4OV7A

Ancestral steroid receptor 2 dbd helix mutant - sre dna complex
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
73
structure length
73
Chain Sequence
PQKVCLICGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLRKCLQAGMTLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Synthetic construct
molecule keywords Ancestral Steroid Receptor 2 DBD helix mutant
total genus 15
structure length 73
sequence length 73
chains with identical sequence B, E, F
ec nomenclature
pdb deposition date 2014-02-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.50.10 Alpha Beta 2-Layer Sandwich Erythroid Transcription Factor GATA-1; Chain A Erythroid Transcription Factor GATA-1, subunit A 4ov7A00
1R0NB 1DSZB 4GATA 4CN5A 3CBBA 3G9MA 3VD6C 4HC9A 3DZYA 4IQRA 3M9EA 3DZUA 4CN3A 4HN5A 2EBLA 4HCAA 3DZYD 5E6CA 5EMQA 3G99A 1LV3A 3G8XA 3DZUD 4CN3D 2NLLB 2HANA 1R4RA 5E6BA 1KB6A 4CN7A 3G6PA 1HLZA 1R4OA 5E6DA 1HRAA 1LATA 3DFVC 4HN6A 4HC7A 4TNTA 1GLUA 3G6RA 2HANB 1BY4A 1RGDA 1YNWB 1RXRA 1HCQA 4OV7A 5E69A 1KB4A 3FYLA 4ONDA 3DFXA 3GATA 5CC0A 3G9PA 1A6YA 1HCPA 3G6QA 3G97A 4AA6A 2VUUI 2M9WA 2A66A 5EMCA 3G8UA 2C7AA 3G6UA 5KRBB 3G9JA 1R0OA 1GATA 5E6AA 4OLNA 1GDCA 1CITA 1KB2A 5L0MA 2VUTI 4TMAI 1LO1A 1R4IA 2ENVA 5EMPA 1R0NA 1DSZA 5CBYA 1GAUA 3G9IA 2KAEA 4NQAB 3VEKC 1R0OB 6GATA 5CBZA 1GA5A 2FF0A 4CN2C 1YNWA 5GATA 3E00A 2NLLA 2GDAA 5CBXA 3G6TA 3E00D 3G9OA 1GNFA 4OORA 5CC1A 7GATA 2VUSI 2GATA
chains in the Genus database with same CATH superfamily
1R0NB 1DSZB 4GATA 4CN5A 3CBBA 3G9MA 3VD6C 4HC9A 3DZYA 4IQRA 3M9EA 3DZUA 4CN3A 4HN5A 2EBLA 4HCAA 3DZYD 5E6CA 5EMQA 3G99A 1LV3A 3G8XA 3DZUD 4CN3D 2NLLB 2HANA 1R4RA 5E6BA 1KB6A 4CN7A 3G6PA 1HLZA 1R4OA 5E6DA 1HRAA 1LATA 3DFVC 4HN6A 4HC7A 4TNTA 1GLUA 3G6RA 2HANB 1BY4A 1RGDA 3G27A 1YNWB 1RXRA 1HCQA 4OV7A 5E69A 1KB4A 2DS5A 3FYLA 4ONDA 3DFXA 3GATA 5CC0A 3G9PA 1A6YA 1HCPA 3G6QA 3G97A 4AA6A 2VUUI 2DS8A 2M9WA 2A66A 5EMCA 3G8UA 2C7AA 3G6UA 5KRBB 3G9JA 1R0OA 1GATA 5E6AA 4OLNA 1GDCA 1CITA 1KB2A 2DS6A 5L0MA 2VUTI 4TMAI 1LO1A 1R4IA 2ENVA 5EMPA 1R0NA 1DSZA 5CBYA 1GAUA 3G9IA 2KAEA 4NQAB 3VEKC 1R0OB 6GATA 5CBZA 1GA5A 2FF0A 4CN2C 1YNWA 5GATA 3E00A 2NLLA 2GDAA 5CBXA 3G6TA 3E00D 3G9OA 1GNFA 4OORA 5CC1A 7GATA 2VUSI 2GATA
