4N9F0

Crystal structure of the vif-cbfbeta-cul5-elob-eloc pentameric complex
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
153
structure length
144
Chain Sequence
VPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVATGTNLSLQFFPASWREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLDGMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for hijacking CBF-b and CUL5 E3 ligase complex by HIV-1 Vif
rcsb
molecule keywords Cullin-5
molecule tags Ligase/viral protein
source organism Homo sapiens
total genus 27
structure length 144
sequence length 153
chains with identical sequence 6, F, L, N, R, a, c, i, k, o, u
ec nomenclature
pdb deposition date 2013-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
0 PF02312 CBF_beta Core binding factor beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.250.10 Mainly Beta Beta Barrel Polyomavirus Enhancer Binding Protein 2; Chain: A; Core binding factor, beta subunit 4n9f000
3WTXB 3WTYB 3WTVB 2JHBA 1H9DB 3WTUB 3WTSB 1CL3A 3WTTB 1IO4D 1ILFA 4N9F0 3WTWB 1E50B
chains in the Genus database with same CATH superfamily
3WTXB 3WTYB 3WTVB 2JHBA 1H9DB 3WTUB 3WTSB 1CL3A 3WTTB 1IO4D 1ILFA 4N9F0 3WTWB 1E50B
chains in the Genus database with same CATH topology
3WTXB 3WTYB 3WTVB 2JHBA 1H9DB 3WTUB 3WTSB 1CL3A 3WTTB 1IO4D 1ILFA 4N9F0 3WTWB 1E50B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WTX B;  3WTY B;  3WTV B;  2JHB A;  1H9D B;  3WTU B;  3WTS B;  1CL3 A;  3WTT B;  1IO4 D;  1ILF A;  4N9F 0;  3WTW B;  1E50 B; 
#chains in the Genus database with same CATH topology
 3WTX B;  3WTY B;  3WTV B;  2JHB A;  1H9D B;  3WTU B;  3WTS B;  1CL3 A;  3WTT B;  1IO4 D;  1ILF A;  4N9F 0;  3WTW B;  1E50 B; 
#chains in the Genus database with same CATH homology
 3WTX B;  3WTY B;  3WTV B;  2JHB A;  1H9D B;  3WTU B;  3WTS B;  1CL3 A;  3WTT B;  1IO4 D;  1ILF A;  4N9F 0;  3WTW B;  1E50 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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