4CN5A

Crystal structure of the human retinoid x receptor dna-binding domain bound to the human nr1d1 response element
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
81
structure length
81
Chain Sequence
MFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords RETINOIC ACID RECEPTOR RXR-ALPHA
total genus 17
structure length 81
sequence length 81
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00105 zf-C4 Zinc finger, C4 type (two domains)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 4cn5A00
2EBLA 5CC1A 1R4OA 5CC0A 1HLZA 3DZUD 4OLNA 4TNTA 2VUSI 1GAUA 3M9EA 3E00D 4OV7A 5CBYA 3G9OA 5E6DA 1KB2A 4OORA 1YNWA 3G6TA 3FYLA 2GDAA 1LO1A 1LV3A 2NLLA 2GATA 6GATA 1HCPA 1CITA 5EMCA 5CBZA 2NLLB 3G9JA 5EMPA 4TMAI 5EMQA 1GLUA 2KAEA 1R0OA 3G99A 1GNFA 3G6PA 1RGDA 1HCQA 5E69A 4HC9A 3G6UA 3G9MA 1KB6A 2FF0A 3CBBA 2M9WA 4HC7A 3DZUA 7GATA 1YNWB 3DZYD 4NQAB 3E00A 3GATA 4CN3D 5E6AA 3VD6C 1A6YA 4HCAA 5CBXA 1HRAA 5KRBB 1R0NA 1RXRA 3G9IA 3G8XA 3DFVC 4HN6A 3G97A 1GDCA 5E6CA 3VEKC 2ENVA 1R0NB 2VUUI 3G6RA 1R0OB 2VUTI 1DSZA 4ONDA 4IQRA 3DFXA 1KB4A 4CN7A 1GA5A 2HANA 1BY4A 1DSZB 2A66A 1R4IA 1GATA 2HANB 4HN5A 5L0MA 5E6BA 3G8UA 3DZYA 5GATA 4CN2C 4GATA 4CN3A 2C7AA 3G6QA 1R4RA 4AA6A 1LATA 3G9PA 4CN5A
chains in the Genus database with same CATH superfamily
2EBLA 5CC1A 1R4OA 5CC0A 1HLZA 3DZUD 4OLNA 4TNTA 2VUSI 1GAUA 3M9EA 3E00D 4OV7A 5CBYA 3G9OA 5E6DA 1KB2A 4OORA 1YNWA 3G6TA 3FYLA 2GDAA 2DS6A 1LO1A 1LV3A 2NLLA 2GATA 6GATA 1HCPA 1CITA 3G27A 5EMCA 5CBZA 2NLLB 3G9JA 5EMPA 4TMAI 5EMQA 1GLUA 2KAEA 1R0OA 3G99A 1GNFA 3G6PA 1RGDA 1HCQA 5E69A 4HC9A 3G6UA 3G9MA 1KB6A 2FF0A 3CBBA 2M9WA 4HC7A 3DZUA 7GATA 1YNWB 3DZYD 4NQAB 3E00A 3GATA 4CN3D 5E6AA 3VD6C 1A6YA 4HCAA 5CBXA 1HRAA 5KRBB 1R0NA 1RXRA 3G9IA 3G8XA 3DFVC 4HN6A 3G97A 2DS5A 1GDCA 5E6CA 3VEKC 2ENVA 1R0NB 2VUUI 3G6RA 1R0OB 2VUTI 1DSZA 4ONDA 4IQRA 3DFXA 1KB4A 4CN7A 1GA5A 2HANA 1BY4A 1DSZB 2A66A 1R4IA 1GATA 2DS8A 2HANB 4HN5A 5L0MA 5E6BA 3G8UA 3DZYA 5GATA 4CN2C 4GATA 4CN3A 2C7AA 3G6QA 1R4RA 4AA6A 1LATA 3G9PA 4CN5A
chains in the Genus database with same CATH topology
