4NWQB

Computationally designed two-component self-assembling tetrahedral cage, t33-21, crystallized in space group f4132
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
121
structure length
121
Chain Sequence
PHLVIEATANLRLETSPGELLEQANKALFASGQFGEADIKSRFVTLEAYRQGTAAVERAYLHACLSILDGRDIATRTLLGASLCAVLAEAVAGGGEEGVQVSVEVREMERLSYAKRVVARQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Accurate design of co-assembling multi-component protein nanomaterials.
pubmed doi rcsb
molecule tags Protein binding
source organism Pyrococcus horikoshii
molecule keywords Putative uncharacterized protein PH0671
total genus 33
structure length 121
sequence length 121
ec nomenclature
pdb deposition date 2013-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02962 CHMI 5-carboxymethyl-2-hydroxymuconate isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.429.10 Alpha Beta 2-Layer Sandwich Macrophage Migration Inhibitory Factor Macrophage Migration Inhibitory Factor 4nwqB00
4P01A 4WRBA 1MFIA 3N4HA 4LHOA 3C6VA 3N4GA 1MIFA 4JCUA 4P0HA 2WKBA 3N4DA 4GRUA 3WNRA 1BJPA 2FM7A 3SMCA 3MJZA 4Z1UA 4ETGA 3MF7A 4GRRA 4GUMA 2OOHA 4GRQA 1MWWA 2XCZA 1P1GA 1U9DA 1CA7A 4U5RA 3E6QA 4OTBA 1FIMA 1LJTA 1GYXA 4K9GA 3FWTA 3GACA 4LKBA 3L5UA 3M20A 5CLOA 3DJHA 2GDGA 4FDXA 5J7PA 4GROA 3EJ7B 3B9SA 4PKZA 3WNSA 5HVTA 3WNTA 4P7SA 3GADA 5BS9A 5BSCA 4FAZA 5CLNA 2OS5A 4P7MA 3U18A 3IJJA 5HVVA 4XX8A 3RF5A 1CGQA 1GYJA 4GRNA 2FLZA 4EUIA 1GYYA 4DH4A 3HOFA 4OTAA 3IJGA 3EJ3B 2AALA 5B4OA 3EJ9B 1S0YB 4Z1TA 3L5SA 1GD0A 1HFOA 5EIZA 3EJ7A 3FWUA 3JSFA 4EVGA 3MB2B 3T5SA 2OOZA 2OPAA 3L5RA 4XX7A 5J7QA 3SMBA 4LHPA 2FLTA 4Z15A 4WR8A 1GCZA 3CE4A 4PLUA 3DJIA 4U5PA 4OYQA 2AAGA 3L5PA 3EJ3A 3EJ9A 4F2KA 1S0YA 2ORMA 1DPTA 2OOWA 4TRUA 3MB2A 1OTFA 5BSJA 4X1CA 3JTUA 3RY0A 4NWPE 3ABFA 5HVSA 3JSGA 4M1AA 4X19A 4X1CC 2AAJA 3RF4A 1GIFA 3B64A 4OTCA 1OTGA 3MF8A 3L5TA 2WKFA 4OSFA 3MLCA 4PKKA 1MFFA 1UIZA 5BSIA 2X4KA 4TRFA 4GRPA 3KERA 4NWQB 2OP8A 2WKFB 4JJ9A 3L5VA 4Q3FA 3M21A 3KANA
chains in the Genus database with same CATH superfamily
