5BO9A

Structure of human sialyltransferase st8siaiii in complex with cmp-3fneu5ac and sia-6s-lacnac
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
291
structure length
286
Chain Sequence
WKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFESHQLPAEFQLLYRMHGEGLTKLTLSHCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransfer
total genus 96
structure length 286
sequence length 291
chains with identical sequence B
ec nomenclature ec 2.4.99.-:
pdb deposition date 2015-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00777 Glyco_transf_29 Glycosyltransferase family 29 (sialyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1480.20 Alpha Beta Alpha-Beta Complex sialyltransferase cstii, chain A sialyltransferase cstii, chain A 5bo9A00
5BO9A 5CXYA 2WNFA 5BO7A 4MPSA 5BO6A 5BO8A 4JS1A 4JS2A 2WMLA 2WNBA
chains in the Genus database with same CATH superfamily
2X61A 2P56A 5CXYA 1RO8A 2X63A 1RO7A 5BO9A 5BO7A 2DRJA 2WQQA 5BO8A 4JS1A 4JS2A 2WMLA 2WNBA 2X62A 2WNFA 2P2VA 4MPSA 5BO6A
chains in the Genus database with same CATH topology
5BO9A 5CXYA 2WNFA 5BO7A 4MPSA 5BO6A 5BO8A 4JS1A 4JS2A 2WMLA 2WNBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BO9 A;  5CXY A;  2WNF A;  5BO7 A;  4MPS A;  5BO6 A;  5BO8 A;  4JS1 A;  4JS2 A;  2WML A;  2WNB A; 
#chains in the Genus database with same CATH topology
 2X61 A;  2P56 A;  5CXY A;  1RO8 A;  2X63 A;  1RO7 A;  5BO9 A;  5BO7 A;  2DRJ A;  2WQQ A;  5BO8 A;  4JS1 A;  4JS2 A;  2WML A;  2WNB A;  2X62 A;  2WNF A;  2P2V A;  4MPS A;  5BO6 A; 
#chains in the Genus database with same CATH homology
 5BO9 A;  5CXY A;  2WNF A;  5BO7 A;  4MPS A;  5BO6 A;  5BO8 A;  4JS1 A;  4JS2 A;  2WML A;  2WNB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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