2EBLA 5CC1A 1R4OA 5CC0A 1HLZA 3DZUD 4OLNA 4TNTA 2VUSI 1GAUA 3M9EA 3E00D 4OV7A 5CBYA 3G9OA 5E6DA 1KB2A 4OORA 1YNWA 3G6TA 3FYLA 2GDAA 1LO1A 1LV3A 2NLLA 2GATA 6GATA 1HCPA 1CITA 5EMCA 5CBZA 2NLLB 3G9JA 5EMPA 4TMAI 5EMQA 1GLUA 2KAEA 1R0OA 3G99A 1GNFA 3G6PA 1RGDA 1HCQA 5E69A 4HC9A 3G6UA 3G9MA 1KB6A 2FF0A 3CBBA 2M9WA 4HC7A 3DZUA 7GATA 1YNWB 3DZYD 4NQAB 3E00A 3GATA 4CN3D 5E6AA 3VD6C 1A6YA 4HCAA 5CBXA 1HRAA 5KRBB 1R0NA 1RXRA 3G9IA 3G8XA 3DFVC 4HN6A 3G97A 1GDCA 5E6CA 3VEKC 2ENVA 1R0NB 2VUUI 3G6RA 1R0OB 2VUTI 1DSZA 4ONDA 4IQRA 3DFXA 1KB4A 4CN7A 1GA5A 2HANA 1BY4A 1DSZB 2A66A 1R4IA 1GATA 2HANB 4HN5A 5L0MA 5E6BA 3G8UA 3DZYA 5GATA 4CN2C 4GATA 4CN3A 2C7AA 3G6QA 1R4RA 4AA6A 1LATA 3G9PA 4CN5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EBL A;  5CC1 A;  1R4O A;  5CC0 A;  1HLZ A;  3DZU D;  4OLN A;  4TNT A;  2VUS I;  1GAU A;  3M9E A;  3E00 D;  4OV7 A;  5CBY A;  3G9O A;  5E6D A;  1KB2 A;  4OOR A;  1YNW A;  3G6T A;  3FYL A;  2GDA A;  1LO1 A;  1LV3 A;  2NLL A;  2GAT A;  6GAT A;  1HCP A;  1CIT A;  5EMC A;  5CBZ A;  2NLL B;  3G9J A;  5EMP A;  4TMA I;  5EMQ A;  1GLU A;  2KAE A;  1R0O A;  3G99 A;  1GNF A;  3G6P A;  1RGD A;  1HCQ A;  5E69 A;  4HC9 A;  3G6U A;  3G9M A;  1KB6 A;  2FF0 A;  3CBB A;  2M9W A;  4HC7 A;  3DZU A;  7GAT A;  1YNW B;  3DZY D;  4NQA B;  3E00 A;  3GAT A;  4CN3 D;  5E6A A;  3VD6 C;  1A6Y A;  4HCA A;  5CBX A;  1HRA A;  5KRB B;  1R0N A;  1RXR A;  3G9I A;  3G8X A;  3DFV C;  4HN6 A;  3G97 A;  1GDC A;  5E6C A;  3VEK C;  2ENV A;  1R0N B;  2VUU I;  3G6R A;  1R0O B;  2VUT I;  1DSZ A;  4OND A;  4IQR A;  3DFX A;  1KB4 A;  4CN7 A;  1GA5 A;  2HAN A;  1BY4 A;  1DSZ B;  2A66 A;  1R4I A;  1GAT A;  2HAN B;  4HN5 A;  5L0M A;  5E6B A;  3G8U A;  3DZY A;  5GAT A;  4CN2 C;  4GAT A;  4CN3 A;  2C7A A;  3G6Q A;  1R4R A;  4AA6 A;  1LAT A;  3G9P A;  4CN5 A; 
#chains in the Genus database with same CATH topology
