The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
31
|
sequence length |
113
|
structure length |
113
|
Chain Sequence |
MFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors.
pubmed doi rcsb |
| molecule keywords |
Macrophage migration inhibitory factor
|
| molecule tags |
Isomerase/isomerase inhibitor
|
| source organism |
Homo sapiens
|
| total genus |
31
|
| structure length |
113
|
| sequence length |
113
|
| chains with identical sequence |
B, C, D, E, F
|
| ec nomenclature |
ec
5.3.2.1: Phenylpyruvate tautomerase. |
| pdb deposition date | 2015-03-27 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01187 | MIF | Macrophage migration inhibitory factor (MIF) |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Macrophage Migration Inhibitory Factor | Macrophage Migration Inhibitory Factor |
#chains in the Genus database with same CATH superfamily 2WKF B; 2X4K A; 2OOZ A; 4PKZ A; 5HVT A; 1CGQ A; 2ORM A; 3L5T A; 4P7M A; 3M20 A; 4Z15 A; 5BSJ A; 3U18 A; 3C6V A; 3L5P A; 3MB2 A; 3FWU A; 4LHO A; 5EIZ A; 5BS9 A; 4LHP A; 2XCZ A; 3RY0 A; 1BJP A; 4PLU A; 3HOF A; 4OTC A; 3MF7 A; 5BSC A; 4GRN A; 3ABF A; 3N4D A; 5J7P A; 1GYY A; 4ETG A; 3MLC A; 3WNS A; 3EJ9 B; 2AAJ A; 3MB2 B; 4WRB A; 1MFF A; 4OTB A; 3IJG A; 1MFI A; 4Q3F A; 4XX7 A; 3JSF A; 3T5S A; 5BSI A; 3EJ7 A; 4TRF A; 3KER A; 2AAG A; 2FLZ A; 3RF4 A; 1MWW A; 1GYJ A; 3L5R A; 1CA7 A; 1OTG A; 1S0Y A; 4PKK A; 4TRU A; 4JJ9 A; 4WR8 A; 2FM7 A; 1GIF A; 1U9D A; 3DJH A; 4GRP A; 3CE4 A; 4Z1U A; 4GRR A; 4GRO A; 3SMB A; 3DJI A; 2AAL A; 4NWQ B; 1GCZ A; 1OTF A; 4U5P A; 4OSF A; 5CLN A; 5B4O A; 4F2K A; 2OOW A; 4U5R A; 3N4G A; 3L5V A; 2WKB A; 4XX8 A; 4JCU A; 3B64 A; 4Z1T A; 1UIZ A; 3E6Q A; 4GUM A; 4GRQ A; 3JSG A; 3L5S A; 2WKF A; 3WNR A; 1FIM A; 4FDX A; 1GD0 A; 4P7S A; 3MF8 A; 3M21 A; 3N4H A; 5HVV A; 4M1A A; 3MJZ A; 2FLT A; 4EUI A; 4X1C A; 2OS5 A; 3EJ7 B; 3FWT A; 3L5U A; 4P01 A; 4GRU A; 3SMC A; 1S0Y B; 5HVS A; 3GAD A; 3EJ3 A; 4OTA A; 4NWP E; 3JTU A; 3EJ9 A; 4P0H A; 2OP8 A; 2OOH A; 4FAZ A; 4LKB A; 3GAC A; 2OPA A; 1HFO A; 5CLO A; 1DPT A; 5J7Q A; 1LJT A; 3WNT A; 1GYX A; 3KAN A; 4X19 A; 4K9G A; 4DH4 A; 3EJ3 B; 2GDG A; 4OYQ A; 3B9S A; 1MIF A; 3IJJ A; 4EVG A; 1P1G A; 3RF5 A; 4X1C C; #chains in the Genus database with same CATH topology 2WKF B; 2X4K A; 2OOZ A; 4PKZ A; 5HVT A; 1CGQ A; 2ORM A; 3L5T A; 4P7M A; 3M20 A; 4Z15 A; 5BSJ A; 3U18 A; 3C6V A; 3L5P A; 3MB2 A; 3FWU A; 4LHO A; 5EIZ A; 5BS9 A; 4LHP A; 2XCZ A; 3RY0 A; 1BJP A; 4PLU A; 3HOF A; 4OTC A; 3MF7 