4TSYA

Crystal structure of frac with lipids
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
176
structure length
176
Chain Sequence
VAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
pubmed doi rcsb
molecule tags Toxin
source organism Actinia fragacea
molecule keywords Fragaceatoxin C
total genus 50
structure length 176
sequence length 176
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06369 Anemone_cytotox Sea anemone cytotoxic protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.270.20 Mainly Beta Sandwich Mutm (Fpg) Protein; Chain: A, domain 2 Cytolysin/lectin 4tsyA00
2KS4A 4TSOA 3ZWGA 2L2BA 4TSPA 4TSYA 1Y2VA 3W9PA 2OFEA 2OFDA 3QDVA 1TZQA 4YLDA 1X99A 1GWYA 1Y2UA 3QDXA 2OFCA 3QDSA 3QDTA 1Y2WA 2L38A 1Y2XA 1O72A 4TSQA 1O71A 3LIMA 3QDYA 4WDCA 4Z2SA 4Z2QA 1KD6A 4TSLA 1XI0A 4TSNA 3VWIA 3QDWA 1IAZA 5BPGA 4Z2FA 1Y2TA 3ZWJA 3QDUA
chains in the Genus database with same CATH superfamily
2KS4A 4TSOA 3ZWGA 2L2BA 4TSPA 4OEBA 4TSYA 1Y2VA 3W9PA 4WX3A 2OFEA 2OFDA 3QDVA 1TZQA 4YLDA 1X99A 1GWYA 1Y2UA 3A57A 3QDXA 2OFCA 3QDSA 3QDTA 1Y2WA 4JOXA 2L38A 1Y2XA 1O72A 4P1WB 4TSQA 1O71A 3LIMA 3QDYA 4WDCA 4Z2SA 4Z2QA 1KD6A 4TSLA 1XI0A 4TSNA 3VWIA 5JHFB 3QDWA 1IAZA 4HPQB 4WX5A 4Z2FA 5BPGA 1Y2TA 3ZWJA 3QDUA
chains in the Genus database with same CATH topology
2KS4A 4TSOA 3ZWGA 2L2BA 4TSPA 4TSYA 1Y2VA 3W9PA 2OFEA 2OFDA 3QDVA 1TZQA 4YLDA 1X99A 1GWYA 1Y2UA 3QDXA 2OFCA 3QDSA 3QDTA 1Y2WA 2L38A 1Y2XA 1O72A 4TSQA 1O71A 3LIMA 3QDYA 4WDCA 4Z2SA 4Z2QA 1KD6A 4TSLA 1XI0A 4TSNA 3VWIA 3QDWA 1IAZA 5BPGA 4Z2FA 1Y2TA 3ZWJA 3QDUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KS4 A;  4TSO A;  3ZWG A;  2L2B A;  4TSP A;  4TSY A;  1Y2V A;  3W9P A;  2OFE A;  2OFD A;  3QDV A;  1TZQ A;  4YLD A;  1X99 A;  1GWY A;  1Y2U A;  3QDX A;  2OFC A;  3QDS A;  3QDT A;  1Y2W A;  2L38 A;  1Y2X A;  1O72 A;  4TSQ A;  1O71 A;  3LIM A;  3QDY A;  4WDC A;  4Z2S A;  4Z2Q A;  1KD6 A;  4TSL A;  1XI0 A;  4TSN A;  3VWI A;  3QDW A;  1IAZ A;  5BPG A;  4Z2F A;  1Y2T A;  3ZWJ A;  3QDU A; 
#chains in the Genus database with same CATH topology
 2KS4 A;  4TSO A;  3ZWG A;  2L2B A;  4TSP A;  4OEB A;  4TSY A;  1Y2V A;  3W9P A;  4WX3 A;  2OFE A;  2OFD A;  3QDV A;  1TZQ A;  4YLD A;  1X99 A;  1GWY A;  1Y2U A;  3A57 A;  3QDX A;  2OFC A;  3QDS A;  3QDT A;  1Y2W A;  4JOX A;  2L38 A;  1Y2X A;  1O72 A;  4P1W B;  4TSQ A;  1O71 A;  3LIM A;  3QDY A;  4WDC A;  4Z2S A;  4Z2Q A;  1KD6 A;  4TSL A;  1XI0 A;  4TSN A;  3VWI A;  5JHF B;  3QDW A;  1IAZ A;  4HPQ B;  4WX5 A;  4Z2F A;  5BPG A;  1Y2T A;  3ZWJ A;  3QDU A; 
#chains in the Genus database with same CATH homology
 2KS4 A;  4TSO A;  3ZWG A;  2L2B A;  4TSP A;  4TSY A;  1Y2V A;  3W9P A;  2OFE A;  2OFD A;  3QDV A;  1TZQ A;  4YLD A;  1X99 A;  1GWY A;  1Y2U A;  3QDX A;  2OFC A;  3QDS A;  3QDT A;  1Y2W A;  2L38 A;  1Y2X A;  1O72 A;  4TSQ A;  1O71 A;  3LIM A;  3QDY A;  4WDC A;  4Z2S A;  4Z2Q A;  1KD6 A;  4TSL A;  1XI0 A;  4TSN A;  3VWI A;  3QDW A;  1IAZ A;  5BPG A;  4Z2F A;  1Y2T A;  3ZWJ A;  3QDU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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