4P01A 4WRBA 1MFIA 3N4HA 4LHOA 3C6VA 3N4GA 1MIFA 4JCUA 4P0HA 2WKBA 3N4DA 4GRUA 3WNRA 1BJPA 2FM7A 3SMCA 3MJZA 4Z1UA 4ETGA 3MF7A 4GRRA 4GUMA 2OOHA 4GRQA 1MWWA 2XCZA 1P1GA 1U9DA 1CA7A 4U5RA 3E6QA 4OTBA 1FIMA 1LJTA 1GYXA 4K9GA 3FWTA 3GACA 4LKBA 3L5UA 3M20A 5CLOA 3DJHA 2GDGA 4FDXA 5J7PA 4GROA 3EJ7B 3B9SA 4PKZA 3WNSA 5HVTA 3WNTA 4P7SA 3GADA 5BS9A 5BSCA 4FAZA 5CLNA 2OS5A 4P7MA 3U18A 3IJJA 5HVVA 4XX8A 3RF5A 1CGQA 1GYJA 4GRNA 2FLZA 4EUIA 1GYYA 4DH4A 3HOFA 4OTAA 3IJGA 3EJ3B 2AALA 5B4OA 3EJ9B 1S0YB 4Z1TA 3L5SA 1GD0A 1HFOA 5EIZA 3EJ7A 3FWUA 3JSFA 4EVGA 3MB2B 3T5SA 2OOZA 2OPAA 3L5RA 4XX7A 5J7QA 3SMBA 4LHPA 2FLTA 4Z15A 4WR8A 1GCZA 3CE4A 4PLUA 3DJIA 4U5PA 4OYQA 2AAGA 3L5PA 3EJ3A 3EJ9A 4F2KA 1S0YA 2ORMA 1DPTA 2OOWA 4TRUA 3MB2A 1OTFA 5BSJA 4X1CA 3JTUA 3RY0A 4NWPE 3ABFA 5HVSA 3JSGA 4M1AA 4X19A 4X1CC 2AAJA 3RF4A 1GIFA 3B64A 4OTCA 1OTGA 3MF8A 3L5TA 2WKFA 4OSFA 3MLCA 4PKKA 1MFFA 1UIZA 5BSIA 2X4KA 4TRFA 4GRPA 3KERA 4NWQB 2OP8A 2WKFB 4JJ9A 3L5VA 4Q3FA 3M21A 3KANA
chains in the Genus database with same CATH topology
4P01A 4WRBA 1MFIA 3N4HA 4LHOA 3C6VA 3N4GA 1MIFA 4JCUA 4P0HA 2WKBA 3N4DA 4GRUA 3WNRA 1BJPA 2FM7A 3SMCA 3MJZA 4Z1UA 4ETGA 3MF7A 4GRRA 4GUMA 2OOHA 4GRQA 1MWWA 2XCZA 1P1GA 1U9DA 1CA7A 4U5RA 3E6QA 4OTBA 1FIMA 1LJTA 1GYXA 4K9GA 3FWTA 3GACA 4LKBA 3L5UA 3M20A 5CLOA 3DJHA 2GDGA 4FDXA 5J7PA 4GROA 3EJ7B 3B9SA 4PKZA 3WNSA 5HVTA 3WNTA 4P7SA 3GADA 5BS9A 5BSCA 4FAZA 5CLNA 2OS5A 4P7MA 3U18A 3IJJA 5HVVA 4XX8A 3RF5A 1CGQA 1GYJA 4GRNA 2FLZA 4EUIA 1GYYA 4DH4A 3HOFA 4OTAA 3IJGA 3EJ3B 2AALA 5B4OA 3EJ9B 1S0YB 4Z1TA 3L5SA 1GD0A 1HFOA 5EIZA 3EJ7A 3FWUA 3JSFA 4EVGA 3MB2B 3T5SA 2OOZA 2OPAA 3L5RA 4XX7A 5J7QA 3SMBA 4LHPA 2FLTA 4Z15A 4WR8A 1GCZA 3CE4A 4PLUA 3DJIA 4U5PA 4OYQA 2AAGA 3L5PA 3EJ3A 3EJ9A 4F2KA 1S0YA 2ORMA 1DPTA 2OOWA 4TRUA 3MB2A 1OTFA 5BSJA 4X1CA 3JTUA 3RY0A 4NWPE 3ABFA 5HVSA 3JSGA 4M1AA 4X19A 4X1CC 2AAJA 3RF4A 1GIFA 3B64A 4OTCA 1OTGA 3MF8A 3L5TA 2WKFA 4OSFA 3MLCA 4PKKA 1MFFA 1UIZA 5BSIA 2X4KA 4TRFA 4GRPA 3KERA 4NWQB 2OP8A 2WKFB 4JJ9A 3L5VA 4Q3FA 3M21A 3KANA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P01 A;  4WRB A;  1MFI A;  3N4H A;  4LHO A;  3C6V A;  3N4G A;  1MIF A;  4JCU A;  4P0H A;  2WKB A;  3N4D A;  4GRU A;  3WNR A;  1BJP A;  2FM7 A;  3SMC A;  3MJZ A;  4Z1U A;  4ETG A;  3MF7 A;  4GRR A;  4GUM A;  2OOH A;  4GRQ A;  1MWW A;  2XCZ A;  1P1G A;  