4A 1A6YA 3G6QA 1GNFA 4GATA 2DS5A 1YNWA 3FYLA 4HCAA
chains in the Genus database with same CATH topology
5GATA 3G99A 3G97A 5L0MA 2HANB 1HCQA 1HLZA 5EMPA 5CBXA 1GDCA 1LV3A 3E00D 3G8UA 2EBLA 3G9OA 1R0OB 4NQAB 5CC0A 4HN5A 4HN6A 2GATA 1CITA 4CN3D 2VUUI 2NLLB 1HCPA 3G8XA 3DZYA 4TMAI 1YNWB 4TNTA 4ONDA 5E6CA 4AA6A 1KB2A 3G9PA 4CN7A 1KB6A 2C7AA 3DFVC 3CBBA 4CN5A 5E6AA 1DSZB 1R4IA 3DZUD 3VD6C 1R4RA 3M9EA 1GATA 3G9MA 1LO1A 1RGDA 1GLUA 3G6PA 3DFXA 1RXRA 5KRBB 3G6RA 5E6BA 4IQRA 5CC1A 5CBZA 4OORA 5CBYA 2VUSI 4OV7A 7GATA 1R0NA 3E00A 1GA5A 4HC9A 1R4OA 6GATA 2M9WA 4CN3A 2A66A 3GATA 2ENVA 4CN2C 2FF0A 4OLNA 4HC7A 1GAUA 5E69A 3DZYD 5EMQA 2KAEA 2HANA 1KB4A 2GDAA 3G9IA 5E6DA 3VEKC 2VUTI 1HRAA 5EMCA 1LATA 3G6TA 1R0OA 1DSZA 1R0NB 3DZUA 3G6UA 2NLLA 3G9JA 1BY4A 1A6YA 3G6QA 1GNFA 4GATA 1YNWA 3FYLA 4HCAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAT A;  3G99 A;  3G97 A;  5L0M A;  2HAN B;  1HCQ A;  1HLZ A;  5EMP A;  5CBX A;  1GDC A;  1LV3 A;  3E00 D;  3G8U A;  2EBL A;  3G9O A;  1R0O B;  4NQA B;  5CC0 A;  4HN5 A;  4HN6 A;  2GAT A;  1CIT A;  4CN3 D;  2VUU I;  2NLL B;  1HCP A;  3G8X A;  3DZY A;  4TMA I;  1YNW B;  4TNT A;  4OND A;  5E6C A;  4AA6 A;  1KB2 A;  3G9P A;  4CN7 A;  1KB6 A;  2C7A A;  3DFV C;  3CBB A;  4CN5 A;  5E6A A;  1DSZ B;  1R4I A;  3DZU D;  3VD6 C;  1R4R A;  3M9E A;  1GAT A;  3G9M A;  1LO1 A;  1RGD A;  1GLU A;  3G6P A;  3DFX A;  1RXR A;  5KRB B;  3G6R A;  5E6B A;  4IQR A;  5CC1 A;  5CBZ A;  4OOR A;  5CBY A;  2VUS I;  4OV7 A;  7GAT A;  1R0N A;  3E00 A;  1GA5 A;  4HC9 A;  1R4O A;  6GAT A;  2M9W A;  4CN3 A;  2A66 A;  3GAT A;  2ENV A;  4CN2 C;  2FF0 A;  4OLN A;  4HC7 A;  1GAU A;  5E69 A;  3DZY D;  5EMQ A;  2KAE A;  2HAN A;  1KB4 A;  2GDA A;  3G9I A;  5E6D A;  3VEK C;  2VUT I;  1HRA A;  5EMC A;  1LAT A;  3G6T A;  1R0O A;  1DSZ A;  1R0N B;  3DZU A;  3G6U A;  2NLL A;  3G9J A;  1BY4 A;  1A6Y A;  3G6Q A;  1GNF A;  4GAT A;  1YNW A;  3FYL A;  4HCA A; 
#chains in the Genus database with same CATH topology
