4TSOA

Crystal structure of frac with dhpc bound (crystal form i)
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
177
structure length
177
Chain Sequence
DVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
pubmed doi rcsb
molecule tags Toxin
source organism Actinia fragacea
molecule keywords Fragaceatoxin C
total genus 49
structure length 177
sequence length 177
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 4tsoA00
3LIMA 2OFEA 4TSYA 1IAZA 1Y2WA 3QDSA 4TSOA 3QDVA 4TSQA 3ZWJA 1Y2XA 2L38A 2OFCA 2KS4A 4TSPA 1Y2VA 3VWIA 3QDUA 3QDXA 4YLDA 1O72A 4TSLA 1Y2TA 1KD6A 3W9PA 4WDCA 5BPGA 4TSNA 1Y2UA 1GWYA 1O71A 3QDWA 3ZWGA 4Z2SA 3QDTA 1XI0A 4Z2FA 1TZQA 4Z2QA 3QDYA 1X99A 2OFDA 2L2BA
chains in the Genus database with same CATH superfamily
3LIMA 2OFEA 4TSYA 1IAZA 1Y2WA 3QDSA 4TSOA 3QDVA 4TSQA 4WX5A 3ZWJA 1Y2XA 4WX3A 2L38A 2OFCA 2KS4A 4TSPA 1Y2VA 3VWIA 3QDUA 3QDXA 4YLDA 1O72A 4TSLA 1Y2TA 4HPQB 1KD6A 3W9PA 4WDCA 5BPGA 4JOXA 4TSNA 1Y2UA 1GWYA 1O71A 3QDWA 3ZWGA 4Z2SA 3QDTA 5JHFB 1XI0A 4Z2FA 1TZQA 3A57A 4Z2QA 4OEBA 3QDYA 1X99A 2OFDA 4P1WB 2L2BA
chains in the Genus database with same CATH topology
3LIMA 2OFEA 4TSYA 1IAZA 1Y2WA 3QDSA 4TSOA 3QDVA 4TSQA 3ZWJA 1Y2XA 2L38A 2OFCA 2KS4A 4TSPA 1Y2VA 3VWIA 3QDUA 3QDXA 4YLDA 1O72A 4TSLA 1Y2TA 1KD6A 3W9PA 4WDCA 5BPGA 4TSNA 1Y2UA 1GWYA 1O71A 3QDWA 3ZWGA 4Z2SA 3QDTA 1XI0A 4Z2FA 1TZQA 4Z2QA 3QDYA 1X99A 2OFDA 2L2BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LIM A;  2OFE A;  4TSY A;  1IAZ A;  1Y2W A;  3QDS A;  4TSO A;  3QDV A;  4TSQ A;  3ZWJ A;  1Y2X A;  2L38 A;  2OFC A;  2KS4 A;  4TSP A;  1Y2V A;  3VWI A;  3QDU A;  3QDX A;  4YLD A;  1O72 A;  4TSL A;  1Y2T A;  1KD6 A;  3W9P A;  4WDC A;  5BPG A;  4TSN A;  1Y2U A;  1GWY A;  1O71 A;  3QDW A;  3ZWG A;  4Z2S A;  3QDT A;  1XI0 A;  4Z2F A;  1TZQ A;  4Z2Q A;  3QDY A;  1X99 A;  2OFD A;  2L2B A; 
#chains in the Genus database with same CATH topology
 3LIM A;  2OFE A;  4TSY A;  1IAZ A;  1Y2W A;  3QDS A;  4TSO A;  3QDV A;  4TSQ A;  4WX5 A;  3ZWJ A;  1Y2X A;  4WX3 A;  2L38 A;  2OFC A;  2KS4 A;  4TSP A;  1Y2V A;  3VWI A;  3QDU A;  3QDX A;  4YLD A;  1O72 A;  4TSL A;  1Y2T A;  4HPQ B;  1KD6 A;  3W9P A;  4WDC A;  5BPG A;  4JOX A;  4TSN A;  1Y2U A;  1GWY A;  1O71 A;  3QDW A;  3ZWG A;  4Z2S A;  3QDT A;  5JHF B;  1XI0 A;  4Z2F A;  1TZQ A;  3A57 A;  4Z2Q A;  4OEB A;  3QDY A;  1X99 A;  2OFD A;  4P1W B;  2L2B A; 
#chains in the Genus database with same CATH homology
 3LIM A;  2OFE A;  4TSY A;  1IAZ A;  1Y2W A;  3QDS A;  4TSO A;  3QDV A;  4TSQ A;  3ZWJ A;  1Y2X A;  2L38 A;  2OFC A;  2KS4 A;  4TSP A;  1Y2V A;  3VWI A;  3QDU A;  3QDX A;  4YLD A;  1O72 A;  4TSL A;  1Y2T A;  1KD6 A;  3W9P A;  4WDC A;  5BPG A;  4TSN A;  1Y2U A;  1GWY A;  1O71 A;  3QDW A;  3ZWG A;  4Z2S A;  3QDT A;  1XI0 A;  4Z2F A;  1TZQ A;  4Z2Q A;  3QDY A;  1X99 A;  2OFD A;  2L2B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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