A; 5BSC A; 4GRN A; 3ABF A; 3N4D A; 5J7P A; 1GYY A; 4ETG A; 3MLC A; 3WNS A; 3EJ9 B; 2AAJ A; 3MB2 B; 4WRB A; 1MFF A; 4OTB A; 3IJG A; 1MFI A; 4Q3F A; 4XX7 A; 3JSF A; 3T5S A; 5BSI A; 3EJ7 A; 4TRF A; 3KER A; 2AAG A; 2FLZ A; 3RF4 A; 1MWW A; 1GYJ A; 3L5R A; 1CA7 A; 1OTG A; 1S0Y A; 4PKK A; 4TRU A; 4JJ9 A; 4WR8 A; 2FM7 A; 1GIF A; 1U9D A; 3DJH A; 4GRP A; 3CE4 A; 4Z1U A; 4GRR A; 4GRO A; 3SMB A; 3DJI A; 2AAL A; 4NWQ B; 1GCZ A; 1OTF A; 4U5P A; 4OSF A; 5CLN A; 5B4O A; 4F2K A; 2OOW A; 4U5R A; 3N4G A; 3L5V A; 2WKB A; 4XX8 A; 4JCU A; 3B64 A; 4Z1T A; 1UIZ A; 3E6Q A; 4GUM A; 4GRQ A; 3JSG A; 3L5S A; 2WKF A; 3WNR A; 1FIM A; 4FDX A; 1GD0 A; 4P7S A; 3MF8 A; 3M21 A; 3N4H A; 5HVV A; 4M1A A; 3MJZ A; 2FLT A; 4EUI A; 4X1C A; 2OS5 A; 3EJ7 B; 3FWT A; 3L5U A; 4P01 A; 4GRU A; 3SMC A; 1S0Y B; 5HVS A; 3GAD A; 3EJ3 A; 4OTA A; 4NWP E; 3JTU A; 3EJ9 A; 4P0H A; 2OP8 A; 2OOH A; 4FAZ A; 4LKB A; 3GAC A; 2OPA A; 1HFO A; 5CLO A; 1DPT A; 5J7Q A; 1LJT A; 3WNT A; 1GYX A; 3KAN A; 4X19 A; 4K9G A; 4DH4 A; 3EJ3 B; 2GDG A; 4OYQ A; 3B9S A; 1MIF A; 3IJJ A; 4EVG A; 1P1G A; 3RF5 A; 4X1C C; #chains in the Genus database with same CATH homology 2WKF B; 2X4K A; 2OOZ A; 4PKZ A; 5HVT A; 1CGQ A; 2ORM A; 3L5T A; 4P7M A; 3M20 A; 4Z15 A; 5BSJ A; 3U18 A; 3C6V A; 3L5P A; 3MB2 A; 3FWU A; 4LHO A; 5EIZ A; 5BS9 A; 4LHP A; 2XCZ A; 3RY0 A; 1BJP A; 4PLU A; 3HOF A; 4OTC A; 3MF7 A; 5BSC A; 4GRN A; 3ABF A; 3N4D A; 5J7P A; 1GYY A; 4ETG A; 3MLC A; 3WNS A; 3EJ9 B; 2AAJ A; 3MB2 B; 4WRB A; 1MFF A; 4OTB A; 3IJG A; 1MFI A; 4Q3F A; 4XX7 A; 3JSF A; 3T5S A; 5BSI A; 3EJ7 A; 4TRF A; 3KER A; 2AAG A; 2FLZ A; 3RF4 A; 1MWW A; 1GYJ A; 3L5R A; 1CA7 A; 1OTG A; 1S0Y A; 4PKK A; 4TRU A; 4JJ9 A; 4WR8 A; 2FM7 A; 1GIF A; 1U9D A; 3DJH A; 4GRP A; 3CE4 A; 4Z1U A; 4GRR A; 4GRO A; 3SMB A; 3DJI A; 2AAL A; 4NWQ B; 1GCZ A; 1OTF A; 4U5P A; 4OSF A; 5CLN A; 5B4O A; 4F2K A; 2OOW A; 4U5R A; 3N4G A; 3L5V A; 2WKB A; 4XX8 A; 4JCU A; 3B64 A; 4Z1T A; 1UIZ A; 3E6Q A; 4GUM A; 4GRQ A; 3JSG A; 3L5S A; 2WKF A; 3WNR A; 1FIM A; 4FDX A; 1GD0 A; 4P7S A; 3MF8 A; 3M21 A; 3N4H A; 5HVV A; 4M1A A; 3MJZ A; 2FLT A; 4EUI A; 4X1C A; 2OS5 A; 3EJ7 B; 3FWT A; 3L5U A; 4P01 A; 4GRU A; 3SMC A; 1S0Y B; 5HVS A; 3GAD A; 3EJ3 A; 4OTA A; 4NWP E; 3JTU A; 3EJ9 A; 4P0H A; 2OP8 A; 2OOH A; 4FAZ A; 4LKB A; 3GAC A; 2OPA A; 1HFO A; 5CLO A; 1DPT A; 5J7Q A; 1LJT A; 3WNT A; 1GYX A; 3KAN A; 4X19 A; 4K9G A; 4DH4 A; 3EJ3 B; 2GDG A; 4OYQ A; 3B9S A; 1MIF A; 3IJJ A; 4EVG A; 1P1G A; 3RF5 A; 4X1C C;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
