4TSPA

Crystal structure of frac with dhpc bound (crystal form ii)
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
177
structure length
177
Chain Sequence
DVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
pubmed doi rcsb
molecule tags Toxin
source organism Actinia fragacea
molecule keywords Fragaceatoxin C
total genus 47
structure length 177
sequence length 177
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 4tspA00
1XI0A 3ZWGA 1Y2VA 5BPGA 4Z2FA 4TSQA 3QDTA 3QDYA 1O72A 1O71A 3QDVA 4TSPA 1Y2WA 3QDWA 2OFCA 4YLDA 4TSOA 4Z2SA 1Y2XA 3W9PA 4TSLA 2L2BA 3QDXA 3ZWJA 1KD6A 2KS4A 3VWIA 1Y2TA 4Z2QA 4WDCA 1TZQA 1IAZA 3QDUA 1Y2UA 1X99A 4TSYA 1GWYA 2OFEA 2OFDA 3QDSA 3LIMA 2L38A 4TSNA
chains in the Genus database with same CATH superfamily
1XI0A 3ZWGA 1Y2VA 5BPGA 4WX5A 5JHFB 4JOXA 4Z2FA 4TSQA 3QDTA 3QDYA 3A57A 1O72A 1O71A 3QDVA 4TSPA 1Y2WA 3QDWA 2OFCA 4YLDA 4TSOA 4Z2SA 1Y2XA 3W9PA 4TSLA 2L2BA 3QDXA 3ZWJA 1KD6A 2KS4A 3VWIA 1Y2TA 4Z2QA 4WDCA 4P1WB 1TZQA 4OEBA 1IAZA 3QDUA 1Y2UA 1X99A 4TSYA 4WX3A 1GWYA 2OFEA 2OFDA 3QDSA 3LIMA 4HPQB 2L38A 4TSNA
chains in the Genus database with same CATH topology
1XI0A 3ZWGA 1Y2VA 5BPGA 4Z2FA 4TSQA 3QDTA 3QDYA 1O72A 1O71A 3QDVA 4TSPA 1Y2WA 3QDWA 2OFCA 4YLDA 4TSOA 4Z2SA 1Y2XA 3W9PA 4TSLA 2L2BA 3QDXA 3ZWJA 1KD6A 2KS4A 3VWIA 1Y2TA 4Z2QA 4WDCA 1TZQA 1IAZA 3QDUA 1Y2UA 1X99A 4TSYA 1GWYA 2OFEA 2OFDA 3QDSA 3LIMA 2L38A 4TSNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XI0 A;  3ZWG A;  1Y2V A;  5BPG A;  4Z2F A;  4TSQ A;  3QDT A;  3QDY A;  1O72 A;  1O71 A;  3QDV A;  4TSP A;  1Y2W A;  3QDW A;  2OFC A;  4YLD A;  4TSO A;  4Z2S A;  1Y2X A;  3W9P A;  4TSL A;  2L2B A;  3QDX A;  3ZWJ A;  1KD6 A;  2KS4 A;  3VWI A;  1Y2T A;  4Z2Q A;  4WDC A;  1TZQ A;  1IAZ A;  3QDU A;  1Y2U A;  1X99 A;  4TSY A;  1GWY A;  2OFE A;  2OFD A;  3QDS A;  3LIM A;  2L38 A;  4TSN A; 
#chains in the Genus database with same CATH topology
 1XI0 A;  3ZWG A;  1Y2V A;  5BPG A;  4WX5 A;  5JHF B;  4JOX A;  4Z2F A;  4TSQ A;  3QDT A;  3QDY A;  3A57 A;  1O72 A;  1O71 A;  3QDV A;  4TSP A;  1Y2W A;  3QDW A;  2OFC A;  4YLD A;  4TSO A;  4Z2S A;  1Y2X A;  3W9P A;  4TSL A;  2L2B A;  3QDX A;  3ZWJ A;  1KD6 A;  2KS4 A;  3VWI A;  1Y2T A;  4Z2Q A;  4WDC A;  4P1W B;  1TZQ A;  4OEB A;  1IAZ A;  3QDU A;  1Y2U A;  1X99 A;  4TSY A;  4WX3 A;  1GWY A;  2OFE A;  2OFD A;  3QDS A;  3LIM A;  4HPQ B;  2L38 A;  4TSN A; 
#chains in the Genus database with same CATH homology
 1XI0 A;  3ZWG A;  1Y2V A;  5BPG A;  4Z2F A;  4TSQ A;  3QDT A;  3QDY A;  1O72 A;  1O71 A;  3QDV A;  4TSP A;  1Y2W A;  3QDW A;  2OFC A;  4YLD A;  4TSO A;  4Z2S A;  1Y2X A;  3W9P A;  4TSL A;  2L2B A;  3QDX A;  3ZWJ A;  1KD6 A;  2KS4 A;  3VWI A;  1Y2T A;  4Z2Q A;  4WDC A;  1TZQ A;  1IAZ A;  3QDU A;  1Y2U A;  1X99 A;  4TSY A;  1GWY A;  2OFE A;  2OFD A;  3QDS A;  3LIM A;  2L38 A;  4TSN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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