1U9D A;  1CA7 A;  4U5R A;  3E6Q A;  4OTB A;  1FIM A;  1LJT A;  1GYX A;  4K9G A;  3FWT A;  3GAC A;  4LKB A;  3L5U A;  3M20 A;  5CLO A;  3DJH A;  2GDG A;  4FDX A;  5J7P A;  4GRO A;  3EJ7 B;  3B9S A;  4PKZ A;  3WNS A;  5HVT A;  3WNT A;  4P7S A;  3GAD A;  5BS9 A;  5BSC A;  4FAZ A;  5CLN A;  2OS5 A;  4P7M A;  3U18 A;  3IJJ A;  5HVV A;  4XX8 A;  3RF5 A;  1CGQ A;  1GYJ A;  4GRN A;  2FLZ A;  4EUI A;  1GYY A;  4DH4 A;  3HOF A;  4OTA A;  3IJG A;  3EJ3 B;  2AAL A;  5B4O A;  3EJ9 B;  1S0Y B;  4Z1T A;  3L5S A;  1GD0 A;  1HFO A;  5EIZ A;  3EJ7 A;  3FWU A;  3JSF A;  4EVG A;  3MB2 B;  3T5S A;  2OOZ A;  2OPA A;  3L5R A;  4XX7 A;  5J7Q A;  3SMB A;  4LHP A;  2FLT A;  4Z15 A;  4WR8 A;  1GCZ A;  3CE4 A;  4PLU A;  3DJI A;  4U5P A;  4OYQ A;  2AAG A;  3L5P A;  3EJ3 A;  3EJ9 A;  4F2K A;  1S0Y A;  2ORM A;  1DPT A;  2OOW A;  4TRU A;  3MB2 A;  1OTF A;  5BSJ A;  4X1C A;  3JTU A;  3RY0 A;  4NWP E;  3ABF A;  5HVS A;  3JSG A;  4M1A A;  4X19 A;  4X1C C;  2AAJ A;  3RF4 A;  1GIF A;  3B64 A;  4OTC A;  1OTG A;  3MF8 A;  3L5T A;  2WKF A;  4OSF A;  3MLC A;  4PKK A;  1MFF A;  1UIZ A;  5BSI A;  2X4K A;  4TRF A;  4GRP A;  3KER A;  4NWQ B;  2OP8 A;  2WKF B;  4JJ9 A;  3L5V A;  4Q3F A;  3M21 A;  3KAN A; 
#chains in the Genus database with same CATH topology
 4P01 A;  4WRB A;  1MFI A;  3N4H A;  4LHO A;  3C6V A;  3N4G A;  1MIF A;  4JCU A;  4P0H A;  2WKB A;  3N4D A;  4GRU A;  3WNR A;  1BJP A;  2FM7 A;  3SMC A;  3MJZ A;  4Z1U A;  4ETG A;  3MF7 A;  4GRR A;  4GUM A;  2OOH A;  4GRQ A;  1MWW A;  2XCZ A;  1P1G A;  1U9D A;  1CA7 A;  4U5R A;  3E6Q A;  4OTB A;  1FIM A;  1LJT A;  1GYX A;  4K9G A;  3FWT A;  3GAC A;  4LKB A;  3L5U A;  3M20 A;  5CLO A;  3DJH A;  2GDG A;  4FDX A;  5J7P A;  4GRO A;  3EJ7 B;  3B9S A;  4PKZ A;  3WNS A;  5HVT A;  3WNT A;  4P7S A;  3GAD A;  5BS9 A;  5BSC A;  4FAZ A;  5CLN A;  2OS5 A;  4P7M A;  3U18 A;  3IJJ A;  5HVV A;  4XX8 A;  3RF5 A;  1CGQ A;  1GYJ A;  4GRN A;  2FLZ A;  4EUI A;  1GYY A;  4DH4 A;  3HOF A;  4OTA A;  3IJG A;  3EJ3 B;  2AAL A;  5B4O A;  3EJ9 B;  1S0Y B;  4Z1T A;  3L5S A;  1GD0 A;  1HFO A;  5EIZ A;  3EJ7 A;  3FWU A;  3JSF A;  4EVG A;  3MB2 B;  3T5S A;  2OOZ A;  2OPA A;  3L5R A;  4XX7 A;  5J7Q A;  3SMB A;  