4TSNA

Crystal structure of frac with poc bound (crystal form ii)
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
178
structure length
178
Chain Sequence
ADVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
pubmed doi rcsb
molecule tags Toxin
source organism Actinia fragacea
molecule keywords Fragaceatoxin C
total genus 49
structure length 178
sequence length 178
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 4tsnA00
2OFCA 4Z2QA 1KD6A 1Y2UA 4TSQA 1TZQA 1Y2WA 3ZWGA 2L38A 4Z2FA 1XI0A 5BPGA 2OFDA 4TSPA 3ZWJA 4Z2SA 1GWYA 3QDXA 1O71A 2L2BA 1O72A 4TSYA 4YLDA 4WDCA 1X99A 3QDYA 3QDWA 3QDSA 1Y2XA 1Y2VA 3QDUA 1Y2TA 4TSNA 2OFEA 3QDTA 4TSLA 2KS4A 3LIMA 3QDVA 4TSOA 3W9PA 3VWIA 1IAZA
chains in the Genus database with same CATH superfamily
2OFCA 4HPQB 4Z2QA 1KD6A 1Y2UA 4TSQA 1TZQA 1Y2WA 3ZWGA 3A57A 2L38A 4WX3A 1XI0A 4Z2FA 2OFDA 5BPGA 4TSPA 3ZWJA 4Z2SA 1GWYA 3QDXA 1O71A 2L2BA 1O72A 4TSYA 5JHFB 4YLDA 4WDCA 1X99A 3QDYA 3QDWA 3QDSA 1Y2XA 1Y2VA 3QDUA 1Y2TA 4TSNA 2OFEA 3QDTA 4TSLA 4OEBA 2KS4A 3LIMA 3QDVA 4TSOA 3W9PA 4P1WB 4WX5A 4JOXA 3VWIA 1IAZA
chains in the Genus database with same CATH topology
2OFCA 4Z2QA 1KD6A 1Y2UA 4TSQA 1TZQA 1Y2WA 3ZWGA 2L38A 4Z2FA 1XI0A 5BPGA 2OFDA 4TSPA 3ZWJA 4Z2SA 1GWYA 3QDXA 1O71A 2L2BA 1O72A 4TSYA 4YLDA 4WDCA 1X99A 3QDYA 3QDWA 3QDSA 1Y2XA 1Y2VA 3QDUA 1Y2TA 4TSNA 2OFEA 3QDTA 4TSLA 2KS4A 3LIMA 3QDVA 4TSOA 3W9PA 3VWIA 1IAZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OFC A;  4Z2Q A;  1KD6 A;  1Y2U A;  4TSQ A;  1TZQ A;  1Y2W A;  3ZWG A;  2L38 A;  4Z2F A;  1XI0 A;  5BPG A;  2OFD A;  4TSP A;  3ZWJ A;  4Z2S A;  1GWY A;  3QDX A;  1O71 A;  2L2B A;  1O72 A;  4TSY A;  4YLD A;  4WDC A;  1X99 A;  3QDY A;  3QDW A;  3QDS A;  1Y2X A;  1Y2V A;  3QDU A;  1Y2T A;  4TSN A;  2OFE A;  3QDT A;  4TSL A;  2KS4 A;  3LIM A;  3QDV A;  4TSO A;  3W9P A;  3VWI A;  1IAZ A; 
#chains in the Genus database with same CATH topology
 2OFC A;  4HPQ B;  4Z2Q A;  1KD6 A;  1Y2U A;  4TSQ A;  1TZQ A;  1Y2W A;  3ZWG A;  3A57 A;  2L38 A;  4WX3 A;  1XI0 A;  4Z2F A;  2OFD A;  5BPG A;  4TSP A;  3ZWJ A;  4Z2S A;  1GWY A;  3QDX A;  1O71 A;  2L2B A;  1O72 A;  4TSY A;  5JHF B;  4YLD A;  4WDC A;  1X99 A;  3QDY A;  3QDW A;  3QDS A;  1Y2X A;  1Y2V A;  3QDU A;  1Y2T A;  4TSN A;  2OFE A;  3QDT A;  4TSL A;  4OEB A;  2KS4 A;  3LIM A;  3QDV A;  4TSO A;  3W9P A;  4P1W B;  4WX5 A;  4JOX A;  3VWI A;  1IAZ A; 
#chains in the Genus database with same CATH homology
 2OFC A;  4Z2Q A;  1KD6 A;  1Y2U A;  4TSQ A;  1TZQ A;  1Y2W A;  3ZWG A;  2L38 A;  4Z2F A;  1XI0 A;  5BPG A;  2OFD A;  4TSP A;  3ZWJ A;  4Z2S A;  1GWY A;  3QDX A;  1O71 A;  2L2B A;  1O72 A;  4TSY A;  4YLD A;  4WDC A;  1X99 A;  3QDY A;  3QDW A;  3QDS A;  1Y2X A;  1Y2V A;  3QDU A;  1Y2T A;  4TSN A;  2OFE A;  3QDT A;  4TSL A;  2KS4 A;  3LIM A;  3QDV A;  4TSO A;  3W9P A;  3VWI A;  1IAZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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