4KNGM

Crystal structure of human lgr5-rspo1-rnf43
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
104
structure length
98
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGTMECS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein, membrane protein
source organism Homo sapiens
publication title The structural basis of R-spondin recognition by LGR5 and RNF43.
pubmed doi rcsb
molecule keywords Leucine-rich repeat-containing G-protein coupled receptor 5
total genus 17
structure length 98
sequence length 104
chains with identical sequence P
ec nomenclature
pdb deposition date 2013-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4kngM00
1NQLA 2HR7A 4KRPA 4BSRC 1N8YC 3LTGA 4QXFC 3I2TA 5J3HE 3B2VA 4OGAE 4HRNC 3U9UE 3BE1A 3LTFA 1N8ZC 2AHXA 4LI2B 4BSPA 4C8WI 3N85A 4XSSE 4BSSC 4C9EB 4BSOA 4C9AB 4XSTE 3MZWA 1MOXA 3QWQA 4UV7A 3U7UA 3P11A 4C8VA 4P59A 4C9VB 4C9UB 4KNGM 3WLWA 4C9RB 2A91A 1IGRA 3W11E 4KROA 4KT1E 4UFRB 1S78A 3NJPA 4LEOC 3U2PA 1YY9A 4BSUC 4C99B 1M6BA 1IVOA 3WSQA 4CDKE
chains in the Genus database with same CATH superfamily
1NQLA 2HR7A 4KRPA 4BSRC 1N8YC 3LTGA 4QXFC 3I2TA 5J3HE 3B2VA 4OGAE 4HRNC 3U9UE 3BE1A 3LTFA 1N8ZC 2AHXA 4LI2B 4BSPA 4C8WI 3N85A 4XSSE 4BSSC 4C9EB 4BSOA 4C9AB 4XSTE 3MZWA 1MOXA 3QWQA 4UV7A 3U7UA 3P11A 4C8VA 4P59A 4C9VB 4C9UB 4KNGM 3WLWA 4C9RB 2A91A 1IGRA 3W11E 4KROA 4KT1E 4UFRB 1S78A 3NJPA 4LEOC 3U2PA 1YY9A 4BSUC 4C99B 1M6BA 1IVOA 3WSQA 4CDKE
chains in the Genus database with same CATH topology
1NQLA 2HR7A 4KRPA 4BSRC 1N8YC 3LTGA 4QXFC 3I2TA 5J3HE 3B2VA 4OGAE 4HRNC 3U9UE 3BE1A 3LTFA 1N8ZC 2AHXA 4LI2B 4BSPA 4C8WI 3N85A 4XSSE 4BSSC 4C9EB 4BSOA 4C9AB 4XSTE 3MZWA 1MOXA 3QWQA 4UV7A 3U7UA 3P11A 4C8VA 4P59A 4C9VB 4C9UB 4KNGM 3WLWA 4C9RB 2A91A 1IGRA 3W11E 4KROA 4KT1E 4UFRB 1S78A 3NJPA 4LEOC 3U2PA 1YY9A 4BSUC 4C99B 1M6BA 1IVOA 3WSQA 4CDKE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NQL A;  2HR7 A;  4KRP A;  4BSR C;  1N8Y C;  3LTG A;  4QXF C;  3I2T A;  5J3H E;  3B2V A;  4OGA E;  4HRN C;  3U9U E;  3BE1 A;  3LTF A;  1N8Z C;  2AHX A;  4LI2 B;  4BSP A;  4C8W I;  3N85 A;  4XSS E;  4BSS C;  4C9E B;  4BSO A;  4C9A B;  4XST E;  3MZW A;  1MOX A;  3QWQ A;  4UV7 A;  3U7U A;  3P11 A;  4C8V A;  4P59 A;  4C9V B;  4C9U B;  4KNG M;  3WLW A;  4C9R B;  2A91 A;  1IGR A;  3W11 E;  4KRO A;  4KT1 E;  4UFR B;  1S78 A;  3NJP A;  4LEO C;  3U2P A;  1YY9 A;  4BSU C;  4C99 B;  1M6B A;  1IVO A;  3WSQ A;  4CDK E; 
#chains in the Genus database with same CATH topology
 1NQL A;  2HR7 A;  4KRP A;  4BSR C;  1N8Y C;  3LTG A;  4QXF C;  3I2T A;  5J3H E;  3B2V A;  4OGA E;  4HRN C;  3U9U E;  3BE1 A;  3LTF A;  1N8Z C;  2AHX A;  4LI2 B;  4BSP A;  4C8W I;  3N85 A;  4XSS E;  4BSS C;  4C9E B;  4BSO A;  4C9A B;  4XST E;  3MZW A;  1MOX A;  3QWQ A;  4UV7 A;  3U7U A;  3P11 A;  4C8V A;  4P59 A;  4C9V B;  4C9U B;  4KNG M;  3WLW A;  4C9R B;  2A91 A;  1IGR A;  3W11 E;  4KRO A;  4KT1 E;  4UFR B;  1S78 A;  3NJP A;  4LEO C;  3U2P A;  1YY9 A;  4BSU C;  4C99 B;  1M6B A;  1IVO A;  3WSQ A;  4CDK E; 
#chains in the Genus database with same CATH homology
 1NQL A;  2HR7 A;  4KRP A;  4BSR C;  1N8Y C;  3LTG A;  4QXF C;  3I2T A;  5J3H E;  3B2V A;  4OGA E;  4HRN C;  3U9U E;  3BE1 A;  3LTF A;  1N8Z C;  2AHX A;  4LI2 B;  4BSP A;  4C8W I;  3N85 A;  4XSS E;  4BSS C;  4C9E B;  4BSO A;  4C9A B;  4XST E;  3MZW A;  1MOX A;  3QWQ A;  4UV7 A;  3U7U A;  3P11 A;  4C8V A;  4P59 A;  4C9V B;  4C9U B;  4KNG M;  3WLW A;  4C9R B;  2A91 A;  1IGR A;  3W11 E;  4KRO A;  4KT1 E;  4UFR B;  1S78 A;  3NJP A;  4LEO C;  3U2P A;  1YY9 A;  4BSU C;  4C99 B;  1M6B A;  1IVO A;  3WSQ A;  4CDK E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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