4LHP A;  2FLT A;  4Z15 A;  4WR8 A;  1GCZ A;  3CE4 A;  4PLU A;  3DJI A;  4U5P A;  4OYQ A;  2AAG A;  3L5P A;  3EJ3 A;  3EJ9 A;  4F2K A;  1S0Y A;  2ORM A;  1DPT A;  2OOW A;  4TRU A;  3MB2 A;  1OTF A;  5BSJ A;  4X1C A;  3JTU A;  3RY0 A;  4NWP E;  3ABF A;  5HVS A;  3JSG A;  4M1A A;  4X19 A;  4X1C C;  2AAJ A;  3RF4 A;  1GIF A;  3B64 A;  4OTC A;  1OTG A;  3MF8 A;  3L5T A;  2WKF A;  4OSF A;  3MLC A;  4PKK A;  1MFF A;  1UIZ A;  5BSI A;  2X4K A;  4TRF A;  4GRP A;  3KER A;  4NWQ B;  2OP8 A;  2WKF B;  4JJ9 A;  3L5V A;  4Q3F A;  3M21 A;  3KAN A; 
#chains in the Genus database with same CATH homology
 4P01 A;  4WRB A;  1MFI A;  3N4H A;  4LHO A;  3C6V A;  3N4G A;  1MIF A;  4JCU A;  4P0H A;  2WKB A;  3N4D A;  4GRU A;  3WNR A;  1BJP A;  2FM7 A;  3SMC A;  3MJZ A;  4Z1U A;  4ETG A;  3MF7 A;  4GRR A;  4GUM A;  2OOH A;  4GRQ A;  1MWW A;  2XCZ A;  1P1G A;  1U9D A;  1CA7 A;  4U5R A;  3E6Q A;  4OTB A;  1FIM A;  1LJT A;  1GYX A;  4K9G A;  3FWT A;  3GAC A;  4LKB A;  3L5U A;  3M20 A;  5CLO A;  3DJH A;  2GDG A;  4FDX A;  5J7P A;  4GRO A;  3EJ7 B;  3B9S A;  4PKZ A;  3WNS A;  5HVT A;  3WNT A;  4P7S A;  3GAD A;  5BS9 A;  5BSC A;  4FAZ A;  5CLN A;  2OS5 A;  4P7M A;  3U18 A;  3IJJ A;  5HVV A;  4XX8 A;  3RF5 A;  1CGQ A;  1GYJ A;  4GRN A;  2FLZ A;  4EUI A;  1GYY A;  4DH4 A;  3HOF A;  4OTA A;  3IJG A;  3EJ3 B;  2AAL A;  5B4O A;  3EJ9 B;  1S0Y B;  4Z1T A;  3L5S A;  1GD0 A;  1HFO A;  5EIZ A;  3EJ7 A;  3FWU A;  3JSF A;  4EVG A;  3MB2 B;  3T5S A;  2OOZ A;  2OPA A;  3L5R A;  4XX7 A;  5J7Q A;  3SMB A;  4LHP A;  2FLT A;  4Z15 A;  4WR8 A;  1GCZ A;  3CE4 A;  4PLU A;  3DJI A;  4U5P A;  4OYQ A;  2AAG A;  3L5P A;  3EJ3 A;  3EJ9 A;  4F2K A;  1S0Y A;  2ORM A;  1DPT A;  2OOW A;  4TRU A;  3MB2 A;  1OTF A;  5BSJ A;  4X1C A;  3JTU A;  3RY0 A;  4NWP E;  3ABF A;  5HVS A;  3JSG A;  4M1A A;  4X19 A;  4X1C C;  2AAJ A;  3RF4 A;  1GIF A;  3B64 A;  4OTC A;  1OTG A;  3MF8 A;  3L5T A;  2WKF A;  4OSF A;  3MLC A;  4PKK A;  1MFF A;  1UIZ A;  5BSI A;  2X4K A;  4TRF A;  4GRP A;  3KER A;  4NWQ B;  2OP8 A;  2WKF B;  4JJ9 A;  3L5V A;  4Q3F A;  3M21 A;  3KAN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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