4TSQA

Crystal structure of frac with dhpc bound (crystal form iii)
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
177
structure length
177
Chain Sequence
DVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
pubmed doi rcsb
molecule tags Toxin
source organism Actinia fragacea
molecule keywords Fragaceatoxin C
total genus 46
structure length 177
sequence length 177
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2014-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 4tsqA00
2OFCA 1IAZA 2OFDA 2OFEA 1KD6A 1X99A 4TSPA 4TSQA 4TSOA 3LIMA 3W9PA 1O72A 1XI0A 1Y2TA 3QDVA 1O71A 3QDSA 4TSYA 4YLDA 4Z2SA 3QDTA 4WDCA 3ZWGA 2L38A 3QDYA 5BPGA 1TZQA 1Y2UA 4Z2FA 2KS4A 3ZWJA 1Y2WA 3VWIA 1Y2VA 3QDWA 4TSNA 4TSLA 1Y2XA 4Z2QA 3QDUA 2L2BA 3QDXA 1GWYA
chains in the Genus database with same CATH superfamily
5JHFB 2OFCA 1IAZA 2OFDA 2OFEA 4WX5A 4P1WB 1KD6A 1X99A 4TSPA 4TSQA 4TSOA 3LIMA 3W9PA 1O72A 1XI0A 1Y2TA 3QDVA 1O71A 3QDSA 4HPQB 4TSYA 4YLDA 4Z2SA 3QDTA 4WDCA 3ZWGA 2L38A 3QDYA 4WX3A 5BPGA 1TZQA 1Y2UA 3A57A 4Z2FA 2KS4A 4OEBA 3ZWJA 1Y2WA 3VWIA 1Y2VA 3QDWA 4TSNA 4TSLA 1Y2XA 4Z2QA 3QDUA 2L2BA 4JOXA 3QDXA 1GWYA
chains in the Genus database with same CATH topology
2OFCA 1IAZA 2OFDA 2OFEA 1KD6A 1X99A 4TSPA 4TSQA 4TSOA 3LIMA 3W9PA 1O72A 1XI0A 1Y2TA 3QDVA 1O71A 3QDSA 4TSYA 4YLDA 4Z2SA 3QDTA 4WDCA 3ZWGA 2L38A 3QDYA 5BPGA 1TZQA 1Y2UA 4Z2FA 2KS4A 3ZWJA 1Y2WA 3VWIA 1Y2VA 3QDWA 4TSNA 4TSLA 1Y2XA 4Z2QA 3QDUA 2L2BA 3QDXA 1GWYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OFC A;  1IAZ A;  2OFD A;  2OFE A;  1KD6 A;  1X99 A;  4TSP A;  4TSQ A;  4TSO A;  3LIM A;  3W9P A;  1O72 A;  1XI0 A;  1Y2T A;  3QDV A;  1O71 A;  3QDS A;  4TSY A;  4YLD A;  4Z2S A;  3QDT A;  4WDC A;  3ZWG A;  2L38 A;  3QDY A;  5BPG A;  1TZQ A;  1Y2U A;  4Z2F A;  2KS4 A;  3ZWJ A;  1Y2W A;  3VWI A;  1Y2V A;  3QDW A;  4TSN A;  4TSL A;  1Y2X A;  4Z2Q A;  3QDU A;  2L2B A;  3QDX A;  1GWY A; 
#chains in the Genus database with same CATH topology
 5JHF B;  2OFC A;  1IAZ A;  2OFD A;  2OFE A;  4WX5 A;  4P1W B;  1KD6 A;  1X99 A;  4TSP A;  4TSQ A;  4TSO A;  3LIM A;  3W9P A;  1O72 A;  1XI0 A;  1Y2T A;  3QDV A;  1O71 A;  3QDS A;  4HPQ B;  4TSY A;  4YLD A;  4Z2S A;  3QDT A;  4WDC A;  3ZWG A;  2L38 A;  3QDY A;  4WX3 A;  5BPG A;  1TZQ A;  1Y2U A;  3A57 A;  4Z2F A;  2KS4 A;  4OEB A;  3ZWJ A;  1Y2W A;  3VWI A;  1Y2V A;  3QDW A;  4TSN A;  4TSL A;  1Y2X A;  4Z2Q A;  3QDU A;  2L2B A;  4JOX A;  3QDX A;  1GWY A; 
#chains in the Genus database with same CATH homology
 2OFC A;  1IAZ A;  2OFD A;  2OFE A;  1KD6 A;  1X99 A;  4TSP A;  4TSQ A;  4TSO A;  3LIM A;  3W9P A;  1O72 A;  1XI0 A;  1Y2T A;  3QDV A;  1O71 A;  3QDS A;  4TSY A;  4YLD A;  4Z2S A;  3QDT A;  4WDC A;  3ZWG A;  2L38 A;  3QDY A;  5BPG A;  1TZQ A;  1Y2U A;  4Z2F A;  2KS4 A;  3ZWJ A;  1Y2W A;  3VWI A;  1Y2V A;  3QDW A;  4TSN A;  4TSL A;  1Y2X A;  4Z2Q A;  3QDU A;  2L2B A;  3QDX A;  1GWY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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