 2EBL A;  5CC1 A;  1R4O A;  5CC0 A;  1HLZ A;  3DZU D;  4OLN A;  4TNT A;  2VUS I;  1GAU A;  3M9E A;  3E00 D;  4OV7 A;  5CBY A;  3G9O A;  5E6D A;  1KB2 A;  4OOR A;  1YNW A;  3G6T A;  3FYL A;  2GDA A;  2DS6 A;  1LO1 A;  1LV3 A;  2NLL A;  2GAT A;  6GAT A;  1HCP A;  1CIT A;  3G27 A;  5EMC A;  5CBZ A;  2NLL B;  3G9J A;  5EMP A;  4TMA I;  5EMQ A;  1GLU A;  2KAE A;  1R0O A;  3G99 A;  1GNF A;  3G6P A;  1RGD A;  1HCQ A;  5E69 A;  4HC9 A;  3G6U A;  3G9M A;  1KB6 A;  2FF0 A;  3CBB A;  2M9W A;  4HC7 A;  3DZU A;  7GAT A;  1YNW B;  3DZY D;  4NQA B;  3E00 A;  3GAT A;  4CN3 D;  5E6A A;  3VD6 C;  1A6Y A;  4HCA A;  5CBX A;  1HRA A;  5KRB B;  1R0N A;  1RXR A;  3G9I A;  3G8X A;  3DFV C;  4HN6 A;  3G97 A;  2DS5 A;  1GDC A;  5E6C A;  3VEK C;  2ENV A;  1R0N B;  2VUU I;  3G6R A;  1R0O B;  2VUT I;  1DSZ A;  4OND A;  4IQR A;  3DFX A;  1KB4 A;  4CN7 A;  1GA5 A;  2HAN A;  1BY4 A;  1DSZ B;  2A66 A;  1R4I A;  1GAT A;  2DS8 A;  2HAN B;  4HN5 A;  5L0M A;  5E6B A;  3G8U A;  3DZY A;  5GAT A;  4CN2 C;  4GAT A;  4CN3 A;  2C7A A;  3G6Q A;  1R4R A;  4AA6 A;  1LAT A;  3G9P A;  4CN5 A; 
#chains in the Genus database with same CATH homology
 2EBL A;  5CC1 A;  1R4O A;  5CC0 A;  1HLZ A;  3DZU D;  4OLN A;  4TNT A;  2VUS I;  1GAU A;  3M9E A;  3E00 D;  4OV7 A;  5CBY A;  3G9O A;  5E6D A;  1KB2 A;  4OOR A;  1YNW A;  3G6T A;  3FYL A;  2GDA A;  1LO1 A;  1LV3 A;  2NLL A;  2GAT A;  6GAT A;  1HCP A;  1CIT A;  5EMC A;  5CBZ A;  2NLL B;  3G9J A;  5EMP A;  4TMA I;  5EMQ A;  1GLU A;  2KAE A;  1R0O A;  3G99 A;  1GNF A;  3G6P A;  1RGD A;  1HCQ A;  5E69 A;  4HC9 A;  3G6U A;  3G9M A;  1KB6 A;  2FF0 A;  3CBB A;  2M9W A;  4HC7 A;  3DZU A;  7GAT A;  1YNW B;  3DZY D;  4NQA B;  3E00 A;  3GAT A;  4CN3 D;  5E6A A;  3VD6 C;  1A6Y A;  4HCA A;  5CBX A;  1HRA A;  5KRB B;  1R0N A;  1RXR A;  3G9I A;  3G8X A;  3DFV C;  4HN6 A;  3G97 A;  1GDC A;  5E6C A;  3VEK C;  2ENV A;  1R0N B;  2VUU I;  3G6R A;  1R0O B;  2VUT I;  1DSZ A;  4OND A;  4IQR A;  3DFX A;  1KB4 A;  4CN7 A;  1GA5 A;  2HAN A;  1BY4 A;  1DSZ B;  2A66 A;  1R4I A;  1GAT A;  2HAN B;  4HN5 A;  5L0M A;  5E6B A;  3G8U A;  3DZY A;  5GAT A;  4CN2 C;  4GAT A;  4CN3 A;  2C7A A;  3G6Q A;  1R4R A;  4AA6 A;  1LAT A;  3G9P A;  4CN5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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