chains in the Genus database with same CATH topology
1R0NB 1DSZB 4GATA 4CN5A 3CBBA 3G9MA 3VD6C 4HC9A 3DZYA 4IQRA 3M9EA 3DZUA 4CN3A 4HN5A 2EBLA 4HCAA 3DZYD 5E6CA 5EMQA 3G99A 1LV3A 3G8XA 3DZUD 4CN3D 2NLLB 2HANA 1R4RA 5E6BA 1KB6A 4CN7A 3G6PA 1HLZA 1R4OA 5E6DA 1HRAA 1LATA 3DFVC 4HN6A 4HC7A 4TNTA 1GLUA 3G6RA 2HANB 1BY4A 1RGDA 1YNWB 1RXRA 1HCQA 4OV7A 5E69A 1KB4A 3FYLA 4ONDA 3DFXA 3GATA 5CC0A 3G9PA 1A6YA 1HCPA 3G6QA 3G97A 4AA6A 2VUUI 2M9WA 2A66A 5EMCA 3G8UA 2C7AA 3G6UA 5KRBB 3G9JA 1R0OA 1GATA 5E6AA 4OLNA 1GDCA 1CITA 1KB2A 5L0MA 2VUTI 4TMAI 1LO1A 1R4IA 2ENVA 5EMPA 1R0NA 1DSZA 5CBYA 1GAUA 3G9IA 2KAEA 4NQAB 3VEKC 1R0OB 6GATA 5CBZA 1GA5A 2FF0A 4CN2C 1YNWA 5GATA 3E00A 2NLLA 2GDAA 5CBXA 3G6TA 3E00D 3G9OA 1GNFA 4OORA 5CC1A 7GATA 2VUSI 2GATA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R0N B;  1DSZ B;  4GAT A;  4CN5 A;  3CBB A;  3G9M A;  3VD6 C;  4HC9 A;  3DZY A;  4IQR A;  3M9E A;  3DZU A;  4CN3 A;  4HN5 A;  2EBL A;  4HCA A;  3DZY D;  5E6C A;  5EMQ A;  3G99 A;  1LV3 A;  3G8X A;  3DZU D;  4CN3 D;  2NLL B;  2HAN A;  1R4R A;  5E6B A;  1KB6 A;  4CN7 A;  3G6P A;  1HLZ A;  1R4O A;  5E6D A;  1HRA A;  1LAT A;  3DFV C;  4HN6 A;  4HC7 A;  4TNT A;  1GLU A;  3G6R A;  2HAN B;  1BY4 A;  1RGD A;  1YNW B;  1RXR A;  1HCQ A;  4OV7 A;  5E69 A;  1KB4 A;  3FYL A;  4OND A;  3DFX A;  3GAT A;  5CC0 A;  3G9P A;  1A6Y A;  1HCP A;  3G6Q A;  3G97 A;  4AA6 A;  2VUU I;  2M9W A;  2A66 A;  5EMC A;  3G8U A;  2C7A A;  3G6U A;  5KRB B;  3G9J A;  1R0O A;  1GAT A;  5E6A A;  4OLN A;  1GDC A;  1CIT A;  1KB2 A;  5L0M A;  2VUT I;  4TMA I;  1LO1 A;  1R4I A;  2ENV A;  5EMP A;  1R0N A;  1DSZ A;  5CBY A;  1GAU A;  3G9I A;  2KAE A;  4NQA B;  3VEK C;  1R0O B;  6GAT A;  5CBZ A;  1GA5 A;  2FF0 A;  4CN2 C;  1YNW A;  5GAT A;  3E00 A;  2NLL A;  2GDA A;  5CBX A;  3G6T A;  3E00 D;  3G9O A;  1GNF A;  4OOR A;  5CC1 A;  7GAT A;  2VUS I;  2GAT A; 
#chains in the Genus database with same CATH topology