 5GAT A;  3G27 A;  3G99 A;  3G97 A;  5L0M A;  2HAN B;  2DS8 A;  1HCQ A;  1HLZ A;  5EMP A;  5CBX A;  1GDC A;  1LV3 A;  3E00 D;  3G8U A;  2EBL A;  3G9O A;  1R0O B;  4NQA B;  5CC0 A;  4HN5 A;  4HN6 A;  2GAT A;  1CIT A;  4CN3 D;  2VUU I;  2NLL B;  1HCP A;  3G8X A;  3DZY A;  4TMA I;  1YNW B;  4TNT A;  4OND A;  5E6C A;  4AA6 A;  1KB2 A;  3G9P A;  4CN7 A;  1KB6 A;  2C7A A;  3DFV C;  3CBB A;  4CN5 A;  5E6A A;  1DSZ B;  1R4I A;  3DZU D;  3VD6 C;  1R4R A;  3M9E A;  1GAT A;  3G9M A;  1LO1 A;  1RGD A;  1GLU A;  3G6P A;  3DFX A;  1RXR A;  5KRB B;  3G6R A;  5E6B A;  4IQR A;  5CC1 A;  5CBZ A;  4OOR A;  5CBY A;  2VUS I;  4OV7 A;  7GAT A;  1R0N A;  3E00 A;  1GA5 A;  4HC9 A;  1R4O A;  6GAT A;  2M9W A;  4CN3 A;  2A66 A;  3GAT A;  2ENV A;  4CN2 C;  2FF0 A;  4OLN A;  4HC7 A;  1GAU A;  5E69 A;  2DS6 A;  3DZY D;  5EMQ A;  2KAE A;  2HAN A;  1KB4 A;  2GDA A;  3G9I A;  5E6D A;  3VEK C;  2VUT I;  1HRA A;  5EMC A;  1LAT A;  3G6T A;  1R0O A;  1DSZ A;  1R0N B;  3DZU A;  3G6U A;  2NLL A;  3G9J A;  1BY4 A;  1A6Y A;  3G6Q A;  1GNF A;  4GAT A;  2DS5 A;  1YNW A;  3FYL A;  4HCA A; 
#chains in the Genus database with same CATH homology
 5GAT A;  3G99 A;  3G97 A;  5L0M A;  2HAN B;  1HCQ A;  1HLZ A;  5EMP A;  5CBX A;  1GDC A;  1LV3 A;  3E00 D;  3G8U A;  2EBL A;  3G9O A;  1R0O B;  4NQA B;  5CC0 A;  4HN5 A;  4HN6 A;  2GAT A;  1CIT A;  4CN3 D;  2VUU I;  2NLL B;  1HCP A;  3G8X A;  3DZY A;  4TMA I;  1YNW B;  4TNT A;  4OND A;  5E6C A;  4AA6 A;  1KB2 A;  3G9P A;  4CN7 A;  1KB6 A;  2C7A A;  3DFV C;  3CBB A;  4CN5 A;  5E6A A;  1DSZ B;  1R4I A;  3DZU D;  3VD6 C;  1R4R A;  3M9E A;  1GAT A;  3G9M A;  1LO1 A;  1RGD A;  1GLU A;  3G6P A;  3DFX A;  1RXR A;  5KRB B;  3G6R A;  5E6B A;  4IQR A;  5CC1 A;  5CBZ A;  4OOR A;  5CBY A;  2VUS I;  4OV7 A;  7GAT A;  1R0N A;  3E00 A;  1GA5 A;  4HC9 A;  1R4O A;  6GAT A;  2M9W A;  4CN3 A;  2A66 A;  3GAT A;  2ENV A;  4CN2 C;  2FF0 A;  4OLN A;  4HC7 A;  1GAU A;  5E69 A;  3DZY D;  5EMQ A;  2KAE A;  2HAN A;  1KB4 A;  2GDA A;  3G9I A;  5E6D A;  3VEK C;  2VUT I;  1HRA A;  5EMC A;  1LAT A;  3G6T A;  1R0O A;  1DSZ A;  1R0N B;  3DZU A;  3G6U A;  2NLL A;  3G9J A;  1BY4 A;  1A6Y A;  3G6Q A;  1GNF A;  4GAT A;  1YNW A;  3FYL A;  4HCA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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