 1R0N B;  1DSZ B;  4GAT A;  4CN5 A;  3CBB A;  3G9M A;  3VD6 C;  4HC9 A;  3DZY A;  4IQR A;  3M9E A;  3DZU A;  4CN3 A;  4HN5 A;  2EBL A;  4HCA A;  3DZY D;  5E6C A;  5EMQ A;  3G99 A;  1LV3 A;  3G8X A;  3DZU D;  4CN3 D;  2NLL B;  2HAN A;  1R4R A;  5E6B A;  1KB6 A;  4CN7 A;  3G6P A;  1HLZ A;  1R4O A;  5E6D A;  1HRA A;  1LAT A;  3DFV C;  4HN6 A;  4HC7 A;  4TNT A;  1GLU A;  3G6R A;  2HAN B;  1BY4 A;  1RGD A;  3G27 A;  1YNW B;  1RXR A;  1HCQ A;  4OV7 A;  5E69 A;  1KB4 A;  2DS5 A;  3FYL A;  4OND A;  3DFX A;  3GAT A;  5CC0 A;  3G9P A;  1A6Y A;  1HCP A;  3G6Q A;  3G97 A;  4AA6 A;  2VUU I;  2DS8 A;  2M9W A;  2A66 A;  5EMC A;  3G8U A;  2C7A A;  3G6U A;  5KRB B;  3G9J A;  1R0O A;  1GAT A;  5E6A A;  4OLN A;  1GDC A;  1CIT A;  1KB2 A;  2DS6 A;  5L0M A;  2VUT I;  4TMA I;  1LO1 A;  1R4I A;  2ENV A;  5EMP A;  1R0N A;  1DSZ A;  5CBY A;  1GAU A;  3G9I A;  2KAE A;  4NQA B;  3VEK C;  1R0O B;  6GAT A;  5CBZ A;  1GA5 A;  2FF0 A;  4CN2 C;  1YNW A;  5GAT A;  3E00 A;  2NLL A;  2GDA A;  5CBX A;  3G6T A;  3E00 D;  3G9O A;  1GNF A;  4OOR A;  5CC1 A;  7GAT A;  2VUS I;  2GAT A; 
#chains in the Genus database with same CATH homology
 1R0N B;  1DSZ B;  4GAT A;  4CN5 A;  3CBB A;  3G9M A;  3VD6 C;  4HC9 A;  3DZY A;  4IQR A;  3M9E A;  3DZU A;  4CN3 A;  4HN5 A;  2EBL A;  4HCA A;  3DZY D;  5E6C A;  5EMQ A;  3G99 A;  1LV3 A;  3G8X A;  3DZU D;  4CN3 D;  2NLL B;  2HAN A;  1R4R A;  5E6B A;  1KB6 A;  4CN7 A;  3G6P A;  1HLZ A;  1R4O A;  5E6D A;  1HRA A;  1LAT A;  3DFV C;  4HN6 A;  4HC7 A;  4TNT A;  1GLU A;  3G6R A;  2HAN B;  1BY4 A;  1RGD A;  1YNW B;  1RXR A;  1HCQ A;  4OV7 A;  5E69 A;  1KB4 A;  3FYL A;  4OND A;  3DFX A;  3GAT A;  5CC0 A;  3G9P A;  1A6Y A;  1HCP A;  3G6Q A;  3G97 A;  4AA6 A;  2VUU I;  2M9W A;  2A66 A;  5EMC A;  3G8U A;  2C7A A;  3G6U A;  5KRB B;  3G9J A;  1R0O A;  1GAT A;  5E6A A;  4OLN A;  1GDC A;  1CIT A;  1KB2 A;  5L0M A;  2VUT I;  4TMA I;  1LO1 A;  1R4I A;  2ENV A;  5EMP A;  1R0N A;  1DSZ A;  5CBY A;  1GAU A;  3G9I A;  2KAE A;  4NQA B;  3VEK C;  1R0O B;  6GAT A;  5CBZ A;  1GA5 A;  2FF0 A;  4CN2 C;  1YNW A;  5GAT A;  3E00 A;  2NLL A;  2GDA A;  5CBX A;  3G6T A;  3E00 D;  3G9O A;  1GNF A;  4OOR A;  5CC1 A;  7GAT A;  2VUS I;  2GAT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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